Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Wasana, Stitchantrakul"'
PARP1pred: a web server for screening the bioactivity of inhibitors against DNA repair enzyme PARP-1
Autor:
Tassanee Lerksuthirat, Sermsiri Chitphuk, Wasana Stitchantrakul, Donniphat Dejsuphong, Aijaz Ahmad Malik, Chanin Nantasenamat
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 84-107 (2023)
Cancer is the leading cause of death worldwide, resulting in the mortality of more than 10 million people in 2020, according to Global Cancer Statistics 2020. A potential cancer therapy involves targeting the DNA repair process by inhibiting PARP-1.
Externí odkaz:
https://doaj.org/article/5a7513611529407db49b6202f3926303
Autor:
Tassanee Lerksuthirat, Pasinee On‐yam, Sermsiri Chitphuk, Wasana Stitchantrakul, David S. Newburg, Ardythe L. Morrow, Suradej Hongeng, Wararat Chiangjong, Somchai Chutipongtanate
Publikováno v:
Global Challenges, Vol 7, Iss 3, Pp n/a-n/a (2023)
Abstract Anticancer peptides (ACPs) are rising as a new strategy for cancer therapy. However, traditional laboratory screening to find and identify novel ACPs from hundreds to thousands of peptides is costly and time consuming. Here, a sequential pro
Externí odkaz:
https://doaj.org/article/18ae5a0382bb4d9a89f3fd160df78fda
Autor:
Rakkreat Wikiniyadhanee, Tassanee Lerksuthirat, Wasana Stitchantrakul, Sermsiri Chitphuk, Thanyachai Sura, Donniphat Dejsuphong
Publikováno v:
FEBS Open Bio, Vol 10, Iss 10, Pp 2055-2071 (2020)
Tripartite motif‐containing protein 29 (TRIM29) is involved in DNA double‐strand break (DSB) repair. However, the specific roles of TRIM29 in DNA repair are not clearly understood. To investigate the involvement of TRIM29 in DNA DSB repair, we di
Externí odkaz:
https://doaj.org/article/780932cbbbd44c02bf790b37d879fc90
Autor:
Rakkreat Wikiniyadhanee, Tassanee Lerksuthirat, Wasana Stitchantrakul, Sermsiri Chitphuk, Shunichi Takeda, Donniphat Dejsuphong
Publikováno v:
BioMed Research International. 2023:1-12
The inhibition of poly(ADP-ribose) polymerases (PARPs) and ataxia telangiectasia and Rad3-related (ATR) would be an alternative approach for cancer treatments. The aim of this study is to investigate the synergy of the different combinations of PARP
Autor:
Tassanee Lerksuthirat, Rakkreat Wikiniyadhanee, Sermsiri Chitphuk, Wasana Stitchantrakul, Somponnat Sampattavanich, Siwanon Jirawatnotai, Juangjun Jumpathong, Donniphat Dejsuphong
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1680 (2020)
Recent developments in chemotherapy focus on target-specific mechanisms, which occur only in cancer cells and minimize the effects on normal cells. DNA damage and repair pathways are a promising target in the treatment of cancer. In order to identify
Externí odkaz:
https://doaj.org/article/3930ab349b5c4d70b5950e5856eaf543
Autor:
Wasana Stitchantrakul, Siwanon Jirawatnotai, Sermsiri Chitphuk, Donniphat Dejsuphong, Nauljun Stansook, Nut Pipatpanyanugoon, Tassanee Lerksuthirat, Rakkreat Wikiniyadhanee
Publikováno v:
Genes to Cells. 25:718-729
Ring finger protein 43 (RNF43) is an E3 ubiquitin ligase which is well-known for its role in negative regulation of the Wnt-signaling pathway. However, the function in DNA double-strand break repairs has not been investigated. In this study, we used
Autor:
Sermsiri Chitphuk, Tassanee Lerksuthirat, Wasana Stitchantrakul, Donniphat Dejsuphong, Thanyachai Sura, Rakkreat Wikiniyadhanee
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 10, Iss 10, Pp 2055-2071 (2020)
FEBS Open Bio, Vol 10, Iss 10, Pp 2055-2071 (2020)
TRIM29 is involved in DNA double‐strand break repair but the specific roles of TRIM29 in DNA repair are not clearly understood. We proposed that TRIM29 regulates the choice of DNA DSB repair pathway by facilitating 53BP1 accumulation to promote NHE
Autor:
Donniphat Dejsuphong, Piyamitr Sritara, Atchara Tunteeratum, Pollawat Khemthong, Aruchalean Taweewongsounton, Thanyachai Sura, Sermsiri Chitphuk, Wasana Stitchantrakul
Publikováno v:
Neurological Sciences. 40:1729-1732
Spinal muscular atrophy (SMA) is one of the leading causes of death in infants and young children from heritable diseases. Patients diagnosed with SMA develop symmetrical progressive muscle weakness and atrophy from degeneration of alpha motor neuron
Autor:
Sermsiri Chitphuk, Wasana Stitchantrakul, Siwanon Jirawatnotai, Rakkreat Wikiniyadhanee, Somponnat Sampattavanich, Donniphat Dejsuphong, Tassanee Lerksuthirat, Juangjun Jumpathong
Publikováno v:
Biomolecules, Vol 10, Iss 1680, p 1680 (2020)
Biomolecules
Volume 10
Issue 12
Biomolecules
Volume 10
Issue 12
Recent developments in chemotherapy focus on target-specific mechanisms, which occur only in cancer cells and minimize the effects on normal cells. DNA damage and repair pathways are a promising target in the treatment of cancer. In order to identify