Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Warunee Hanpithakpong"'
Autor:
Thanaporn Wattanakul, Mary Ellen Gilder, Rose McGready, Warunee Hanpithakpong, Nicholas P. J. Day, Nicholas J. White, François Nosten, Joel Tarning, Richard M. Hoglund
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Current guidelines advise against primaquine treatment for breastfeeding mothers to avoid the potential for haemolysis in infants with G6PD deficiency. To predict the haemolytic risk, the amount of drug received from the breast milk and the
Externí odkaz:
https://doaj.org/article/12525384aebe42e68770b27a8264b9c5
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Background Ivermectin is a widely used drug for the treatment of helminthiasis and filariasis worldwide, and it has also shown promise for malaria elimination through its potent mosquito-lethal activity. The objective of this study was to develop and
Externí odkaz:
https://doaj.org/article/e76ab4e7772146b99e96a835e0b2aa6b
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-16 (2022)
Abstract Background The enantiomers of the 8-aminoquinoline anti-malarial primaquine have different pharmacological properties. Development of an analytical method for simultaneous quantification of the enantiomers of primaquine and its metabolite, c
Externí odkaz:
https://doaj.org/article/90660e30bca746c09c1f0b98a377f573
Autor:
Palang Chotsiri, Issaka Zongo, Paul Milligan, Yves Daniel Compaore, Anyirékun Fabrice Somé, Daniel Chandramohan, Warunee Hanpithakpong, François Nosten, Brian Greenwood, Philip J. Rosenthal, Nicholas J. White, Jean-Bosco Ouédraogo, Joel Tarning
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Seasonal malaria chemoprevention provides substantial benefit for young children, but resistance to used drugs will likely develop. Here, Chotsiri et al. evaluate the use of dihydroartemisinin-piperaquine as a regimen in 179 children, and population-
Externí odkaz:
https://doaj.org/article/86ec31b424e24336afbb7777111820e8
Autor:
Sangdao Somsri, Mathirut Mungthin, Natthaporn Klubthawee, Poom Adisakwattana, Warunee Hanpithakpong, Ratchaneewan Aunpad
Publikováno v:
Antibiotics, Vol 10, Iss 12, p 1560 (2021)
Mitochondria are considered a novel drug target as they play a key role in energy production and programmed cell death of eukaryotic cells. The mitochondria of malaria parasites differ from those of their vertebrate hosts, contributing to the drug se
Externí odkaz:
https://doaj.org/article/e44f0dcaff6941ed8a47066236f9a0b0
Autor:
Steffen Borrmann, Philip Sasi, Leah Mwai, Mahfudh Bashraheil, Ahmed Abdallah, Steven Muriithi, Henrike Frühauf, Barbara Schaub, Johannes Pfeil, Judy Peshu, Warunee Hanpithakpong, Anja Rippert, Elizabeth Juma, Benjamin Tsofa, Moses Mosobo, Brett Lowe, Faith Osier, Greg Fegan, Niklas Lindegårdh, Alexis Nzila, Norbert Peshu, Margaret Mackinnon, Kevin Marsh
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26005 (2011)
The emergence of artemisinin-resistant P. falciparum malaria in South-East Asia highlights the need for continued global surveillance of the efficacy of artemisinin-based combination therapies.On the Kenyan coast we studied the treatment responses in
Externí odkaz:
https://doaj.org/article/666aa4208cf44281a14dc6263740e11b
Autor:
Kanokpich Puaprasert, Htun Htun Win, François Nosten, Suradet Thinraow, Widi Yotyingaphiram, Pornpimon Wilaisrisak, Joel Tarning, Aye Aye Aung, Mallika Imwong, James A Watson, Cindy S. Chu, Daniel Blessborn, Stephane Proux, Nicholas J. White, Aung Pyae Phyo, Nay Lin Soe, Clare L. Ling, Warunee Hanpithakpong
Publikováno v:
Antimicrobial agents and chemotherapy
BackgroundPrimaquine is the only widely available drug for radical cure of Plasmodium vivax malaria. There is uncertainty whether the pharmacokinetic properties of primaquine are altered significantly in childhood or not.MethodsGlucose-6-phosphate de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a95271e1332d912ee6df90a7415d19
https://doi.org/10.1128/aac.01302-21
https://doi.org/10.1128/aac.01302-21
Autor:
Warunee Hanpithakpong, Ratchaneewan Aunpad, Sangdao Somsri, Natthaporn Klubthawee, Poom Adisakwattana
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Antimicrobial peptides (AMPs) are promising alternatives to classical antibiotics for the treatment of drug-resistant infections. Due to their versatility and unlimited sequence space, AMPs can be rationally designed by modulating physicochemical det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42257d13b74135a2fa21cbc658afe70c
http://europepmc.org/articles/PMC7272617
http://europepmc.org/articles/PMC7272617
Autor:
Joel Tarning, Kalayanee Chairat, Borimas Hanboonkunupakarn, Daniel Blessborn, Warunee Hanpithakpong, Podjanee Jittamala, Sasithon Pukrittayakamee, Nicholas J. White, Nicholas P. J. Day
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives Characterization of the pharmacokinetic properties of the enantiomers of primaquine and carboxyprimaquine following administration of racemic primaquine given alone and in combination with commonly used antimalarial drugs. Methods Enantiom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d6018b23147f4ee5a5ca6bd55c29d9
http://europepmc.org/articles/PMC6198747
http://europepmc.org/articles/PMC6198747
Autor:
François Nosten, Nicholas J. White, Pharath Lim, Joel Tarning, Mats O. Karlsson, Aung Pyae Phyo, Warunee Hanpithakpong, Jesmin Lohy Das, Pascal Ringwald, Arjen M. Dondorp, Martin Bergstrand
Orally administered artemisinin-based combination therapy is the first-line treatment against uncomplicated P. falciparum malaria worldwide. However, the increasing prevalence of artemisinin resistance is threatening efforts to treat and eliminate ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498af73db5cb54f31c24cf6036d82c92
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-328533
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-328533
