Effect of Alkyl Chain Length and Linker Atom on the Crystal Packing in 6,12-Dialkoxy- And 6,12-Dialkylsulfanyl-Benzo[1,2- b:4,5- b′]bis[ b]benzothiophenes

Autor: Riaz, S, Edgar, M, Elsegood, MRJ, Horsburgh, L, Teat, SJ, Warwick, TG, Weaver, GW

Publikováno v: Crystal Growth and Design, vol 19, iss 9

The effect of varying the chain length on the solid state conformation and packing of 6,12-dialkoxy- and 6,12-dialkylsulfanyl-benzo[1,2-b:4,5-b′]bis[b]benzothiophenes has been studied. The compounds were prepared by SNAr reaction of 6,12-difluorben

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::ed6e6583e0f44c1ed1cf02a7289af329
https://escholarship.org/uc/item/1hw5d8cw

Crystal structure of Leishmania mexicana cysteine protease B in complex with a high-affinity azadipeptide nitrile inhibitor.

Autor: Ribeiro JFR; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil., Cianni L; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil., Li C; School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK., Warwick TG; School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK., de Vita D; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil., Rosini F; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil., Dos Reis Rocho F; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil., Martins FCP; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil., Kenny PW; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil., Lameira J; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil; Laboratory of Design and Development of Pharmaceuticals, Federal University of Pará, Belém, Brazil., Leitão A; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil., Emsley J; School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK. Electronic address: jonas.emsley@nottingham.ac.uk., Montanari CA; Medicinal and Biological Chemistry Group, Institute of Chemistry of São Carlos, University of São Paulo, São Carlos, Brazil. Electronic address: Carlos.Montanari@usp.br.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Nov 15; Vol. 28 (22), pp. 115743. Date of Electronic Publication: 2020 Sep 06.