Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Warren D Heston"'
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-8 (2024)
Abstract Background The current generation of radiolabeled PSMA-targeting therapeutic agents is limited by prominent salivary gland binding, which results in dose-limiting xerostomia from radiation exposure. JB-1498 is a urea-based small molecule wit
Externí odkaz:
https://doaj.org/article/a2cf72a7ba264a219fd6e22305160176
Autor:
Payel Chatterjee, Gaurav S Choudhary, Arishya Sharma, Kamini Singh, Warren D Heston, Jay Ciezki, Eric A Klein, Alexandru Almasan
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60408 (2013)
Exposure to genotoxic agents, such as irradiation produces DNA damage, the toxicity of which is augmented when the DNA repair is impaired. Poly (ADP-ribose) polymerase (PARP) inhibitors were found to be "synthetic lethal" in cells deficient in BRCA1
Externí odkaz:
https://doaj.org/article/c164bf40b7d143efa176009e338872bc
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce6bc31dbf508f0a67df951fab90a342
https://doi.org/10.1007/s00259-023-06265-6
https://doi.org/10.1007/s00259-023-06265-6
Autor:
Alexandru Almasan, Eric A. Klein, Junran Zhang, Cristina Magi-Galluzzi, Warren D. Heston, Xiahui Xiong, Turkeyah Alswillah, Gaurav S. Choudhary, Payel Chatterjee
The proportion of cells in the different phases of the cell cycle at 24 and 48 h following IR, administered alone or in combination with PARPi, determined by flow cytometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e39f439b6bcaeaa6088d2a0be1b8020
https://doi.org/10.1158/1535-7163.22502281.v1
https://doi.org/10.1158/1535-7163.22502281.v1
Autor:
Alexandru Almasan, Eric A. Klein, Junran Zhang, Cristina Magi-Galluzzi, Warren D. Heston, Xiahui Xiong, Turkeyah Alswillah, Gaurav S. Choudhary, Payel Chatterjee
TMPRSS2/ERG inhibits Ser2056 DNA-PKcs phosphorylation. Confocal immunostaining for phospho-DNA-PKcs Ser2056 at indicated times following IR in PC3 with or without expression of the TMPRSS2-ERG fusion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e87687dd7b241469f83ab070f1b0281
https://doi.org/10.1158/1535-7163.22502287
https://doi.org/10.1158/1535-7163.22502287
Autor:
Michel Sadelain, Jason A. Koutcher, Steven M. Larson, Isabelle Rivière, Warren D. Heston, Simon J. Hall, Ian M. Buchanan, Joseph R. Osborne, Clay Lyddane, Jolanta Stefanski, Matthias Stephan, Xiao-Song Zhong, Renier Brentjens, Michael C. Gong, Aurore Saudemont, Gertrude Gunset, Elmer Santos, Waleed Hassen, Terence P.F. Gade
Supplementary Figure 1 from Targeted Elimination of Prostate Cancer by Genetically Directed Human T Lymphocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68782119fc99d91c549ae6a0c332f63a
https://doi.org/10.1158/0008-5472.22363475
https://doi.org/10.1158/0008-5472.22363475
Autor:
Michel Sadelain, Jason A. Koutcher, Steven M. Larson, Isabelle Rivière, Warren D. Heston, Simon J. Hall, Ian M. Buchanan, Joseph R. Osborne, Clay Lyddane, Jolanta Stefanski, Matthias Stephan, Xiao-Song Zhong, Renier Brentjens, Michael C. Gong, Aurore Saudemont, Gertrude Gunset, Elmer Santos, Waleed Hassen, Terence P.F. Gade
Supplementary Figure 2 from Targeted Elimination of Prostate Cancer by Genetically Directed Human T Lymphocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9e8a0bd1917b513c1d6832ed3b6949
https://doi.org/10.1158/0008-5472.22363472
https://doi.org/10.1158/0008-5472.22363472
Autor:
Michel Sadelain, Jason A. Koutcher, Steven M. Larson, Isabelle Rivière, Warren D. Heston, Simon J. Hall, Ian M. Buchanan, Joseph R. Osborne, Clay Lyddane, Jolanta Stefanski, Matthias Stephan, Xiao-Song Zhong, Renier Brentjens, Michael C. Gong, Aurore Saudemont, Gertrude Gunset, Elmer Santos, Waleed Hassen, Terence P.F. Gade
The genetic transfer of antigen receptors is a powerful approach to rapidly generate tumor-specific T lymphocytes. Unlike the physiologic T-cell receptor, chimeric antigen receptors (CARs) encompass immunoglobulin variable regions or receptor ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026448469b8a17efd485d527031e36db
https://doi.org/10.1158/0008-5472.c.6493727
https://doi.org/10.1158/0008-5472.c.6493727
Autor:
Warren D. Heston
Publikováno v:
Urology. 145:329-330
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5789e0c2b0085ce89656f2fba89bd92c
https://doi.org/10.1016/j.urology.2020.04.027
https://doi.org/10.1016/j.urology.2020.04.027
Autor:
Steve S. Huang, Warren D. Heston
Publikováno v:
Theranostics
Prostate-specific membrane antigen (PSMA) continues to be an active biomarker for small-molecule PSMA-targeted imaging and therapeutic agents for prostate cancer and various non-prostatic tumors that are characterized by PSMA expression on their neov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272d8100f75799314461273acc58d025
https://doi.org/10.7150/thno.20284
https://doi.org/10.7150/thno.20284