Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Warren, Mason"'
Autor:
Carine Jiguet-Jiglaire, Sebastien Boissonneau, Emilie Denicolai, Victoria Hein, Romain Lasseur, Josep Garcia, Sylvie Romain, Romain Appay, Thomas Graillon, Warren Mason, Antoine F. Carpentier, Alba A. Brandes, L.’Houcine Ouafik, Wolfgang Wick, Ania Baaziz, Julien P. Gigan, Rafael J. Argüello, Dominique Figarella-Branger, Olivier Chinot, Emeline Tabouret
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract We previously identified matrix metalloproteinase 2 (MMP2) and MMP9 plasma levels as candidate biomarkers of bevacizumab activity in patients with recurrent glioblastoma. The aim of this study was to assess the predictive value of MMP2 and M
Externí odkaz:
https://doaj.org/article/699a6ad92f1a400fa0b9d1249588ad83
Autor:
Derek S. Tsang, MD, MSc, Mohammad M. Khandwala, MD, Zhihui Amy Liu, PhD, Nadine Richard, PhD, Gerald Shen, HBSc, Angela Sekely, MA, Lori J. Bernstein, PhD, Rebecca Simpson, Warren Mason, MD, Caroline Chung, MD, MSc, Fabio Ynoe de Moraes, MD, PhD, Louise Murray, MBChB, PhD, David Shultz, MD, PhD, Normand Laperriere, MD, Barbara-Ann Millar, MBChB, Kim Edelstein, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 7, Iss 6, Pp 101028- (2022)
Purpose: The contributory effects of radiation dose to different brain regions on neurocognitive performance after radiation therapy (RT) for primary brain tumors is not well known. Methods and Materials: In this retrospective cohort study, 30 patien
Externí odkaz:
https://doaj.org/article/afd7b90898fe4123aaa31c37b07ddf17
Autor:
David Mills, Hui Gan, Jeffrey Raizer, Patrick Yung Wen, Warren Mason, John DeGroot, Valerie Donnet, Mona El-Hashimy, Mark Rosenthal, Paul M Clement, Mario Campone, Miguel J Gil-Gil, Olivier Chinot, Ahmed Idbaih, Estela Pineda
Publikováno v:
ESMO Open, Vol 5, Iss 4 (2020)
Background Glioblastoma relapse is associated with activation of phosphatidylinositol 3-kinase (PI3K) signalling pathway. In preclinical studies, the pan-PI3K inhibitor buparlisib showed antitumour activity in glioma models.Methods This was a two-par
Externí odkaz:
https://doaj.org/article/9958bcd5cebc4f3d938a04ffd0410a75
Autor:
David Mills, Patrick Yung Wen, Jordi A Rodon, Warren Mason, Joseph T Beck, John DeGroot, Valerie Donnet, Mona El-Hashimy, Mark Rosenthal
Publikováno v:
ESMO Open, Vol 5, Iss 4 (2020)
Background Most glioblastoma tumours exhibit intrinsic phosphatidylinositol 3-kinase (PI3K) pathway activation. Preclinical in vitro and in vivo models suggest that buparlisib (an oral pan-PI3K inhibitor) can have an effect on glioblastoma directly a
Externí odkaz:
https://doaj.org/article/745fb5b4e852483e86d0296058aea66b
Data from Tissue 2-Hydroxyglutarate as a Biomarker for Isocitrate Dehydrogenase Mutations in Gliomas
Autor:
Eric X. Chen, Gelareh Zadeh, Kenneth D. Aldape, Warren Mason, Farshad Nassiri, Wenjiang Zhang, Romina Nejad, Hao-Wen Sim
Purpose:Isocitrate dehydrogenase (IDH) mutations are common in low-grade gliomas and the IDH mutation status is now integrated into the WHO classification of gliomas. IDH mutations lead to preferential accumulation of the R- relative to the S-enantio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479328a3f473d66d8076c0afbe04c970
https://doi.org/10.1158/1078-0432.c.6528165.v1
https://doi.org/10.1158/1078-0432.c.6528165.v1
Autor:
Eric X. Chen, Gelareh Zadeh, Kenneth D. Aldape, Warren Mason, Farshad Nassiri, Wenjiang Zhang, Romina Nejad, Hao-Wen Sim
supplementary Figure 1, Tables 1-3 Figure 1. Representative chromatograms from IDH wild type and IDH mutant glioma samples Table 1. Individual R- and S-2-HG concentrations in all patients Table 2. Individual R- and S-2-HG concentrations from patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b8f8fc4b6546fecbbbe8aa03fb7e73
https://doi.org/10.1158/1078-0432.22472232
https://doi.org/10.1158/1078-0432.22472232
Autor:
Alice L Yuan, Christian B Ricks, Alexandra K Bohm, Xueqing Lun, Lori Maxwell, Shahana Safdar, Shazreh Bukhari, Amanda Gerber, Wajid Sayeed, Elizabeth A Bering, Haley Pedersen, Jennifer A Chan, Yaoqing Shen, Marco Marra, David R Kaplan, Warren Mason, Lindsey D Goodman, Ravesanker Ezhilarasan, Ascher B Kaufmann, Matthew Cabral, Steve M Robbins, Donna L Senger, Daniel P Cahill, Erik P Sulman, J Gregory Cairncross, Michael D Blough
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202860 (2018)
BACKGROUND:Temozolomide (TMZ) is active against glioblastomas (GBM) in which the O6-methylguanine-DNA methyltransferase (MGMT) gene is silenced. However, even in responsive cases, its beneficial effect is undermined by the emergence of drug resistanc
Externí odkaz:
https://doaj.org/article/10de965f01cd437d8f49e05f6bc97413
Autor:
Derek S. Tsang, Mohammad M. Khandwala, Zhihui Amy Liu, Nadine Richard, Gerald Shen, Angela Sekely, Lori J. Bernstein, Rebecca Simpson, Warren Mason, Caroline Chung, Fabio Ynoe de Moraes, Louise Murray, David Shultz, Normand Laperriere, Barbara-Ann Millar, Kim Edelstein
Publikováno v:
Advances in radiation oncology. 7(6)
The contributory effects of radiation dose to different brain regions on neurocognitive performance after radiation therapy (RT) for primary brain tumors is not well known.In this retrospective cohort study, 30 patients with brain tumors treated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d747feaf5190590dd48b4764eee1148f
https://pubmed.ncbi.nlm.nih.gov/36420185
https://pubmed.ncbi.nlm.nih.gov/36420185
Autor:
Julie Bennett, Liana Nobre, Javal Sheth, Scott Ryall, Karen Fang, Monique Johnson, Logine Negm, Jiil Chung, Martin Komosa, Nuno Nunes, Mary Jane Lim-Fat, James Perry, Arjun Sahgal, Jay Detsky, Eric Bouffet, Lili-Naz Hazrati, Peter Dirks, Birgit Ertl-Wagner, Paul Kongkham, Gelareh Zadeh, Warren Mason, Michael Cusimano, Sunit Das, Andrew Gao, Derek Tsang, Lananh Nguyen, Normand Laperriere, Julia Keith, David Munoz, Uri Tabori, Cynthia Hawkins
Publikováno v:
Neuro-Oncology. 24:vii115-vii115
OBJECTIVE Gliomas in adolescents and young adults (AYA) are commonly treated with a standard chemo-radiation approach. Molecular alterations have not been comprehensively described to date. METHODS We compiled a multi-institutional cohort of patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::419367b2087145aab856aa33ff9d9c77
https://doi.org/10.1093/neuonc/noac209.435
https://doi.org/10.1093/neuonc/noac209.435
Autor:
Matthijs van der Meulen, Ronald Ramos, Mathew Voisin, Vikas Patil, Qingxia Wei, Olivia Singh, Seth Climans, Navya Kalidindi, Rosamarylin Or, Phideas Diamandis, David Munoz, Gelareh Zadeh, Warren Mason
Publikováno v:
Neuro-Oncology. 24:vii156-vii156
INTRODUCTION Patients with glioblastomas (GBM) have an overall survival (OS) of approximately 15 months. However, approximately 5% of patients survive much longer, with an OS of > 5 years. This study examines the differences in methylation profiles b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16cafcf8ae40e05089224b62a6ed13b0
https://doi.org/10.1093/neuonc/noac209.601
https://doi.org/10.1093/neuonc/noac209.601