Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Warren Heideman"'
Publikováno v:
Journal of Developmental Biology, Vol 1, Iss 2, Pp 112-125 (2013)
Zebrafish (Danio rerio) are an excellent vertebrate model for studying heart development, regeneration and cardiotoxicity. Zebrafish embryos exposed during the temporal window of epicardium development to the aryl hydrocarbon receptor (AHR) agonist 2
Externí odkaz:
https://doaj.org/article/ff186757d85f4193a10f90bf5bd9f58b
Publikováno v:
BioTechniques, Vol 40, Iss 6, Pp 728-734 (2006)
Externí odkaz:
https://doaj.org/article/4a09e895436446678b384d21d71e630a
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28020 (2011)
The toxicity by 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) is thought to be caused by activation of the aryl hydrocarbon receptor (AHR). However, our understanding of how AHR activation by TCDD leads to toxic effects is poor. Ideally we would like to
Externí odkaz:
https://doaj.org/article/4285c212f3d64a8484f04589f9158062
Publikováno v:
Aquatic Toxicology. 164:52-60
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD or dioxin) disrupts craniofacial development in zebrafish larvae. However, the cellular changes responsible for the decreased jaw size remain poorly understood. We show that smaller jaw size is due to a decre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737e2306332f14ec45e01b83475f9d93
https://doi.org/10.1016/j.aquatox.2015.04.005
https://doi.org/10.1016/j.aquatox.2015.04.005
Publikováno v:
Molecular and Cellular Endocrinology. 398:36-41
Dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDD) is an aryl hydrocarbon receptor (AHR) agonist, an endocrine disruptor, and a potent global pollutant. TCDD exposure is associated with diseases of almost every organ system, and its toxicity is highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e75dfd9ad1a925e1352c477e2ba10b0
https://doi.org/10.1016/j.mce.2014.08.011
https://doi.org/10.1016/j.mce.2014.08.011
Publikováno v:
Journal of Developmental Biology, Vol 1, Iss 2, Pp 112-125 (2013)
Journal of developmental biology
Journal of developmental biology
Zebrafish (Danio rerio) are an excellent vertebrate model for studying heart development, regeneration and cardiotoxicity. Zebrafish embryos exposed during the temporal window of epicardium development to the aryl hydrocarbon receptor (AHR) agonist 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd158c6c9910df6f9f9afa75d192f0c
http://www.mdpi.com/2221-3759/1/2/112
http://www.mdpi.com/2221-3759/1/2/112
Publikováno v:
Molecular Pharmacology. 84:353-360
Activation of the transcription factor aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) prevents the formation of the epicardium and leads to severe heart malformations in developing zebrafish (Danio rerio). The downstream gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def17c900c23a265cbf10d9a580b019e
https://doi.org/10.1124/mol.113.086413
https://doi.org/10.1124/mol.113.086413
Publikováno v:
Journal of Proteome Research. 12:3093-3103
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent environmental pollutant and teratogen that produces cardiac toxicity in the developing zebrafish. Here we adopted a label free quantitative proteomic approach based on normalized spectral abu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ab889ae110baa876983e3eb671443f
https://doi.org/10.1021/pr400312u
https://doi.org/10.1021/pr400312u
Autor:
Denise J. Schwahn, Joel A. Pedersen, Richard E. Peterson, Ofek Bar-Ilan, Connie Chuang, Sanjay B. Joshi, Warren Heideman, Sarah Yang, Robert J. Hamers
Publikováno v:
Environmental Science & Technology. 47:4726-4733
Photoactivation of titanium dioxide nanoparticles (TiO2NPs) can produce reactive oxygen species (ROS). Over time, this has the potential to produce cumulative cellular damage. To test this, we exposed zebrafish (Danio rerio) to two commercial TiO2NP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5253a0f767d7220cc0addc80cc74c5
https://doi.org/10.1021/es304514r
https://doi.org/10.1021/es304514r
Publikováno v:
Toxicological Sciences. 131:558-567
Embryonic exposure to the environmental contaminant and aryl hydrocarbon receptor agonist, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin), disrupts cardiac development and function in fish, birds, and mammals. In zebrafish, the temporal window of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473a1911de6a52bc6de4471986073e3a
https://doi.org/10.1093/toxsci/kfs301
https://doi.org/10.1093/toxsci/kfs301