Výsledky vyhledávání - "Wasfy M, Obeidat"

Effect of post-compaction heating on characteristics of microcrystalline cellulose compacts

Autor: Shadi F. Gharaibeh, Wasfy M. Obeidat, Nizar Al-Zoubi

Publikováno v: e-Polymers. 22:536-543

Compacts of microcrystalline cellulose were prepared at applied compression pressures of 21, 32, 43, 53, and 64 MPa. Compacts were subjected to elevated temperatures of 125°C, 150°C, and 175°C according to a 5-min heating program. The effect of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9bfe601c821112be619584ecd22c6148
https://doi.org/10.1515/epoly-2022-0049

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Assessment of Once Daily Controlled-release Ibuprofen Matrix Tablets Prepared using Eudragit ®E100/Carbopol® 971P NF Polymers and their Salt Combinations

Autor: Wasfy M. Obeidat, Mohammad Mohammad Al Natour

Publikováno v: Current Drug Delivery. 19:74-85

Introduction: Hydrophilic polymers that swell or dissolve in aqueous media can have the potential to prepare controlled/sustained dosage forms for weakly acidic and poorly soluble drugs. Objective: The main objective of this study is to utilize Eudra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03c7af0e7a712cfb26c64f13535f07de
https://doi.org/10.2174/1567201818999210625100126

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The Influence of Drugs Solubilities and Chitosan-TPP Formulation Parameters on the Mean Hydrodynamic Diameters and Drugs Entrapment Efficiencies into Chitosan-TPP Nanoparticles

Autor: Wasfy M. Obeidat, Shadi F. Gharaibeh, Abdolelah Jaradat

Publikováno v: AAPS PharmSciTech. 23

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f10d00da58e6db9cf9f4b2bf057be303
https://doi.org/10.1208/s12249-022-02420-8

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The Influence of Drugs Solubilities and Chitosan-TPP Formulation Parameters on the Mean Hydrodynamic Diameters and Drugs Entrapment Efficiencies into Chitosan-TPP Nanoparticles

Autor: Wasfy M, Obeidat, Shadi F, Gharaibeh, Abdolelah, Jaradat

Publikováno v: AAPS PharmSciTech. 23(7)

Chitosan is a natural, biocompatible polymer. The aim of this work was to study the influence of drug solubility in 2% v/v acetic acid, formulation parameters, on mean hydrodynamic (MHD) diameters and drug entrapment efficiencies (% EE) into chitosan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::de4ea8921ea3b7105b5a43c61dea190b
https://pubmed.ncbi.nlm.nih.gov/36138243

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Preparation and Evaluation of Ternary Polymeric Blends for Controlled Release Matrices Containing Weakly Basic Model Drug

Autor: Shadi F. Gharaibeh, Wasfy M. Obeidat, Abdolelah A Jaradat, Osama Abualsuod

Publikováno v: Current Drug Delivery. 18:54-64

Objective: The objective of this study was to evaluate the suitability of a ternary mixture of smart polymers comprised of Eudragit®E100, Eudragit®L100, and sodium alginate to serve as a carrier for sustained drug release for weakly basic drugs. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1a49d7601846b129e394b70ca63998
https://doi.org/10.2174/1567201817666200731170040

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Assessment of Once Daily Controlled-release Ibuprofen Matrix Tablets Prepared using Eudragit

Autor: Wasfy M, Obeidat, Mohammad Ahmad, Al-Natour

Publikováno v: Current drug delivery. 19(1)

Hydrophilic polymers that swell or dissolve in aqueous media can have the potential to prepare controlled/sustained dosage forms for weakly acidic and poorly soluble drugs.The main objective of this study is to utilize EudragitCombinations of the pol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3f3a983622a840bc874e568648fa5c5f
https://pubmed.ncbi.nlm.nih.gov/34176461

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Evaluation of Predictors of Protein Relative Stability Obtained by Solid-State Hydrogen/Deuterium Exchange Monitored by FTIR

Autor: Robin H. Bogner, Michael J. Pikal, Rui Fang, Wasfy M. Obeidat

Publikováno v: Pharmaceutical Research. 37

Hydrogen/deuterium (H/D) exchange over a range of temperatures suggests a protein structural/mobility transition in the solid state below the system glass transition temperature (Tg). The purpose of this study was to determine whether solid-state pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73f3ee02ab86835e18ef1a00c1cebd67
https://doi.org/10.1007/s11095-020-02897-7

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Evaluation of Spironolactone Solid Dispersions Prepared by Co-Spray Drying With Soluplus® and Polyvinylpyrrolidone and Influence of Tableting on Drug Release

Autor: Nizar Al-Zoubi, Faten Odah, Wasfy M. Obeidat, Ioannis Nikolakakis, Ioannis Partheniadis, Ahmad Aljaberi

Publikováno v: Journal of Pharmaceutical Sciences. 107:2385-2398

Solid dispersions of spironolactone with Soluplus® and polyvinylpyrrolidone were prepared by spray drying according to a mixture experimental design and evaluated for moisture content, particle size, drug solubility, crystallinity (powder X-ray diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47511090cc04356a4ee2c62c75791837
https://doi.org/10.1016/j.xphs.2018.04.028

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Development of a Mini-Freeze Dryer for Material-Sparing Laboratory Processing with Representative Product Temperature History

Autor: William J. Kessler, Wasfy M. Obeidat, Michael J. Pikal, Ekneet Kaur Sahni

Publikováno v: AAPS PharmSciTech. 19:599-609

The goal of the work described in this publication was to evaluate a new, small, material-sparing freeze dryer, denoted as the “mini-freeze dryer or mini-FD”, capable of reproducing the product temperature history of larger freeze dryers, thereby

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f75a922c698aa8af206a0cb078ca69b
https://doi.org/10.1208/s12249-017-0871-5

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