Human ITGAV variants are associated with immune dysregulation, brain abnormalities, and colitis.

Autor: Ghasempour S; Cell Biology Program, Research Institute, Hospital for Sick Children , Toronto, Canada.; Department of Biochemistry, University of Toronto, Toronto, Canada., Warner N; Cell Biology Program, Research Institute, Hospital for Sick Children , Toronto, Canada., Guan R; Cell Biology Program, Research Institute, Hospital for Sick Children , Toronto, Canada., Rodari MM; Laboratory of Intestinal Immunity, Université Paris-Cité, Institut Imagine, INSERM U1163 , Paris, France., Ivanochko D; Program in Molecular Medicine, The Hospital for Sick Children Research Institute , Toronto, Canada., Whittaker Hawkins R; Cell Biology Program, Research Institute, Hospital for Sick Children , Toronto, Canada., Marwaha A; Division of Genetics, Department of Medical Genetics, University of Calgary, Alberta Children's Hospital, Calgary, Canada., Nowak JK; Laboratory of Intestinal Immunity, Université Paris-Cité, Institut Imagine, INSERM U1163 , Paris, France., Liang Y; Center for Computational Medicine, Research Institute, Hospital for Sick Children , Toronto, Canada., Mulder DJ; Department of Pediatrics, Gastrointestinal Diseases Research Unit, Queen's University, Kingston, Canada., Stallard L; National Centre for Pediatric Gastroenterology, Children's Health Ireland , Dublin, Ireland., Li M; Center for Computational Medicine, Research Institute, Hospital for Sick Children , Toronto, Canada., Yu DD; Cell Biology Program, Research Institute, Hospital for Sick Children , Toronto, Canada., Pluthero FG; Department of Biochemistry, University of Toronto, Toronto, Canada., Batura V; Cell Biology Program, Research Institute, Hospital for Sick Children , Toronto, Canada., Zhao M; Genetics and Genome Biology, Research Institute, Hospital for Sick Children , Toronto, Canada., Siddiqui I; Division of Pathology, Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Canada.; Laboratory Medicine and Pathobiology, University of Toronto , Toronto, Canada., Upton JEM; Division of Immunology and Allergy, The Hospital for Sick Children, Toronto, Canada.; Department of Paediatrics, University of Toronto, Toronto, Canada., Hulst JM; Department of Paediatrics, University of Toronto, Toronto, Canada.; Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Canada., Kahr WHA; Cell Biology Program, Research Institute, Hospital for Sick Children , Toronto, Canada.; Department of Biochemistry, University of Toronto, Toronto, Canada.; Department of Paediatrics, University of Toronto, Toronto, Canada., Mendoza-Londono R; Department of Paediatrics, University of Toronto, Toronto, Canada.; Division of Clinical and Metabolic Genetics, Department of Paediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Canada., Charbit-Henrion F; Laboratory of Intestinal Immunity, Université Paris-Cité, Institut Imagine, INSERM U1163 , Paris, France.; Genomic Medicine for Rare Diseases, Necker-Enfants Malades Hospital , Paris, France., Hoefsloot LH; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands., Khiat A; Laboratory of Intestinal Immunity, Université Paris-Cité, Institut Imagine, INSERM U1163 , Paris, France., Moreira D; Consulta de Imunodeficiências Primárias, Serviço de Pediatria, Centro Hospitalar Vila Nova de Gaia e Espinho , Vila Nova de Gaia, Portugal., Trindade E; Department of Pediatrics, Unit of Pediatric Gastroenterology, Hepatology and Nutrition, Centro Hospitalar Universitário de São João, Porto, Portugal., Espinheira MDC; Department of Pediatrics, Unit of Pediatric Gastroenterology, Hepatology and Nutrition, Centro Hospitalar Universitário de São João, Porto, Portugal., Pinto Pais I; Department of Pediatrics, Unit of Pediatric Gastroenterology, Hepatology and Nutrition, Centro Hospitalar Universitário de São João, Porto, Portugal., Weerts MJA; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands., Douben H; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands., Kotlarz D; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Munich, Germany.; German Center for Child and Adolescent Health, Munich Site , Munich, Germany.; Institute of Translational Genomics, Helmholtz Zentrum München German Research Center for Environmental Health, Neuherberg, Germany., Snapper SB; Division of Gastroenterology, Hepatology and Nutrition, Boston, Children's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA, USA., Klein C; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Munich, Germany.; German Center for Child and Adolescent Health, Munich Site , Munich, Germany., Dowling JJ; Genetics and Genome Biology, Research Institute, Hospital for Sick Children , Toronto, Canada.; Department of Paediatrics, University of Toronto, Toronto, Canada., Julien JP; Program in Molecular Medicine, The Hospital for Sick Children Research Institute , Toronto, Canada., Joosten M; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands., Cerf-Bensussan N; Laboratory of Intestinal Immunity, Université Paris-Cité, Institut Imagine, INSERM U1163 , Paris, France., Freeman SA; Cell Biology Program, Research Institute, Hospital for Sick Children , Toronto, Canada.; Department of Biochemistry, University of Toronto, Toronto, Canada., Parlato M; Laboratory of Intestinal Immunity, Université Paris-Cité, Institut Imagine, INSERM U1163 , Paris, France., van Ham TJ; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands., Muise AM; Cell Biology Program, Research Institute, Hospital for Sick Children , Toronto, Canada.; Department of Biochemistry, University of Toronto, Toronto, Canada.; Department of Paediatrics, University of Toronto, Toronto, Canada.; Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Canada.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2024 Dec 02; Vol. 221 (12). Date of Electronic Publication: 2024 Nov 11.

Tachyon Condensation on the Elliptic Curve

Autor: Govindarajan, S., Jockers, H., Lerche, W., Warner, N.

Publikováno v: Nucl.Phys.B765:240-286,2007

We use the framework of matrix factorizations to study topological B-type D-branes on the cubic curve. Specifically, we elucidate how the brane RR charges are encoded in the matrix factors, by analyzing their structure in terms of sections of vector

Externí odkaz: http://arxiv.org/abs/hep-th/0512208

A Dielectric Flow Solution with Maximal Supersymmetry

Autor: Pope, C. N., Warner, N. P.

Publikováno v: JHEP 0404:011,2004

We obtain a solution to eleven-dimensional supergravity that consists of M2-branes embedded in a dielectric distribution of M5-branes. Contrary to normal expectations, this solution has maximal supersymmetry for a brane solution (i.e. sixteen superch

Externí odkaz: http://arxiv.org/abs/hep-th/0304132

Holomorphic N=1 Special Geometry of Open--Closed Type II Strings

Autor: Lerche, W., Mayr, P., Warner, N.

We outline a general geometric structure that underlies the N=1 superpotentials of a certain class of flux and brane configurations in type II string compactifications on Calabi-Yau threefolds. This ``holomorphic N=1 special geometry'' is in many res

Externí odkaz: http://arxiv.org/abs/hep-th/0207259

Continuous distributions of D3-branes and gauged supergravity

Autor: Freedman, D. Z., Gubser, S. S., Pilch, K., Warner, N. P.

Publikováno v: JHEP 0007:038,2000

States on the Coulomb branch of N=4 super-Yang-Mills theory are studied from the point of view of gauged supergravity in five dimensions. These supersymmetric solutions provide examples of consistent truncation from type IIB supergravity in ten dimen

Externí odkaz: http://arxiv.org/abs/hep-th/9906194