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Discovery of a first-in-class potent small molecule antagonist against the adrenomedullin-2 receptor
Autor:
Avgoustou, P., Jailani, A.B.A., Zirimwabagabo, J.-O., Tozer, M.J., Gibson, K.R., Glossop, P.A., Mills, J.E.J., Porter, R.A., Blaney, P., Bungay, P., WANG, N., Shaw, A., Bigos, K.J.A., Holmes, J.L., Warrington, J.I., Skerry, T.M., Harrity, J.P.A., Richards, G.O.
The hormone adrenomedullin has both physiological and pathological roles in biology. As a potent vasodilator, adrenomedullin is critically important in regulation of blood pressure, but it also has several roles in disease, of which its actions in ca
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https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::777c71de2e7e29c7278e83320d64db56
Akademický článek
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PURPOSE OF REVIEW: This study is to highlight recent discoveries associated with the role of calcitonin peptide family and their receptors in prostate cancer progression and bone metastasis. \ud \ud RECENT FINDINGS: Studies have linked adrenomedullin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::545261ea173034ca4aa958fdccb31417