Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Warren P Tate"'
Autor:
Beatriz Calvo-Flores Guzmán, SooHyun Kim, Bhavya Chawdhary, Katie Peppercorn, Warren P Tate, Henry J Waldvogel, Richard LM Faull, Johanna Montgomery, Andrea Kwakowsky
Publikováno v:
Molecules, Vol 25, Iss 3, p 693 (2020)
Alzheimer’s disease (AD) is a complex and chronic neurodegenerative disorder that involves a progressive and severe decline in cognition and memory. During the last few decades a considerable amount of research has been done in order to better unde
Externí odkaz:
https://doaj.org/article/4f197a38a05a4eebac1c6675168888dc
Autor:
Harold S Bernhardt, Warren P Tate
Publikováno v:
Frontiers in Ecology and Evolution, Vol 3 (2015)
It was Francis Crick who first asked why the ribosome contains so much RNA, and discussed the implications of this for the direct flow of genetic information from DNA to protein. Remarkable advances in our understanding of the ribosome and protein sy
Externí odkaz:
https://doaj.org/article/85a19eab45cd4317a9e81744b08b1ea1
Autor:
Suneeth F Mathew, Caillan Crowe-McAuliffe, Ryan Graves, Tony S Cardno, Cushla McKinney, Elizabeth S Poole, Warren P Tate
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122176 (2015)
HIV-1 utilises -1 programmed ribosomal frameshifting to translate structural and enzymatic domains in a defined proportion required for replication. A slippery sequence, U UUU UUA, and a stem-loop are well-defined RNA features modulating -1 frameshif
Externí odkaz:
https://doaj.org/article/87d15fa289194209897c68af85fac57f
Autor:
Tony S Cardno, Yosuke Shimaki, Brad E Sleebs, Kurt Lackovic, John P Parisot, Rebecca M Moss, Caillan Crowe-McAuliffe, Suneeth F Mathew, Christina D Edgar, Torsten Kleffmann, Warren P Tate
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139036 (2015)
Frameshifting during translation of viral or in rare cases cellular mRNA results in the synthesis of proteins from two overlapping reading frames within the same mRNA. In HIV-1 the protease, reverse transcriptase, and integrase enzymes are in a secon
Externí odkaz:
https://doaj.org/article/20a5de53f7ec45b591411810ac7d69b1
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Of those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ~ 10% develop the chronic post-viral debilitating condition, long COVID (LC). Although LC is a heterogeneous condition, about half of cases have typical pos
Externí odkaz:
https://doaj.org/article/f5128a19f70241a9ae8670312aa46d5e
Autor:
Margaret M Ryan, Brigid Ryan, Madeleine Kyrke-Smith, Barbara Logan, Warren P Tate, Wickliffe C Abraham, Joanna M Williams
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40538 (2012)
Long-term potentiation (LTP) is widely accepted as a cellular mechanism underlying memory processes. It is well established that LTP persistence is strongly dependent on activation of constitutive and inducible transcription factors, but there is lim
Externí odkaz:
https://doaj.org/article/7258b114130146e29906e4fa117826a1
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7165 (2023)
Secreted amyloid precursor protein alpha (sAPPα), processed from a parent mammalian brain protein, amyloid precursor protein, can modulate learning and memory. Recently it has been shown to modulate the transcriptome and proteome of human neurons, i
Externí odkaz:
https://doaj.org/article/6b8e7c03e5844f998cb18236369d33ae
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5124 (2023)
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex condition arising in susceptible people, predominantly following viral infection, but also other stressful events. The susceptibility factors discussed here are both genetic and
Externí odkaz:
https://doaj.org/article/e67fa1db1c4e4a4b99184df925b06c59
Autor:
Amber M. Helliwell, Peter A. Stockwell, Christina D. Edgar, Aniruddha Chatterjee, Warren P. Tate
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11852 (2022)
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex disease with variable severity. Patients experience frequent relapses where symptoms increase in severity, leaving them with a marked reduction in quality of life. Previous work
Externí odkaz:
https://doaj.org/article/fbc73694f3c34b15b6d924afab3e9112
Autor:
Rhys W. Livingstone, Megan K. Elder, Anurag Singh, Courteney M. Westlake, Warren P. Tate, Wickliffe C. Abraham, Joanna M. Williams
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Regulation of AMPA receptor expression by neuronal activity and neuromodulators is critical to the expression of both long-term potentiation (LTP) and memory. In particular, Ca2+-permeable AMPARs (CP-AMPAR) play a unique role in these processes due t
Externí odkaz:
https://doaj.org/article/9290877e3a9240328cd488775be4af9a