Induced Pluripotent Stem Cells and Their Use in Cardiac and Neural Regenerative Medicine

Autor: Stepanka Skalova, Tereza Svadlakova, Wasay Mohiuddin Shaikh Qureshi, Kapil Dev, Jaroslav Mokry

Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 2, Pp 4043-4067 (2015)

Stem cells are unique pools of cells that are crucial for embryonic development and maintenance of adult tissue homeostasis. The landmark Nobel Prize winning research by Yamanaka and colleagues to induce pluripotency in somatic cells has reshaped the

Externí odkaz: https://doaj.org/article/cb17c89df41e4bcb996ac5bbab169353

Signaling Involved in Hair Follicle Morphogenesis and Development

Autor: Pisal Rishikaysh, Kapil Dev, Daniel Diaz, Wasay Mohiuddin Shaikh Qureshi, Stanislav Filip, Jaroslav Mokry

Publikováno v: International Journal of Molecular Sciences, Vol 15, Iss 1, Pp 1647-1670 (2014)

Hair follicle morphogenesis depends on Wnt, Shh, Notch, BMP and other signaling pathways interplay between epithelial and mesenchymal cells. The Wnt pathway plays an essential role during hair follicle induction, Shh is involved in morphogenesis and

Externí odkaz: https://doaj.org/article/d2d02748c9384be9b837a1be5741ca81

Disease modeling of core pre-mRNA splicing factor haploinsufficiency

Autor: Kathryn E. Hentges, Huw B. Thomas, Weronika A. Buczek, Tracy A Briggs, Wasay Mohiuddin Shaikh Qureshi, Charlie Rowlands, Raymond T. O'Keefe, Katherine A. Wood, William G. Newman, Simon J. Hubbard

Publikováno v: Human Molecular Genetics
Wood, K, Rowland, C F, Shaikh Qureshi, W M, Thomas, H, Buczek, W, Briggs, T, Hubbard, S, Hentges, K, Newman, W & O'Keefe, R 2019, ' Disease modelling of core pre-mRNA splicing factor haploinsufficiency ', Hum Mol Genet, vol. 28, no. 22, pp. 3704-3723 . https://doi.org/10.1093/hmg/ddz169

The craniofacial disorder mandibulofacial dysostosis Guion-Almeida type is caused by haploinsufficiency of the U5 snRNP gene EFTUD2/SNU114. However, it is unclear how reduced expression of this core pre-mRNA splicing factor leads to craniofacial defe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ada3ab6a68910034f47b973e67b596
https://pubmed.ncbi.nlm.nih.gov/31304552

Chick Embryonic Cardiomyocyte Micromass System for Assessing Developmental Cardiotoxicity of Drugs

Autor: Wasay Mohiuddin Shaikh, Qureshi, Margaret K, Pratten

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1797

Heart is the first mesodermal organ to develop and is sensitive to life-threatening toxic effects of drugs during development. A number of methods have been devised to study developmental cardiotoxic effects of drugs including micromass system. The m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::379c70f277a920553a3a06460d32c38e
https://pubmed.ncbi.nlm.nih.gov/29896690

Induced Pluripotent Stem Cells and Their Use in Cardiac and Neural Regenerative Medicine

Autor: Tereza Svadlakova, Stepanka Skalova, Wasay Mohiuddin Shaikh Qureshi, Kapil Dev, Jaroslav Mokry

Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 2, Pp 4043-4067 (2015)
International Journal of Molecular Sciences

Stem cells are unique pools of cells that are crucial for embryonic development and maintenance of adult tissue homeostasis. The landmark Nobel Prize winning research by Yamanaka and colleagues to induce pluripotency in somatic cells has reshaped the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f985bdb3a09e5da78faf818876e02dc
https://doi.org/10.3390/ijms16024043