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Akademický článek

Cish knockout mice exhibit similar outcomes to malaria infection despite altered hematopoietic responses

Autor: Asha L. Lakkavaram, Saeed Maymand, Wasan Naser, Alister C. Ward, Tania F. de Koning-Ward

Publikováno v: Frontiers in Microbiology, Vol 14 (2023)

The Cytokine-inducible Src homology 2 domain-containing (CISH) protein is a negative feedback regulator induced by cytokines that play key roles in immunity and erythropoiesis. Single nucleotide polymorphisms (SNPs) in the human CISH gene have been a

Externí odkaz: https://doaj.org/article/9c4cdcc06a4342469784369a3cfd4690

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Akademický článek

Role of Cytokine-Inducible SH2 Domain-Containing (CISH) Protein in the Regulation of Erythropoiesis

Autor: Saeed Maymand, Asha L. Lakkavaram, Wasan Naser, Parisa Rasighaemi, Daniel Dlugolenski, Clifford Liongue, John Stambas, Tania F. de Koning-Ward, Alister C. Ward

Publikováno v: Biomolecules, Vol 13, Iss 10, p 1510 (2023)

The cytokine-inducible SH2 domain-containing (CISH) protein was the first member of the suppressor of cytokine signaling (SOCS) family of negative feedback regulators discovered, being identified in vitro as an inducible inhibitor of erythropoietin (

Externí odkaz: https://doaj.org/article/e419f84742744f50bc89c18b8ec24685

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Akademický článek

The Role of Cytokine-Inducible SH2 Domain-Containing Protein (CISH) in the Regulation of Basal and Cytokine-Mediated Myelopoiesis

Autor: Wasan Naser, Saeed Maymand, Daniel Dlugolenski, Faiza Basheer, Alister C. Ward

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 16, p 12757 (2023)

Cytokine-inducible SH2 domain-containing protein (CISH) is a member of the suppressor of cytokine signaling (SOCS) family of negative feedback regulators shown to play crucial roles in lymphoid cell development and function as well as appetite regula

Externí odkaz: https://doaj.org/article/b79378e7f8fa4b22a06f92fd68c26150

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Cytokine‐inducible SH2 domain containing protein contributes to regulation of adiposity, food intake, and glucose metabolism

Autor: Wasan, Naser, Saeed, Maymand, Leni R, Rivera, Timothy, Connor, Clifford, Liongue, Craig M, Smith, Kathryn, Aston-Mourney, Daniel R, McCulloch, Sean L, McGee, Alister C, Ward

Publikováno v: The FASEB Journal. 36

The cytokine-inducible SH2 domain containing protein (CISH) is the founding member of the suppressor of cytokine signaling (SOCS) family of negative feedback regulators and has been shown to be a physiological regulator of signaling in immune cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6027b7509dee28c895de60f27e74b223
https://doi.org/10.1096/fj.202101882r

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