Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Warren Hurlburt"'
Autor:
Joan M. Carboni, Jeffrey Jackson, Friedrich G. Finckenstein, Tai W. Wong, Rolf-Peter Ryseck, Craig Fairchild, Zhenhao Qi, Dharmesh Patel, John Cogswell, Warren Hurlburt, Karen A. Reeves, Stephen Hillerman, Ann Greer, Han Chang, Fei Huang
Supplementary Tables S1-S4. Supplementary Table S1: Association of gene mutations, IRS2 copy number gain, and gene expression level with in vitro sensitivity to BMS-754807 in 60 CRC cell lines. Supplementary Table S2: The relationship between KRAS, B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf361093d6982b4e2b58d163680e344
https://doi.org/10.1158/1535-7163.22503652.v1
https://doi.org/10.1158/1535-7163.22503652.v1
Autor:
Joan M. Carboni, Jeffrey Jackson, Friedrich G. Finckenstein, Tai W. Wong, Rolf-Peter Ryseck, Craig Fairchild, Zhenhao Qi, Dharmesh Patel, John Cogswell, Warren Hurlburt, Karen A. Reeves, Stephen Hillerman, Ann Greer, Han Chang, Fei Huang
Supplementary Figures S1-S5. Supplementary Figure S1. Similarity of CNV profiles are seen from both CRC cell lines and CRC primary tumor samples with highlight on chromosome 13 copy number gain. Supplementary Figure S2: The RNA expression levels comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2952872ef51281f0ac1ebaa8a0d3bbc8
https://doi.org/10.1158/1535-7163.22503658.v1
https://doi.org/10.1158/1535-7163.22503658.v1
Autor:
Marco M. Gottardis, Ricardo M. Attar, Robert Kramer, Dolatrai Vyas, George Trainor, Aixin Li, Krista Menard, Lorell Discenza, Cliff Chen, Janet Dell-John, Glenn H. Cantor, Carolyn Cao, Stephen Hillerman, Warren Hurlburt, Ann Greer, Francis Lee, Zheng Yang, Mark Wittman, Joan M. Carboni
Legends for Supplementary Figures 1-2, Tables 1-6 from BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2c544b8ee16f58175edab160b033f4
https://doi.org/10.1158/1535-7163.22485218
https://doi.org/10.1158/1535-7163.22485218
Autor:
Marco M. Gottardis, Ricardo M. Attar, Robert Kramer, Dolatrai Vyas, George Trainor, Aixin Li, Krista Menard, Lorell Discenza, Cliff Chen, Janet Dell-John, Glenn H. Cantor, Carolyn Cao, Stephen Hillerman, Warren Hurlburt, Ann Greer, Francis Lee, Zheng Yang, Mark Wittman, Joan M. Carboni
Supplementary Tables 1-6 from BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb573ea3b1cac91d2db653d78a7f6e8
https://doi.org/10.1158/1535-7163.22485209.v1
https://doi.org/10.1158/1535-7163.22485209.v1
Autor:
Marco M. Gottardis, Ricardo M. Attar, Robert Kramer, Dolatrai Vyas, George Trainor, Aixin Li, Krista Menard, Lorell Discenza, Cliff Chen, Janet Dell-John, Glenn H. Cantor, Carolyn Cao, Stephen Hillerman, Warren Hurlburt, Ann Greer, Francis Lee, Zheng Yang, Mark Wittman, Joan M. Carboni
Supplementary Figure 1 from BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebdda8326e710242923e515affb3ab3
https://doi.org/10.1158/1535-7163.22485215
https://doi.org/10.1158/1535-7163.22485215
Autor:
Marco M. Gottardis, Ricardo M. Attar, Robert Kramer, Dolatrai Vyas, George Trainor, Aixin Li, Krista Menard, Lorell Discenza, Cliff Chen, Janet Dell-John, Glenn H. Cantor, Carolyn Cao, Stephen Hillerman, Warren Hurlburt, Ann Greer, Francis Lee, Zheng Yang, Mark Wittman, Joan M. Carboni
BMS-754807 is a potent and reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases (Ki, in vitro, including mesenchymal (Ewing's, rhabdomyosarcoma, neuroblastoma, and liposarcoma), epithelial (breast, lung, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc63230107c1e05a299e1da8aaf1d21
https://doi.org/10.1158/1535-7163.c.6531836.v1
https://doi.org/10.1158/1535-7163.c.6531836.v1
Autor:
Marco M. Gottardis, Ricardo M. Attar, Robert Kramer, Dolatrai Vyas, George Trainor, Aixin Li, Krista Menard, Lorell Discenza, Cliff Chen, Janet Dell-John, Glenn H. Cantor, Carolyn Cao, Stephen Hillerman, Warren Hurlburt, Ann Greer, Francis Lee, Zheng Yang, Mark Wittman, Joan M. Carboni
Supplementary Figure 2 from BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a92fde8b5e3b4189da038ca18d952d52
https://doi.org/10.1158/1535-7163.22485212.v1
https://doi.org/10.1158/1535-7163.22485212.v1
Autor:
Joan M. Carboni, Marco M. Gottardis, Friedrich Graf Finckenstein, Joseph Fargnoli, Han Chang, Stephen Hillerman, Karen A. Reeves, Ann Greer, Warren Hurlburt, Fei Huang
Agents targeting insulin-like growth factor-I receptor (IGF-IR), including antibodies and small-molecule inhibitors, are currently in clinical development for the treatment of cancers including sarcoma. However, development of resistance is a common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df3de15f1f66352b33605d244cb2df4
https://doi.org/10.1158/0008-5472.c.6501168
https://doi.org/10.1158/0008-5472.c.6501168
Autor:
Joan M. Carboni, Ashok Dongre, Ricardo M. Attar, Lee Helman, Edwin Clark, Marco M. Gottardis, Francis Y. Lee, Aixin Li, Douglas Robinson, Jiwen Chen, Karen Reeves, Gayle M. Wittenberg, Rameh Hafezi, Xia Han, Warren Hurlburt, Ann Greer, Fei Huang
Supplementary Figures 1-8 from The Mechanisms of Differential Sensitivity to an Insulin-like Growth Factor-1 Receptor Inhibitor (BMS-536924) and Rationale for Combining with EGFR/HER2 Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42474490c8ed6a3b377f9e7b43d1f72d
https://doi.org/10.1158/0008-5472.22376792.v1
https://doi.org/10.1158/0008-5472.22376792.v1
Autor:
Joan M. Carboni, Marco M. Gottardis, Friedrich Graf Finckenstein, Joseph Fargnoli, Han Chang, Stephen Hillerman, Karen A. Reeves, Ann Greer, Warren Hurlburt, Fei Huang
Supplementary Figures 1-10, Tables 1-5 from Differential Mechanisms of Acquired Resistance to Insulin-like Growth Factor-I Receptor Antibody Therapy or to a Small-Molecule Inhibitor, BMS-754807, in a Human Rhabdomyosarcoma Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a702b329984502642149893f05077804
https://doi.org/10.1158/0008-5472.22385256.v1
https://doi.org/10.1158/0008-5472.22385256.v1