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Akademický článek

It's Ok To Coddiwomple: Anthropology, Peacebuilding and (Em)Bracing the Vague

Autor: Warner Charles O.

Publikováno v: SEEU Review, Vol 19, Iss 1, Pp 3-23 (2024)

This white paper takes the unknown and the vague and movement towards/in those realms – as frames for a discussion of present practice and emergent potentiality of anthropological engagement with peace (building) studies. Arguably, embracing the un

Externí odkaz: https://doaj.org/article/04ffe98406e64d62904752504e03c79c

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Akademický článek

Correlation of changes in inflammatory and collagen biomarkers with durable guselkumab efficacy through 2 years in participants with active psoriatic arthritis: results from a phase III randomized controlled trial

Autor: Stefan Siebert, Georg Schett, Siba P. Raychaudhuri, Monica Guma, Warner Chen, Sheng Gao, Soumya D. Chakravarty, Frederic Lavie, Proton Rahman

Publikováno v: Therapeutic Advances in Musculoskeletal Disease, Vol 16 (2024)

Background: Guselkumab (human monoclonal antibody) selectively inhibits the interleukin (IL)-23p19 subunit. Objectives: Assess the longer-term pharmacodynamic effects of guselkumab and explore associations between such effects and clinical responses

Externí odkaz: https://doaj.org/article/5fabba911e814e3b861bb0ca24ddd72f

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Akademický článek

Guselkumab Modulates Differentially Expressed Genes in Blood of Patients With Psoriatic Arthritis: Results from Two Phase 3, Randomized, Placebo‐Controlled Trials

Autor: Stefan Siebert, Kristen M. Sweet, Christopher T. Ritchlin, Elizabeth C. Hsia, Alexa P. Kollmeier, Xie L. Xu, Loqmane Seridi, Qingxuan Song, Sheng Gao, Warner Chen, Michelle Miron

Publikováno v: ACR Open Rheumatology, Vol 5, Iss 9, Pp 490-498 (2023)

Objective To evaluate gene expression in blood of patients with psoriatic arthritis (PsA) versus healthy controls and identify changes associated with guselkumab treatment. Methods Whole blood transcriptome profiling via paired‐end RNA sequencing w

Externí odkaz: https://doaj.org/article/ee686f1b1c8d4522be8be3992db06eb5

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Akademický článek

Effect of guselkumab on serum biomarkers in patients with active psoriatic arthritis and inadequate response to tumor necrosis factor inhibitors: results from the COSMOS phase 3b study

Autor: Georg Schett, Warner Chen, Sheng Gao, Soumya D. Chakravarty, May Shawi, Frederic Lavie, Miriam Zimmermann, Mohamed Sharaf, Laura C. Coates, Stefan Siebert

Publikováno v: Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-11 (2023)

Abstract Background Guselkumab is a selective interleukin (IL)-23 inhibitor targeting the IL-23p19 subunit. In the phase 3b COSMOS trial, guselkumab demonstrated efficacy in treating participants with active psoriatic arthritis (PsA) and inadequate r

Externí odkaz: https://doaj.org/article/dcfb8eb123704ee0a98a378fd8f4608d

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