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Akademický článek

Carbachol Potentiates Cholera Toxin-induced Secretion in a Colonic Epithelial Cell Line (HT29-19A) and Rat Ileal Mucosa In Vitro

Autor: Mahmood, B., Warhurst, G., Higgs, N., Turnberg, L.A.

Publikováno v: Journal of Health, Population and Nutrition, 2000 Jun 01. 18(1), 49-53.

Externí odkaz: https://www.jstor.org/stable/23499064

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Stability in metabolic phenotypes and inferred metagenome profiles before the onset of colitis-induced inflammation

Autor: Glymenaki, M, Barnes, A, Hagan, S O', Warhurst, G, McBain, AJ, Wilson, ID, Kell, DB, Else, KJ, Cruickshank, SM

Publikováno v: Glymenaki, M, Barnes, A, O'Hagan, S, Warhurst, G, Mcbain, A, Wilson, I D, Kell, D, Else, K & Cruickshank, S 2017, ' Stability in metabolic phenotypes and inferred metagenome profiles before the onset of colitis-induced inflammation ', Scientific Reports, vol. 7 . https://doi.org/10.1038/s41598-017-08732-1
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
SCIENTIFIC REPORTS

Inflammatory bowel disease (IBD) is associated with altered microbiota composition and metabolism, but it is unclear whether these changes precede inflammation or are the result of it since current studies have mainly focused on changes after the ons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dac6b735959ecd5981be06867c03f18f
https://doi.org/10.1038/s41598-017-08732-1

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Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro–in vivo extrapolation of oral drug absorption

Autor: Harwood, MD, Neuhoff, S., Carlson, G.L., Warhurst, G., Rostami-Hodjegan, Amin

Publikováno v: Harwood, MD, Neuhoff, S, Carlson, G L, Warhurst, G & Rostami-Hodjegan, A 2013, ' Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro–in vivo extrapolation of oral drug absorption ', Biopharm Drug Dispos, vol. 34, no. 1, pp. 2-28 . https://doi.org/10.1002/bdd.1810, https://doi.org/10.1002/bdd.1810

The use of whole body physiological-based pharmacokinetic (PBPK) models linked with in vitro-in vivo extrapolation (IVIVE) of kinetic parameters from laboratory experiments, has become embedded within many of the pharmaceutical industry and is used e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9a35f9d47fb6ce1bfc30cfcde3b43506
https://www.research.manchester.ac.uk/portal/en/publications/absolute-abundance-and-function-of-intestinal-drug-transporters-a-prerequisite-for-fully-mechanistic-in-vitroin-vivo-extrapolation-of-oral-drug-absorption(0c104604-3ce1-49b1-b704-59f8e1162e82).html

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Inflammatory bowel disease and trichuris muris

Autor: Bhardwaj, E, Else, K, Warhurst, G, Rogan, MT

Publikováno v: Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is a group of idiopathic chronic relapsing inflammatory\ud conditions of the gastrointestinal tract. The precise etiology of IBD is unknown,\ud although it is clearly multifactorial resulting from interplay of genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::0e43ab7ba00afe9dadb1db7e26d349eb
https://usir.salford.ac.uk/id/eprint/19243/1/Bhardwaj_2008.pdf

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Akademický článek

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Anti-secretory properties of non-peptide somatostatin receptor agonists in isolated rat colon: luminal activity and possible interaction with p-glycoprotein

Autor: Emery, P T J, Higgs, N B, Warhurst, A C, Carlson, G L, Warhurst, G

1. The diverse physiological actions of somatostatin are mediated by a family of G-protein coupled receptors (SSTRs). Several peptide analogues of somatostatin such as octreotide have been developed for therapeutic use, including treatment of gastroi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f55a0b191cef4dca407a090e1b41d041
https://europepmc.org/articles/PMC1573276/

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Akademický článek

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