Genome-Wide miRNA Expression Profiling of Molecular Subgroups of Peripheral T-cell Lymphoma

Autor: Mallick Saumyaranjan, Graham W. Slack, Federica Melle, Giovanna Motta, Dennis D. Weisenburger, Soon Thye Lim, Kerry J. Savage, Catalina Amador, Andrew L. Feldman, Lisa M. Rimsza, Wing C. Chan, Timothy C. Greiner, Tayla B. Heavican, Waseem Gul Lone, German Ott, Stefano Pileri, Andreas Rosenwald, Sunandini Sharma, Alyssa Bouska, Tyler A. Herek, Javeed Iqbal, Jiayu Yu, Timothy W. McKeithan, Julie M. Vose, Choon Kiat Ong, James R. Cook

Publikováno v: Clin Cancer Res

Purpose: Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of non–Hodgkin lymphomas with aggressive clinical behavior. We performed comprehensive miRNA profiling in PTCLs and corresponding normal CD4+ Th1/2 and TFH-like polarized subsets t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbf8a7041624375ed8d5c9f060e10b6
https://doi.org/10.1158/1078-0432.ccr-21-0573

A Novel Antibody Drug Conjugate (ADC) Targeting Cell Surface Heat Shock Protein 70 (csHSP70) Is Active Against Pre-Clinical Models of Peripheral T-Cell Lymphoma (PTCL)

Autor: Javeed Iqbal, Isere Kuiatse, Alyssa Bouska, Richard J. Jones, Hua Wang, Rajan Kumar Choudhary, Waseem Gul Lone, Robert Z. Orlowski, Francisco Vega

Publikováno v: Blood. 138:870-870

Background: Neoplasms of T-cell or natural killer/T-cell origin account for 10-15% of all non-Hodgkin lymphomas (NHLs) in the United States, and 30% or more of NHLs in African and Asian countries, and tumors from post-thymic or peripheral T-cells are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d8a33b97f1659f2eb62c231593356fd
https://doi.org/10.1182/blood-2021-150842

Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma

Autor: Tayla Heavican, Javeed Iqbal, Andreas Rosenwald, Kai Fu, Julie M. Vose, Laurence de Leval, Sylvia Hartmann, Bhavana J. Dave, Choon Kiat Ong, Yuping Li, Koichi Ohshima, Corinne Haioun, Masao Seto, Ryan A. Wilcox, Edoardo Missiaglia, Timothy W. McKeithan, Waseem Gul Lone, Giorgio Inghirami, Maria Antonella Laginestra, Alyssa Bouska, Philippe Gaulard, Randy D. Gascoyne, Elaine S. Jaffe, Jadd M. Stevens, Jiayu Yu, Bin Tean Teh, Francesco d'Amore, Francesco Bertoni, German Ott, François Lemonnier, Wing C. Chan, Soon Thye Lim, Weiwei Zhang, Cynthia M. Lachel, Elias Campo, Qiang Gong, Rita M. Braziel, Noriaki Yoshida, Timothy Greiner, Maarja-Liisa Nairismagi, Martin Bjerregård Pedersen, Louis M. Staudt, Stefano Pileri, Lisa M. Rimsza, Dennis D. Weisenburger, Chao Wang, Catalina Amador

Publikováno v: Heavican, T B, Bouska, A, Yu, J, Lone, W G, Amador, C, Gong, Q, Zhang, W, Li, Y, Dave, B J, Nairismägi, M-L, Greiner, T C, Vose, J, Weisenburger, D D, Lachel, C, Wang, C, Fu, K, Stevens, J, Lim, S T, Ong, C K, Gascoyne, R D, Missiaglia, E, Lemonnier, F, Haioun, C, Hartmann, S, Pedersen, M B, Laginestra, MA, Wilcox, R, The, BT, Yoshida, N, Ohshima, K, Seto, M, Rosenwald, A, Ott, G, Campo, E, Rimsza, L M, Jaffe, E S, Braziel, R M, d'Amore, F A, Inghirami, G, Bertoni, F, de Leval, L, Gaulard, P, Staudt, L M, McKeithan, T W, Pileri, S A, Chan, W C & Iqbal, J 2019, ' Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma ', Blood, vol. 133, no. 15, pp. 1664-1676 . https://doi.org/10.1182/blood-2018-09-872549

Peripheral T-cell lymphoma (PTCL) is a group of complex clinicopathological entities, often associated with an aggressive clinical course. Angioimmunoblastic T-cell lymphoma (AITL) and PTCL-not otherwise specified (PTCL-NOS) are the 2 most frequent c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1816540e6e9dd40de5b60405b672d6
https://pure.au.dk/portal/da/publications/genetic-drivers-of-oncogenic-pathways-in-molecular-subgroups-of-peripheral-tcell-lymphoma(c36deca9-bc03-44ba-87a4-eeb61498c32d).html

Reproducing the molecular subclassification of peripheral T-cell lymphoma–NOS by immunohistochemistry

Autor: Waseem Gul Lone, Lynette M. Smith, Karen Tatiana Galvis, Anja Mottok, Catalina Amador, Julie M. Vose, Claudio Agostinelli, Alyssa Bouska, German Ott, Soon Thye Lim, Timothy C. Greiner, Elaine S. Jaffe, Lisa M. Rimsza, Francesco d'Amore, Martin Bjerregård Pedersen, Wing C. Chan, Louis M. Staudt, Stefano Pileri, Andrew L. Feldman, Andreas Rosenwald, Kerry J. Savage, Choon Kiat Ong, Sarah L. Ondrejka, Dennis D. Weisenburger, Laurence de Leval, Philippe Gaulard, Tayla Heavican, Joo Y. Song, Javeed Iqbal, Elias Campo

Publikováno v: Amador, C, Greiner, T C, Heavican, T B, Smith, L M, Galvis, K T, Lone, W G, Bouska, A, D'amore, F, Bjerregård Pedersen, M, Pileri, S A, Agostinelli, C, Feldman, A L, Rosenwald, A, Ott, G, Mottok, A, Savage, K J, de Leval, L, Gaulard, P, Lim, S T, Ong, C K, Ondrejka, S L, Song, J, Campo, E, Jaffe, E S, Staudt, L M, Rimsza, L M, Vose, J, Weisenburger, D D, Chan, W C, Iqbal, J & Lymphoma/Leukemia Molecular Profiling Project 2019, ' Reproducing the Molecular Subclassification of Peripheral T-cell Lymphoma-NOS by Immunohistochemistry ', Blood, vol. 134, no. 24, pp. 2159-2170 . https://doi.org/10.1182/blood.2019000779

Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of mature T-cell malignancies with approximately one-third of cases designated as PTCL-not otherwise specified (PTCL-NOS). Using gene expression profiling (GEP), we have previously defined tw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586dd2c64ffbec38f513cdf85a971808
http://hdl.handle.net/11585/725163

Molecular Insights Into Pathogenesis of Peripheral T Cell Lymphoma: a Review

Autor: Jayadev Manikkam Umakanthan, Aisha Alkhiniji, Javeed Iqbal, Waseem Gul Lone

Publikováno v: Current hematologic malignancy reports. 13(4)

Peripheral T cell lymphoma (PTCL) is a heterogeneous group of lymphoproliferative neoplasms, with at least 29 distinct entities described in current WHO classification. Using present diagnostic approaches, more than a third of PTCL cases cannot be cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1044cebeeed9d74398e981ec569b5dd
https://pubmed.ncbi.nlm.nih.gov/29951889