Zobrazeno 1 - 10
of 443
pro vyhledávání: '"Warsow"'
Autor:
Stefan Gröschel, Daniel Hübschmann, Francesco Raimondi, Peter Horak, Gregor Warsow, Martina Fröhlich, Barbara Klink, Laura Gieldon, Barbara Hutter, Kortine Kleinheinz, David Bonekamp, Oliver Marschal, Priya Chudasama, Jagoda Mika, Marie Groth, Sebastian Uhrig, Stephen Krämer, Christoph Heining, Christoph E. Heilig, Daniela Richter, Eva Reisinger, Katrin Pfütze, Roland Eils, Stephan Wolf, Christof von Kalle, Christian Brandts, Claudia Scholl, Wilko Weichert, Stephan Richter, Sebastian Bauer, Roland Penzel, Evelin Schröck, Albrecht Stenzinger, Richard F. Schlenk, Benedikt Brors, Robert B. Russell, Hanno Glimm, Matthias Schlesner, Stefan Fröhling
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Chordomas are rare bone tumors with limited therapeutic options. Here, the authors identify molecular alterations associated with defective homologous recombination DNA repair in advanced chordomas and report prolonged response in a patient treated w
Externí odkaz:
https://doaj.org/article/ba10289481024dc5944d84dae65732a8
Autor:
Venu Thatikonda, S. M. Ashiqul Islam, Robert J. Autry, Barbara C. Jones, Susanne N. Gröbner, Gregor Warsow, Barbara Hutter, Daniel Huebschmann, Stefan Fröhling, Marcel Kool, Mirjam Blattner-Johnson, David T. W. Jones, Ludmil B. Alexandrov, Stefan M. Pfister, Natalie Jäger
Publikováno v:
Nature Cancer. 4:276-289
Analysis of mutational signatures can reveal underlying molecular mechanisms of the processes that have imprinted the somatic mutations found in cancer genomes. Here, we analyze single base substitutions and small insertions and deletions in pediatri
Autor:
Gregor Warsow, Daniel Hübschmann, Kortine Kleinheinz, Cathleen Nientiedt, Martina Heller, Laura Van Coile, Yanis Tolstov, Lukas Trennheuser, Kathrin Wieczorek, Carine Pecqueux, Claudia Gasch, Timur Kuru, Joanne Nyarangi-Dix, Gencay Hatiboglu, Dogu Teber, Sven Perner, Albrecht Stenzinger, Wilfried Roth, Boris Hadaschik, Sascha Pahernik, Dirk Jäger, Carsten Grüllich, Anette Duensing, Roland Eils, Matthias Schlesner, Holger Sültmann, Markus Hohenfellner, Stefan Duensing
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract A venous tumor thrombus (VTT) is a potentially lethal complication of renal cell carcinoma (RCC) but virtually nothing is known about the underlying natural history. Based on our observation that venous thrombi contain significant numbers of
Externí odkaz:
https://doaj.org/article/fdc0109087c648f893b957962fedc3ad
Autor:
Natallia Shved, Gregor Warsow, Felix Eichinger, David Hoogewijs, Simone Brandt, Peter Wild, Matthias Kretzler, Clemens D. Cohen, Maja T. Lindenmeyer
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Accumulating evidence suggests that dysregulation of hypoxia-regulated transcriptional mechanisms is involved in development of chronic kidney diseases (CKD). However, it remains unclear how hypoxia-induced transcription factors (HIFs) and s
Externí odkaz:
https://doaj.org/article/d0b078d380c64c128af4e76a7ea6e241
Autor:
Khreis, Haneen, Warsow, Karyn M., Verlinghieri, Ersilia, Guzman, Alvaro, Pellecuer, Luc, Ferreira, Antonio, Jones, Ian, Heinen, Eva, Rojas-Rueda, David, Mueller, Natalie, Schepers, Paul, Lucas, Karen, Nieuwenhuijsen, Mark
Publikováno v:
In Journal of Transport & Health September 2016 3(3):249-267
Akademický článek
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Autor:
Rouven Hoefflin, Bernd Lahrmann, Gregor Warsow, Daniel Hübschmann, Cathleen Spath, Britta Walter, Xin Chen, Luisa Hofer, Stephan Macher-Goeppinger, Yanis Tolstov, Nina Korzeniewski, Anette Duensing, Carsten Grüllich, Dirk Jäger, Sven Perner, Gita Schönberg, Joanne Nyarangi-Dix, Sanjay Isaac, Gencay Hatiboglu, Dogu Teber, Boris Hadaschik, Sascha Pahernik, Wilfried Roth, Roland Eils, Matthias Schlesner, Holger Sültmann, Markus Hohenfellner, Niels Grabe, Stefan Duensing
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
It has been increasingly recognised that tumours are not made up of a homogeneous population of cells. Here, the authors show heterogeneous expression of five protein markers in renal cell cancer and demonstrate that the progression of the tumour doe
Externí odkaz:
https://doaj.org/article/6b8b3ea588cd4746baa64e76cce15f72
Autor:
Markus Schillhabel, Alfonso Valencia, Anke K. Bergmann, Eva Reisinger, Hendrik G. Stunnenberg, Marc A. Weniger, Stephan H. Bernhart, Christoph Borst, Volker Hovestadt, Andrea Haake, Naveed Ishaque, Markus Loeffler, Christina Jäger-Schmidt, Matthias Bieg, Arndt Borkhardt, Gero Doose, Hans Binder, Jules Kerssemakers, Bernhard Radlwimmer, Markus Kreuz, Kortine Kleinheinz, Stephan Stilgenbauer, Andreas Rosenwald, Alexander Claviez, Benedikt Brors, Michael Hummel, Matthias Schlesner, Bingding Huang, Reiner Siebert, Peter Lichter, Chris Lawerenz, José I. Martín-Subero, Cristina López, Marc Zapatka, Monika Szczepanowski, Ole Ammerpohl, Umut H. Toprak, Peter Möller, Nagarajan Paramasivam, Wolfram Klapper, Philip Rosenstiel, Martin-Leo Hansmann, Dieter Kube, Helene Kretzmer, Ralf Küppers, Julia Richter, Steve Hoffmann, Sietse M. Aukema, Siegfried Haas, Jan O. Korbel, Dennis Karsch, Renée Beekman, Enrique Carrillo de Santa Pau, Roland Eils, Daniel Rico, Philipp Bruns, Jessica I. Hoell, Stephanie Sungalee, Dido Lenze, Sebastian M. Waszak, Gregor Warsow, Rabea Wagener, Joost H.A. Martens, German Ott, Lorenz Trümper, Peter F. Stadler, Daniel Hübschmann
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Leukemia
Leukemia : the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K.
Universitat Politècnica de Catalunya (UPC)
Leukemia
Leukemia : the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K.
B cells have the unique property to somatically alter their immunoglobulin (IG) genes by V(D)J recombination, somatic hypermutation (SHM) and class-switch recombination (CSR). Aberrant targeting of these mechanisms is implicated in lymphomagenesis, b
Autor:
S. Froehling, Mirjam Blattner-Johnson, Ludmil B. Alexandrov, Susanne N. Groebner, Venu Thatikonda, G. Warsow, D. Huebschmann, Stefan M. Pfister, B. C. Jones, Barbara Hutter, Natalie Jaeger, S. M. A. Islam, Dtw Jones
Analysis of mutational signatures can reveal the underlying molecular mechanisms of the processes that have imprinted the somatic mutations found in a cancer genome. Here, we present a pan-cancer mutational signatures analysis of single base substitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8af7d26ce001ab00658503c95687238d
https://doi.org/10.1101/2021.09.28.462210
https://doi.org/10.1101/2021.09.28.462210
Autor:
Martina Fröhlich, Gregor Warsow, Olaf Neumann, Benedikt Brors, Florian Weinberg, Stefan Fröhling, Viola Hollek, Dieter Henrik Heiland, Peter Horak, Hanno Glimm, Sandra Braun, Ricarda Griffin, Christoph Heining, Corinna Spohr, Wilko Weichert, Albrecht Stenzinger, Christof von Kalle, Tilman Brummer, Mary Iconomou, Barbara Hutter, Sebastian Uhrig, Michael Röring, David E. Reuss, Simon Kreutzfeldt
Publikováno v:
Oncogene. 39:814-832
Fusion proteins involving the BRAF serine/threonine kinase occur in many cancers. The oncogenic potential of BRAF fusions has been attributed to the loss of critical N-terminal domains that mediate BRAF autoinhibition. We used whole-exome and RNA seq