Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Warren N. D'Souza"'
Autor:
Warren N D'Souza, Jason Douangpanya, Sharon Mu, Peter Jaeckel, Ming Zhang, Joseph R Maxwell, James B Rottman, Katja Labitzke, Angela Willee, Holger Beckmann, Yingcai Wang, Yang Li, Ralf Schwandner, James A Johnston, Jennifer E Towne, Hailing Hsu
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180190 (2017)
Inflammatory bowel disease (IBD) is associated with a loss of intestinal barrier function and dysregulated immune responses. It has been shown that short chain fatty acids (SCFAs) are protective in IBD and that GPR43 mediates the protective effects o
Externí odkaz:
https://doaj.org/article/b23ee36446df4bf7bfe46cce97494f0c
Autor:
George Golovko, Wei Wu, Yi Xiao, Yuriy Fofanov, Warren N. D'Souza, Xiangsheng Huang, Tonyia Eaves-Pyles, Ye Zhao, Anthony J. Bilotta, Suxia Yao, Zhanju Liu, Qihong Zhao, Feidi Chen, Yingzi Cong, Mingming Sun
Publikováno v:
Mucosal immunology
The antimicrobial peptides (AMP) produced by intestinal epithelial cells (IEC) play crucial roles in the regulation of intestinal homeostasis by controlling microbiota. Gut microbiota has been shown to promote IEC expression of RegIIIγ and certain d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5d9934b50dc8a9e26d44ce584171e9
http://europepmc.org/articles/PMC5976519
http://europepmc.org/articles/PMC5976519
Autor:
Sharon Wannberg, Jay Rothstein, Daniel Chui, Luís Rato, Pedro Oliveira, Warren N. D'Souza, Tânia R. Dias, Raquel L. Bernardino, Marco G. Alves
Publikováno v:
Cell and tissue research. 378(2)
Lactate is a key metabolite for the normal occurrence of spermatogenesis. In the testis, lactate is produced by the Sertoli cells and transported to germline cells. Monocarboxylate transporters (MCTs) are key players in that process. Among the family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43ba11738c8bea3dc64c789384f7e97
https://pubmed.ncbi.nlm.nih.gov/31073907
https://pubmed.ncbi.nlm.nih.gov/31073907
Autor:
Peng Li, Joanne T. Hulme, Helen J. McBride, Kim Merriam, Jiansong Xie, Alice Bakker, Hong Sun, Anielka Montalvan, Richard Smith, John E. Sims, Roy A. Black, Kevin Moore, Christopher A. Gabel, Natalia Grinberg, James B. Rottman, Angela Willee, Ryan Case, Amy N. Duguay, Warren N. D'Souza, Bo-Rin Park Yoon, Bin Fan, Benjamin M. Alba, Maria Rosalyn Dayao, Melissa Thomas, Khue Dang
Publikováno v:
Journal of Orthopaedic Research.
Designing drugs to treat diseases associated with articular joints, particularly those targeting chondrocytes, is challenging due to unique local environmental constraints including the avascular nature of cartilage, the absence of a closed joint com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c068c3006731a82f743ddf67cf1d28e5
https://doi.org/10.1002/jor.23756
https://doi.org/10.1002/jor.23756
Autor:
Joanne T, Hulme, Warren N, D'Souza, Helen J, McBride, Bo-Rin Park, Yoon, Angela M, Willee, Amy, Duguay, Melissa, Thomas, Bin, Fan, Maria Rosalyn, Dayao, James B, Rottman, Kim, Merriam, Jiansong, Xie, Richard, Smith, Benjamin M, Alba, Ryan B, Case, Khue, Dang, Anielka, Montalvan, Natalia, Grinberg, Hong, Sun, Roy A, Black, Christopher A, Gabel, John E, Sims, Kevin, Moore, Alice, Bakker, Peng, Li
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 36(4)
Designing drugs to treat diseases associated with articular joints, particularly those targeting chondrocytes, is challenging due to unique local environmental constraints including the avascular nature of cartilage, the absence of a closed joint com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::841e1d28a802cc8283200513466ba970
https://pubmed.ncbi.nlm.nih.gov/28971529
https://pubmed.ncbi.nlm.nih.gov/28971529
Autor:
James B. Rottman, Katja Labitzke, Yang Li, Yingcai Wang, Jennifer E. Towne, Warren N. D'Souza, James A. Johnston, Hailing Hsu, Joseph R. Maxwell, Holger Beckmann, Angela Willee, Sharon X. Mu, Peter Jaeckel, Ralf Schwandner, Ming Zhang, Jason Douangpanya
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0180190 (2017)
PLoS ONE, Vol 12, Iss 7, p e0180190 (2017)
Inflammatory bowel disease (IBD) is associated with a loss of intestinal barrier function and dysregulated immune responses. It has been shown that short chain fatty acids (SCFAs) are protective in IBD and that GPR43 mediates the protective effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c24708b94267dea9b312b3659027e8
https://pubmed.ncbi.nlm.nih.gov/28727837
https://pubmed.ncbi.nlm.nih.gov/28727837
Autor:
Stephen M. Hedrick, Warren N. D'Souza
Publikováno v:
The Journal of Immunology. 177:777-781
Factors that influence T cell responses, such as Ag load, APCs, costimulatory molecules, and cytokines, dramatically change during the course of an immune response. We observed that antiviral CD8 T cells were not recruited from circulation simultaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8593428c77ab0324f536456bdb3485
https://doi.org/10.4049/jimmunol.177.2.777
https://doi.org/10.4049/jimmunol.177.2.777
Autor:
Leo Lefrançois, Warren N. D’Souza
Publikováno v:
The Journal of Immunology. 171:5727-5735
Based primarily on in vitro data, IL-2 is believed to be the key cytokine for initiation of the cell cycle of activated T cells. However, the role of IL-2 remains unresolved for T cell responses in vivo. We examined whether the absence of IL-2-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4946ef31c79ddfc64ab2b173782fa868
https://doi.org/10.4049/jimmunol.171.11.5727
https://doi.org/10.4049/jimmunol.171.11.5727
Autor:
Jay Danao, Jim Jiwen Liu, Angela Willee, Warren N. D'Souza, Michael G. Johnson, Sophie Wang, Bettina Van Lengerich, Simon Wong, Peter Fan, Lisa Seitz, Alison L. Budelsky, Julio C. Medina, An-Rong Li, Tassie L. Collins
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(13)
Based on their structural similarity to previously described compound AMG 009, indole-phenyl acetic acids were proposed to be potent dual inhibitors of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2 or DP2) and prostanoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e291b3b5e068e4ba26c9733c67f795fe
https://pubmed.ncbi.nlm.nih.gov/24825301
https://pubmed.ncbi.nlm.nih.gov/24825301
Autor:
Chiung-Fang Chang, Warren N. D'Souza, Gilles Pagès, Stephen M. Hedrick, Jacques Pouysségur, Irene L. Ch’en
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 189(2)
Effective immune responses depend upon appropriate T cell differentiation in accord with the nature of an infectious agent, and the contingency of differentiation depends minimally on TCR, coreceptor, and cytokine signals. In this reverse genetic stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4209b8c7fb8e2829953d9dd6bc425659
https://pubmed.ncbi.nlm.nih.gov/22675204
https://pubmed.ncbi.nlm.nih.gov/22675204