Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Warren, AY"'
Autor:
Andreou, A, Yngvadottir, B, Bassaganyas, L, Clarke, G, Martin, E, Whitworth, J, Cornish, AJ, Genomics England Research Consortium, Houlston, RS, Rich, P, Egan, C, Hodgson, SV, Warren, AY, Snape, K, Maher, ER
BACKGROUND: Around 95% of patients with clinical features diagnostic of Von Hippel-Lindau disease (VHL) have a detectable inactivating germline variant in VHL. The VHL protein (pVHL) functions as part of the VCB-CR complex which plays a key role in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::36ca96e0634a875907d61c593142a2df
https://openaccess.sgul.ac.uk/id/eprint/114242/6/ddac066.pdf
https://openaccess.sgul.ac.uk/id/eprint/114242/6/ddac066.pdf
Autor:
Bryant, RJ, Oxley, J, Young, GJ, Lane, JA, Metcalfe, C, Davis, M, Turner, EL, Martin, RM, Goepel, JR, Varma, M, Griffiths, DF, Grigor, K, Mayer, N, Warren, AY, Bhattarai, S, Dormer, J, Mason, M, Staffurth, J, Walsh, E, Rosario, DJ, F Catto, JW, Neal, DE, Donovan, JL, Hamdy, FC, Protect Study Group, Bollina, P, Doble, A, Doherty, A, Gillatt, D, Gnanapragasam, V, Hughes, O, Kockelbergh, R, Kynaston, H, Paul, A, Paez, E, Rowe, E
Publikováno v:
Bryant, R J, Oxley, J, Young, G J, Lane, J A, Metcalfe, C, Davis, M, Turner, E L, Martin, R M, Goepel, J R, Varma, M, Griffiths, D F, Grigor, K, Mayer, N, Warren, A Y, Bhattarai, S, Dormer, J, Mason, M, Staffurth, J, Walsh, E, Rosario, D J, F Catto, J W, Neal, D E, Donovan, J L, Hamdy, F C, Bollina, P, Doble, A, Doherty, A, Gillatt, D, Gnanapragasam, V, Hughes, O, Kockelbergh, R, Kynaston, H, Paul, A, Paez, E, Rowe, E & the ProtecT Study Group 2020, ' The ProtecT trial : analysis of the patient cohort, baseline risk stratification and disease progression ', BJU International . https://doi.org/10.1111/bju.14987
OBJECTIVES: The ProtecT (Prostate testing for cancer and Treatment) trial randomised 1,643 men with localised prostate cancer (PCa) to active monitoring, radical prostatectomy or radical radiotherapy. At 10-year median follow-up there were no differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f116adeea8a4a0e19e6d297cd979bd54
https://doi.org/10.1111/bju.14987
https://doi.org/10.1111/bju.14987
Autor:
Abedi-Ardekani, B, Nasrollahzadeh, D, Egevad, L, Banks, RE, Vasudev, N, Holcatova, I, Povysil, C, Foretova, L, Janout, V, Mates, D, Jinga, V, Petrescu, A, Milosavljevic, S, Ognjanovic, M, Ognjanovic, S, Viksna, J, Warren, AY, Lathrop, M, Riazalhosseini, Y, Carreira, C, McKay, J, Brennan, P, Scélo, G
There are unexplained geographical variations in the incidence of kidney cancer with the high rates reported in Baltic countries, as well as eastern and central Europe. Having access to a large and well-annotated collection of “tumor/non-tumor” p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::307017b21a5a217f5acf8a3866dfe718
https://eprints.whiterose.ac.uk/168644/7/Abedi-Ardekani2021_Article_MorphologicalFindingsInFrozenN.pdf
https://eprints.whiterose.ac.uk/168644/7/Abedi-Ardekani2021_Article_MorphologicalFindingsInFrozenN.pdf
Autor:
Asim, M, Tarish, F, Zecchini, HI, Sanjiv, K, Gelali, E, Massie, CE, Baridi, A, Warren, AY, Zhao, W, Ogris, C, McDuffus, L-A, Mascalchi, P, Shaw, G, Dev, H, Wadhwa, K, Wijnhoven, P, Forment, JV, Lyons, SR, Lynch, AG, O'Neill, C, Zecchini, VR, Rennie, PS, Baniahmad, A, Tavaré, S, Mills, IG, Galanty, Y, Crosetto, N, Schultz, N, Neal, D, Helleday, T
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Asim, M, Tarish, F, Ireland-Zecchini, H, Sanjiv, K, Gelali, E, Massie, C E, Baridi, A, Warren, A Y, Zhao, W, Ogris, C, McDuffus, L-A, Mascalchi, P, Shaw, G L, Dev, H, Wadhwa, K, Wijnhoven, P, Forment, J V, Lyons, S R, Lynch, A G, O'Neill, C, Zecchini, V R, Rennie, P S, Baniahmad, A, Tavaré, S, Mills, I G, Galanty, Y, Crosetto, N, Schultz, N, Neal, D E & Helleday, T 2017, ' Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer ', Nature Communications, vol. 8, no. 1, pp. 374 . https://doi.org/10.1038/s41467-017-00393-y
Nature Communications
Asim, M, Tarish, F, Ireland-Zecchini, H, Sanjiv, K, Gelali, E, Massie, C E, Baridi, A, Warren, A Y, Zhao, W, Ogris, C, McDuffus, L-A, Mascalchi, P, Shaw, G L, Dev, H, Wadhwa, K, Wijnhoven, P, Forment, J V, Lyons, S R, Lynch, A G, O'Neill, C, Zecchini, V R, Rennie, P S, Baniahmad, A, Tavaré, S, Mills, I G, Galanty, Y, Crosetto, N, Schultz, N, Neal, D E & Helleday, T 2017, ' Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer ', Nature Communications, vol. 8, no. 1, pp. 374 . https://doi.org/10.1038/s41467-017-00393-y
Emerging data demonstrate homologous recombination (HR) defects in castration-resistant prostate cancers, rendering these tumours sensitive to PARP inhibition. Here we demonstrate a direct requirement for the androgen receptor (AR) to maintain HR gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c2bd153c3c2b27cda275d2deb5d68ea4
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Sharma, NL, Papadopoulos, A, Lee, D, McLoughlin, J, Vowler, SL, Baumert, H, Warren, AY, Patil, V, Shah, N, Neal, DE
OBJECTIVE: • To study the outcomes and learning curve of robotic-assisted laparoscopic radical prostatectomy (RALP) in a single centre by two surgeons. PATIENTS AND METHODS: • In total, 500 consecutive patients underwent RALP between 2005 and 200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5ec1b055f1299e7955d25577c08fcada
https://doi.org/10.1111/j.1464-410x.2010.09941.x
https://doi.org/10.1111/j.1464-410x.2010.09941.x
Autor:
Ross-Adams, H, Lamb, AD, Dunning, MJ, Halim, S, Lindberg, J, Massie, CM, Egevad, LA, Russell, R, Ramos-Montoya, A, Vowler, SL, Sharma, NL, Kay, J, Whitaker, H, Clark, J, Hurst, R, Gnanapragasam, VJ, Shah, NC, Warren, AY, Cooper, CS, Lynch, AG, Stark, R, Mills, IG, Grönberg, H, Neal, DE, CamCaP Study Group
BACKGROUND: Understanding the heterogeneous genotypes and phenotypes of prostate cancer is fundamental to improving the way we treat this disease. As yet, there are no validated descriptions of prostate cancer subgroups derived from integrated genomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::795ed299d114857653fbcaaf84533955
https://www.repository.cam.ac.uk/handle/1810/249005
https://www.repository.cam.ac.uk/handle/1810/249005
Autor:
Shaw, GL, Thomas, BC, Dawson, SN, Srivastava, G, Vowler, SL, Gnanapragasam, VJ, Shah, NC, Warren, AY, Neal, DE
BACKGROUND: Identification of men harbouring insignificant prostate cancer (PC) is important in selecting patients for active surveillance. Tools have been developed in PSA-screened populations to identify such men based on clinical and biopsy parame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b328516dfd4808485bc94434595c10db
https://www.repository.cam.ac.uk/handle/1810/276853
https://www.repository.cam.ac.uk/handle/1810/276853
Publikováno v:
Annals of the Royal College of Surgeons of England; 2018, Vol. 100 Issue 3, p226-229, 4p
Autor:
Whitaker, HC, Kote-Jarai, Z, Ross-Adams, H, Warren, AY, Burge, J, George, A, Bancroft, E, Jhavar, S, Leongamornlert, D, Tymrakiewicz, M, Saunders, E, Page, E, Mitra, A, Mitchell, G, Lindeman, GJ, Evans, DG, Blanco, I, Mercer, C, Rubinstein, WS, Clowes, V, Douglas, F, Hodgson, S, Walker, L, Donaldson, A, Izatt, L, Dorkins, H, Male, A, Tucker, K, Stapleton, A, Lam, J, Kirk, J, Lilja, H, Easton, D, IMPACT Study Steering Committee, IMPACT Study Collaborators, UK GPCS Collaborators, Cooper, C, Eeles, R, Neal, DE
Publikováno v:
PLoS ONE
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS ONE, Vol 5, Iss 10, p e13363 (2010)
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS ONE, Vol 5, Iss 10, p e13363 (2010)
Dipòsit Digital de la UB
Universidad de Barcelona
BACKGROUND: Microseminoprotein-beta (MSMB) regulates apoptosis and using genome-wide association studies the rs10993994 single nucleotide polymorphism in the MSMB promoter has been linked to an increased risk of developing prostate cancer. The promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36bec495219fc81d5347ea33a2c65d0
http://ora.ox.ac.uk/objects/uuid:ba9cdf50-8d91-4afb-82f6-d0981c621127
http://ora.ox.ac.uk/objects/uuid:ba9cdf50-8d91-4afb-82f6-d0981c621127
Autor:
Cooper, CS, Eeles, R, Wedge, DC, Van Loo, P, Gundem, G, Alexandrov, LB, Kremeyer, B, Butler, A, Lynch, AG, Camacho, N, Massie, CE, Kay, J, Luxton, HJ, Edwards, S, Kote-Jarai, Z, Dennis, N, Merson, S, Leongamornlert, D, Zamora, J, Corbishley, C, Thomas, S, Nik-Zainal, S, Ramakrishna, M, O'Meara, S, Matthews, L, Clark, J, Hurst, R, Mithen, R, Bristow, RG, Boutros, PC, Fraser, M, Cooke, S, Raine, K, Jones, D, Menzies, A, Stebbings, L, Hinton, J, Teague, J, McLaren, S, Mudie, L, Hardy, C, Anderson, E, Joseph, O, Goody, V, Robinson, B, Maddison, M, Gamble, S, Greenman, C, Berney, D, Hazell, S, Livni, N, ICGC Prostate Group, Fisher, C, Ogden, C, Kumar, P, Thompson, A, Woodhouse, C, Nicol, D, Mayer, E, Dudderidge, T, Shah, NC, Gnanapragasam, V, Voet, T, Campbell, P, Futreal, A, Easton, D, Warren, AY, Foster, CS, Stratton, MR, Whitaker, HC, McDermott, U, Brewer, DS, Neal, DE
Publikováno v:
Nature Genetics. 47:689-689
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce40661f01f29c1de9f4b5fddc47c16d
https://doi.org/10.1038/ng0615-689b
https://doi.org/10.1038/ng0615-689b