Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Warren J. Alilain"'
Autor:
Lindsey R. Conroy, Harrison A. Clarke, Derek B. Allison, Samuel Santos Valenca, Qi Sun, Tara R. Hawkinson, Lyndsay E. A. Young, Juanita E. Ferreira, Autumn V. Hammonds, Jaclyn B. Dunne, Robert J. McDonald, Kimberly J. Absher, Brittany E. Dong, Ronald C. Bruntz, Kia H. Markussen, Jelena A. Juras, Warren J. Alilain, Jinze Liu, Matthew S. Gentry, Peggi M. Angel, Christopher M. Waters, Ramon C. Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Matrix assisted laser desorption/ionization imaging has greatly improved our understanding of spatial biology, however a robust bioinformatic pipeline for data analysis is lacking. Here, we demonstrate the application of high-dimensionality
Externí odkaz:
https://doaj.org/article/b0ff5fe6b39c436785307a404579d8e4
Publikováno v:
Neurotrauma Reports, Vol 2, Iss 1, Pp 343-353 (2021)
Intermittent hypoxia treatment (IH) has been shown to improve respiratory function in both pre-clinical animal models and human subjects following spinal cord injury (SCI), historically consisting of alternating and equal intervals of hypoxic and nor
Externí odkaz:
https://doaj.org/article/e4ff1b9b88c34596a4ed1c745ea68b9d
Publikováno v:
Frontiers in Systems Neuroscience, Vol 13 (2020)
Respiratory motor failure is the leading cause of death in spinal cord injury (SCI). Cervical injuries disrupt connections between brainstem neurons that are the primary source of excitatory drive to respiratory motor neurons in the spinal cord and t
Externí odkaz:
https://doaj.org/article/9c7b9afd5010409f9e95366bb1b57a7e
Autor:
Philippa M. Warren, Stephanie C. Steiger, Thomas E. Dick, Peter M. MacFarlane, Warren J. Alilain, Jerry Silver
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Respiratory failure is one of the leading causes of death following spinal cord injury and it is unclear if normal respiratory motor activity can be recovered after chronic injury-induced paralysis. Here, authors show that treatment with chondroitina
Externí odkaz:
https://doaj.org/article/855272d6d1de435e917538c553e07920
A Latent Propriospinal Network Can Restore Diaphragm Function after High Cervical Spinal Cord Injury
Autor:
Jared M. Cregg, Kevin A. Chu, Lydia E. Hager, Rachel S.J. Maggard, Daimen R. Stoltz, Michaela Edmond, Warren J. Alilain, Polyxeni Philippidou, Lynn T. Landmesser, Jerry Silver
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 654-665 (2017)
Spinal cord injury (SCI) above cervical level 4 disrupts descending axons from the medulla that innervate phrenic motor neurons, causing permanent paralysis of the diaphragm. Using an ex vivo preparation in neonatal mice, we have identified an excita
Externí odkaz:
https://doaj.org/article/994ec695c1454270848206c7b3bfa16f
Autor:
Emily E Huffman, Brittany E Dong, Harrison A Clarke, Lyndsay E A Young, Matthew S Gentry, Derek B Allison, Ramon C Sun, Christopher M Waters, Warren J Alilain
Publikováno v:
Brain Communications. 5
High-cervical spinal cord injury often disrupts respiratory motor pathways and disables breathing in the affected population. Moreover, cervically injured individuals are at risk for developing acute lung injury, which predicts substantial mortality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c1ded65dbfdd304fb66d153eb2fefa5
https://doi.org/10.1093/braincomms/fcad091
https://doi.org/10.1093/braincomms/fcad091
Autor:
Lyndsay E A Young, Lindsey R Conroy, Harrison A Clarke, Tara R Hawkinson, Kayli E Bolton, William C Sanders, Josephine E Chang, Madison B Webb, Warren J Alilain, Craig W Vander Kooi, Richard R Drake, Douglas A Andres, Tom C Badgett, Lars M Wagner, Derek B Allison, Ramon C Sun, Matthew S Gentry
Publikováno v:
EMBO Molecular Medicine. 14
Glycogen dysregulation is a hallmark of aging, and aberrant glycogen drives metabolic reprogramming and pathogenesis in multiple diseases. However, glycogen heterogeneity in healthy and diseased tissues remains largely unknown. Herein, we describe a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89790a9115af5c70b57f47ea06c209b7
https://doi.org/10.15252/emmm.202216029
https://doi.org/10.15252/emmm.202216029
Autor:
Warren J. Alilain, Aaron Silverstein
Publikováno v:
Neurotrauma Reports
Intermittent hypoxia treatment (IH) has been shown to improve respiratory function in both pre-clinical animal models and human subjects following spinal cord injury (SCI), historically consisting of alternating and equal intervals of hypoxic and nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e7c5dbf1df7afbe042497a74c27a7a
https://doi.org/10.1089/neur.2021.0004
https://doi.org/10.1089/neur.2021.0004
Autor:
Chase E. Taylor, Laura E. Mendenhall, Michael D. Sunshine, Jessica N. Wilson, Chris M. Calulot, Lance A. Johnson, Warren J. Alilain
Ventilation is regulated across many systems, with respiratory rhythm formation occurring in the brainstem but modulated in response to: chemoreception, respiratory muscle afferents, and volitional control. Alterations within any of these systems may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c226f9ab1730e2ffd4c9297de5b1e14
https://doi.org/10.1101/2022.08.03.502692
https://doi.org/10.1101/2022.08.03.502692
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c513fbebf803b933eef61bacf2d67c0e
https://doi.org/10.1096/fasebj.2022.36.s1.r3563
https://doi.org/10.1096/fasebj.2022.36.s1.r3563