Zobrazeno 1 - 10
of 386
pro vyhledávání: '"Warhurst DC"'
Publikováno v:
Lancet. 11/16/2002, Vol. 360 Issue 9345, p1527-1529. 3p.
Autor:
Menegon, M, Pearce, Rj, Inojosa, Wo, Pisani, V, Abel, Pm, Matondo, A, Bisoffi, Z, Majori, G, Ord, R, Warhurst, Dc, Roper, C, Severini, C
Publikováno v:
Tropical medicineinternational health : TMIH. 14(10)
To assess the extent of drug resistance in Uige through molecular genetic analysis and to test whether the dhfr triple mutant alleles present in Angola are of southeast Asian origin.Seventy-one samples of blood from children admitted to the Pediatric
Publikováno v:
Acta Médica Portuguesa; v. 16, n. 4 (2003): Julho-Agosto; 229-33
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Isolates of Plasmodium falciparum from three areas of West Africa were recovered from cryopreservation and their chloroquine-sensitivity were determined in vitro. Of the 90 samples studied, 60 were from Guinea-Bissau (30Resistant/30Sensitive), 15 wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::81d7fe6bebaca4cd284c3d983b866e46
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1191
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1191
A multiplex allele specific polymerase chain reaction (MAS-PCR) based on the Cryptosporidium parvum dihydrofolate reductase (dhfr) gene sequence differentiates genotype 1 ('Human') from 2 ('Cattle') in a 1-step reaction. The MAS-PCR was validated on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::aaa5a9775c2ce1d106e1c0b904e18fd8
https://researchonline.lshtm.ac.uk/id/eprint/15747/1/Multiplex.pdf
https://researchonline.lshtm.ac.uk/id/eprint/15747/1/Multiplex.pdf
Autor:
Adagu, IS, Warhurst, DC
In view of the recent discovery (Molecular Cell 6, 861-871) of a (Lys76Thr) codon change in gene pfcrt on chromosome 7 which determines in vitro chloroquine resistance in Plasmodium falciparum, we have re-examined samples taken before treatment in ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::9f97a409aed966df1bf9537669e0e9e2
https://researchonline.lshtm.ac.uk/id/eprint/16302/1/Plasmo.pdf
https://researchonline.lshtm.ac.uk/id/eprint/16302/1/Plasmo.pdf
Autor:
Williams, JE, Warhurst, DC
Publikováno v:
Practical Exercises in Parasitology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::f3b97a358e20bb27e3123d490a7b6399
Lumefantrine binds to hemin produced during hemoglobin breakdown, preventing detoxification to crystalline malaria pigment (hemozoin). During the same process, the perOXide group in artemether binds to heme and releases toxic free-radicals. Resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::54d5f894952d1208d63fee25f4a08c45
https://researchonline.lshtm.ac.uk/id/eprint/1904/1/WarhurstSEAsianJ2001cartagena2000consensus2001_2.pdf
https://researchonline.lshtm.ac.uk/id/eprint/1904/1/WarhurstSEAsianJ2001cartagena2000consensus2001_2.pdf
Publikováno v:
Parasitology, 116(3), 211-217. Cambridge University Press
Plasmodium falciparum resistance to chloroquine has been described in many parts of the world particularly in Africa where malaria is endemic. High levels of chloroquine resistance in our study area, Lambarene-Gabon, has led to the use of an alternat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fea51d24048583378282e0caeeb3bd
https://pure.amc.nl/en/publications/plasmodium-falciparum-in-vitro-chloroquine-susceptibility-and-allelespecific-pcr-detection-of-pfmdr1-asn86tyr-polymorphism-in-lambarene-gabon(abfae1eb-1f3f-4414-ad18-33975f3af6e3).html
https://pure.amc.nl/en/publications/plasmodium-falciparum-in-vitro-chloroquine-susceptibility-and-allelespecific-pcr-detection-of-pfmdr1-asn86tyr-polymorphism-in-lambarene-gabon(abfae1eb-1f3f-4414-ad18-33975f3af6e3).html
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