Zobrazeno 1 - 10
of 415
pro vyhledávání: '"Warren M. Grill"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Peripheral neuromodulation has emerged as a powerful modality for controlling physiological functions and treating a variety of medical conditions including chronic pain and organ dysfunction. The underlying complexity of the nonlinear respo
Externí odkaz:
https://doaj.org/article/de41de8328204e9b9d62ce36cf29f835
Autor:
Yuhui Li, Sung-Ho Lee, Chunxiu Yu, Li-Ming Hsu, Tzu-Wen W. Wang, Khoa Do, Hyeon-Joong Kim, Yen-Yu Ian Shih, Warren M. Grill
Publikováno v:
Brain Stimulation, Vol 17, Iss 4, Pp 947-957 (2024)
While deep brain stimulation (DBS) is widely employed for managing motor symptoms in Parkinson's disease (PD), its exact circuit mechanisms remain controversial. To identify the neural targets affected by therapeutic DBS in PD, we analyzed DBS-evoked
Externí odkaz:
https://doaj.org/article/9acafa1d71b34e02b7d157815f6947a4
Autor:
Karthik Kumaravelu, Warren M. Grill
Publikováno v:
Brain Stimulation, Vol 17, Iss 2, Pp 365-381 (2024)
Background: Intracortical microstimulation (ICMS) is used to map neuronal circuitry in the brain and restore lost sensory function, including vision, hearing, and somatosensation. The temporal response of cortical neurons to single pulse ICMS is rema
Externí odkaz:
https://doaj.org/article/5bdc13ed855842db99cbcdccb82d5099
Autor:
Kay Palopoli-Trojani, Stephen L. Schmidt, Karley D. Baringer, Theodore A. Slotkin, Jennifer J. Peters, Dennis A. Turner, Warren M. Grill
Publikováno v:
Brain Stimulation, Vol 16, Iss 6, Pp 1630-1642 (2023)
Background: Traditional deep brain stimulation (DBS) at fixed regular frequencies (>100 Hz) is effective in treating motor symptoms of Parkinson's disease (PD). Temporally non-regular patterns of DBS are a new parameter space that may help increase e
Externí odkaz:
https://doaj.org/article/fd27b5d74b0a4aa7aea40f920da1dea5
Publikováno v:
Brain Stimulation, Vol 16, Iss 6, Pp 1776-1791 (2023)
Background: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation modality that can alter cortical excitability. However, it remains unclear how the subcellular elements of different neuron types are polarized by specific
Externí odkaz:
https://doaj.org/article/2ecc592ced0c4ff6814eb93e1602a854
Autor:
Eric H. Chang, Arielle H. Gabalski, Tomas S. Huerta, Timir Datta-Chaudhuri, Theodoros P. Zanos, Stavros Zanos, Warren M. Grill, Kevin J. Tracey, Yousef Al-Abed
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract The emerging field of bioelectronic medicine (BEM) is poised to make a significant impact on the treatment of several neurological and inflammatory disorders. With several BEM therapies being recently approved for clinical use and others in
Externí odkaz:
https://doaj.org/article/bf9dae8608184cdb9541838584ab39b1
Publikováno v:
Journal of NeuroEngineering and Rehabilitation, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Background Electrical nerve conduction block has great potential for treatment of disease through reversible and local inactivation of somatic and autonomic nerves. However, the relatively high energy requirements and the presence of undesir
Externí odkaz:
https://doaj.org/article/a416221293ee45a3bd4ae536d54e2dec
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-26 (2023)
Abstract Background Reduced heart rate (HR) during vagus nerve stimulation (VNS) is associated with therapy for heart failure, but stimulation frequency and amplitude are limited by patient tolerance. An understanding of physiological responses to pa
Externí odkaz:
https://doaj.org/article/4f23645a83d047c29dbf7a6ffc6ab302
Publikováno v:
Brain Stimulation, Vol 15, Iss 5, Pp 1040-1047 (2022)
Background and objectives: The goal of this review is to describe the general features, mechanisms, technical recording factors, and clinical applications of brain evoked potentials (EPs) generated by deep brain stimulation (DBS) for Parkinson's dise
Externí odkaz:
https://doaj.org/article/82ce22c9bbe948779429936f5ad33bcc
Publikováno v:
Brain Stimulation, Vol 15, Iss 5, Pp 1051-1062 (2022)
Background: Temporal patterns of stimulation represent a novel dimension for improving the efficacy of spinal cord stimulation to treat chronic neuropathic pain. Objective: We hypothesized that nonregular temporal patterns of stimulation designed usi
Externí odkaz:
https://doaj.org/article/19f3911c44e4487b93279f1751628f05