Zobrazeno 1 - 10
of 401
pro vyhledávání: '"Warmflash, A."'
Autor:
Camacho-Aguilar, Elena, Yoon, Sumin T., Ortiz-Salazar, Miguel A., Du, Siqi, Guerra, M. Cecilia, Warmflash, Aryeh
Publikováno v:
In Cell Systems 15 May 2024 15(5):445-461
In this paper we consider mathematical modeling of the dynamics of self-organized patterning of spatially confined human embryonic stem cells (hESCs) treated with BMP4 (gastruloids) described in recent experimental works. In the first part of the pap
Externí odkaz:
http://arxiv.org/abs/2101.03474
Akademický článek
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Autor:
Emily Sempou, Valentyna Kostiuk, Jie Zhu, M. Cecilia Guerra, Leonid Tyan, Woong Hwang, Elena Camacho-Aguilar, Michael J. Caplan, David Zenisek, Aryeh Warmflash, Nick D. L. Owens, Mustafa K. Khokha
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Transitioning from pluripotency to differentiated cell fates is fundamental to both embryonic development and adult tissue homeostasis. Improving our understanding of this transition would facilitate our ability to manipulate pluripotent cel
Externí odkaz:
https://doaj.org/article/58862aeb53a640a4ba563a0187c09257
Autor:
Siggia, Eric D., Warmflash, Aryeh
Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the physical an
Externí odkaz:
http://arxiv.org/abs/1712.03335
Autor:
Lizhong Liu, Anastasiia Nemashkalo, Luisa Rezende, Ji Yoon Jung, Sapna Chhabra, M. Cecilia Guerra, Idse Heemskerk, Aryeh Warmflash
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Studying morphogen gradient formation and reception in mammalian development is challenging. Here, the authors show with human gastruloids that Nodal activity in live cells spreads via a relay mechanism with timing that is locally controlled by Lefty
Externí odkaz:
https://doaj.org/article/761cef3c609c49fe980780566f2cc4d2
Autor:
Emily Sempou, Valentyna Kostiuk, Jie Zhu, M. Cecilia Guerra, Leonid Tyan, Woong Hwang, Elena Camacho-Aguilar, Michael J. Caplan, David Zenisek, Aryeh Warmflash, Nick D. L. Owens, Mustafa K. Khokha
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/32a4bc62762c4d869617691f1d6c7801
Autor:
Arun S Mahadevan, Byron L Long, Chenyue W Hu, David T Ryan, Nicolas E Grandel, George L Britton, Marisol Bustos, Maria A Gonzalez Porras, Katerina Stojkova, Andrew Ligeralde, Hyeonwi Son, John Shannonhouse, Jacob T Robinson, Aryeh Warmflash, Eric M Brey, Yu Shin Kim, Amina A Qutub
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 6, p e1009846 (2022)
We introduce cytoNet, a cloud-based tool to characterize cell populations from microscopy images. cytoNet quantifies spatial topology and functional relationships in cell communities using principles of network science. Capturing multicellular dynami
Externí odkaz:
https://doaj.org/article/68be8c3e4b864f43830fbc95545cafd3
Autor:
Massey, Joseph, Liu, Yida, Alvarenga, Omar, Saez, Teresa, Schmerer, Matthew, Warmflash, Aryeh
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Mar 01. 116(11), 4989-4998.
Externí odkaz:
https://www.jstor.org/stable/26672197
Autor:
Sapna Chhabra, Aryeh Warmflash
Publikováno v:
Biology Open, Vol 10, Iss 9 (2021)
Human embryonic stem cells (hESCs) possess an immense potential to generate clinically relevant cell types and unveil mechanisms underlying early human development. However, using hESCs for discovery or translation requires accurately identifying dif
Externí odkaz:
https://doaj.org/article/ea2d9a68b850493db62054d63e60eaaf