Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Warren Chew"'
Autor:
Warren Chew, John Hamilton Sellstedt, Sam Tadayon, Razzak Noureldin, Jerry Sun, Wang Youchu, Galante Rocco John, Maria Papamichelakis, Sylvain Daigneault
Publikováno v:
Organic Process Research & Development. 12:1253-1260
A suitable process for the preparation of kilogram quantities of a TNF-α converting enzyme (TACE) inhibitor (WAY-281418) was developed using isatin 13 as starting material and an efficient coupling step for the formation of sulfonamide 8 in a 15% ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eca0e41cd50a89047eb316b4bacf9f00
https://doi.org/10.1021/op800090s
https://doi.org/10.1021/op800090s
Publikováno v:
Tetrahedron Letters. 38:5411-5414
A conformationally stable, acridone-based linker (1) was synthesized and attached to p-tert-butylcalix[8]arene (2) to form the novel 1,4-bridged calix[8]arene derivative 3. The structural assignment of 3 was based on its MS and high-field NMR data an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6f8838c0f4ec966a4d74f87fd015575
https://doi.org/10.1016/s0040-4039(97)01202-1
https://doi.org/10.1016/s0040-4039(97)01202-1
Autor:
David N. Harpp, Warren Chew
Publikováno v:
Sulfur reports. 15:1-39
This review is not meant to be exhaustive. Several reviews on the synthesis, physical properties, and reactivity of thiiranes have appeared in the past 17 years. This effort is to update previous work on thiiranes with an emphasis on research reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::454008f764d4160263f89ef21ac89551
https://doi.org/10.1080/01961779308050628
https://doi.org/10.1080/01961779308050628
Publikováno v:
The Journal of Organic Chemistry. 58:4398-4404
Several novel 9-fluorenones were synthesized and were used as precursors in an attempt to prepare unique substituted 3',3'-dichlorospiro[fluorene-9,2'-thiiranes]. Several of the thiiranes were unstable and desulfurized during their preparation (7a-d,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::503ba21ac5b0433b441e6753104d6f72
https://doi.org/10.1021/jo00068a039
https://doi.org/10.1021/jo00068a039
Autor:
David N. Harpp, Warren Chew
Publikováno v:
The Journal of Organic Chemistry. 58:4405-4410
Kinetic studies on the thermal decomposition of 2,2-dichloro-3-(9-fluorenylidene)thiirane in 12 solvents have been investigated in detail. A two-term rate equation has been derived to account for the overall rate changes. Both a uni- and bimolecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a2b3587fa22ec15bccda59514f4ab93
https://doi.org/10.1021/jo00068a040
https://doi.org/10.1021/jo00068a040
Publikováno v:
ChemInform. 24
Several novel 9-fluorenones were synthesized and were used as precursors in an attempt to prepare unique substituted 3',3'-dichlorospiro[fluorene-9,2'-thiiranes]. Several of the thiiranes were unstable and desulfurized during their preparation (7a-d,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff25424e239c4936fa1d8c2f43526d77
https://doi.org/10.1002/chin.199349153
https://doi.org/10.1002/chin.199349153
Autor:
David N. Harpp, Warren Chew
Publikováno v:
ChemInform. 26
This review is not meant to be exhaustive. Several reviews on the synthesis, physical properties, and reactivity of thiiranes have appeared in the past 17 years. This effort is to update previous work on thiiranes with an emphasis on research reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0001df75255194684445040c2ce84e2a
https://doi.org/10.1002/chin.199517285
https://doi.org/10.1002/chin.199517285
Autor:
David N. Harpp, Warren Chew
Publikováno v:
Tetrahedron Letters. 33:45-48
2,2 Dichloro-3-[9-fluorenyl] episulfide (2) slowly extrudes sulfur when treated thermally. The reaction generally follows unimolecular behavior but at higher concentrations in decalin, toluene and p-xylene, a bimolecular pathway is demonstrated. Kine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43402db16d753531f2bf077e375f6f6d
https://doi.org/10.1016/s0040-4039(00)77669-6
https://doi.org/10.1016/s0040-4039(00)77669-6
Autor:
Youchu Wang, Maria Papamichelakis, Warren Chew, John Sellstedt, Razzak Noureldin, Sam Tadayon, Sylvain Daigneault, Rocco J. Galante, Jerry Sun
Publikováno v:
Organic Process Research & Development; Nov2008, Vol. 12 Issue 6, p1253-1260, 8p
Publikováno v:
Carbohydrate Research. 189:135-148
In the chromate oxidation of a partially acylated sugar derivative to form the corresponding uronic acid, acyl migration to the primary alcohol group is a frequent cause of interference. In contrast to more commonly employed ester substituents, the O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10254c367318025a4f549608aa2a11f9
https://doi.org/10.1016/0008-6215(89)84092-3
https://doi.org/10.1016/0008-6215(89)84092-3