Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Warren J Strittmatter"'
Autor:
Anna C Need, Dongliang Ge, Michael E Weale, Jessica Maia, Sheng Feng, Erin L Heinzen, Kevin V Shianna, Woohyun Yoon, Dalia Kasperaviciūte, Massimo Gennarelli, Warren J Strittmatter, Cristian Bonvicini, Giuseppe Rossi, Karu Jayathilake, Philip A Cola, Joseph P McEvoy, Richard S E Keefe, Elizabeth M C Fisher, Pamela L St Jean, Ina Giegling, Annette M Hartmann, Hans-Jürgen Möller, Andreas Ruppert, Gillian Fraser, Caroline Crombie, Lefkos T Middleton, David St Clair, Allen D Roses, Pierandrea Muglia, Clyde Francks, Dan Rujescu, Herbert Y Meltzer, David B Goldstein
Publikováno v:
PLoS Genetics, Vol 5, Iss 2, p e1000373 (2009)
We report a genome-wide assessment of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) in schizophrenia. We investigated SNPs using 871 patients and 863 controls, following up the top hits in four independent cohorts comprising
Externí odkaz:
https://doaj.org/article/c19e84d31375449d8e0177d2a66e2fc4
Autor:
Mirta Mihovilovic, Jennifer B. Robinette, Robert M. DeKroon, Patrick M. Sullivan, Warren J. Strittmatter
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 4, Pp 806-815 (2007)
Withdrawing growth factors or serum from endothelial cells leads to the activation of effector caspases 3 and 7, resulting in apoptotic cell death. HDL protects against caspase induction through sphingosine-1-phosphate (S1P) receptors. This anti-casp
Externí odkaz:
https://doaj.org/article/2a308f6569e44fea8c5c86f178d58c87
Autor:
Robert M. DeKroon, Mirta Mihovilovic, Zoe V. Goodger, Jennifer B. Robinette, Patrick M. Sullivan, Ann M. Saunders, Warren J. Strittmatter
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 8, Pp 1566-1573 (2003)
Endothelial cell apoptosis can be initiated by withdrawing growth factors or serum, and is inhibited by HDL. Our results show that the total lipoprotein population from apolipoprotein E 4/4 (APOE4/4) sera is less anti-apoptotic than total lipoprotein
Externí odkaz:
https://doaj.org/article/fca56956896c47699c833c73e329d636
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d0a5ebe1ff136ff8ed71ce46988ed75
https://doi.org/10.1002/alz.039922
https://doi.org/10.1002/alz.039922
Publikováno v:
Journal of Alzheimer's Disease
Background T3D-959 is a chemically unique, brain penetrant, dual PPAR delta/gamma agonist with 15-fold higher PPAR delta selectivity. Ubiquitous brain expression of PPAR delta, its critical role in regulating glucose and lipid metabolism, and the Alz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8fcd847b9b8eb1ac591b6315e48fe1
https://pubmed.ncbi.nlm.nih.gov/31884472
https://pubmed.ncbi.nlm.nih.gov/31884472
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::536a1f8378022f4f324908b9baf85f26
https://doi.org/10.1016/j.jalz.2018.06.2399
https://doi.org/10.1016/j.jalz.2018.06.2399
Autor:
Nobutaka Fujii, Yoshitaka Nagai, Tatsushi Toda, Shinya Oishi, Keiji Wada, Warren J. Strittmatter, H. Akiko Popiel, Toshihide Takeuchi, James R. Burke
Publikováno v:
Journal of Amino Acids
Misfolding and abnormal aggregation of proteins in the brain are implicated in the pathogenesis of various neurodegenerative diseases including Alzheimer's, Parkinson's, and the polyglutamine (polyQ) diseases. In the polyQ diseases, an abnormally exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046b88eaeb6b7bd970109f6427ec5354
https://doi.org/10.4061/2011/265084
https://doi.org/10.4061/2011/265084
Autor:
Jon P. Gockerman, Joseph O. Moore, Mirta Mihovilovic, Karen M. Bond, Louis F. Diehl, Marc C. Levesque, JB Weinberg, Alicia D. Volkheimer, Youwei Chen, David A. Rizzieri, Robert M. DeKroon, Ning Jiang, Warren J. Strittmatter, C. M. De Castro
Publikováno v:
Leukemia. 22:2184-2192
Survival of chronic lymphocytic leukemia (CLL) cells requires sustained activation of the antiapoptotic PI-3-K/Akt pathway, and many therapies for CLL cause leukemia cell death by triggering apoptosis. Blood lipoprotein particles are either pro- or a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c475755b3b95f88ba2c0c79d5dc4a19c
https://doi.org/10.1038/leu.2008.241
https://doi.org/10.1038/leu.2008.241
Autor:
Vittorio Gentile, James R. Burke, Warren J. Strittmatter, Arthur J.L. Cooper, Kwan-Fu Rex Sheu, Gianfranco Peluso, John P. Blass
Publikováno v:
Journal of Neurochemistry. 72:889-899
At least eight neurodegenerative diseases, including Huntington disease, are caused by expansions in (CAG)n repeats in the affected gene and by an increase in the size of the corresponding polyglutamine domain in the expressed protein. A hallmark of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe7bb84ba2ab240214ac3be5ec9aa28
https://doi.org/10.1046/j.1471-4159.1999.0720889.x
https://doi.org/10.1046/j.1471-4159.1999.0720889.x
Autor:
John F. Ervin, Cristina Osorio, Oscar Alzate, Patrick Sullivan, Brian E. Mace, Dong Ning He, Warren J. Strittmatter
Publikováno v:
Neurobiology of Aging. 28:1853-1862
Mortalin is a chaperone protein associated with cell survival, stress response, intracellular trafficking, control of cell proliferation, mitochondrial biogenesis, and cell fate determination. Human APOE targeted replacement (TR) mice have been used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587f8f14821d71c389413934f05e90ea
https://doi.org/10.1016/j.neurobiolaging.2006.08.011
https://doi.org/10.1016/j.neurobiolaging.2006.08.011