Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Wardit Tigchelaar"'
Autor:
Hongjuan Yu, Wardit Tigchelaar, Debby P Y Koonen, Hemal H Patel, Rudolf A de Boer, Wiek H van Gilst, B Daan Westenbrink, Herman H W Silljé
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80815 (2013)
A kinase interacting protein 1 (AKIP1) is a molecular regulator of protein kinase A and nuclear factor kappa B signalling. Recent evidence suggests AKIP1 is increased in response to cardiac stress, modulates acute ischemic stress response, and is loc
Externí odkaz:
https://doaj.org/article/cfffa75d86364e4ab452dcc487d0ef62
Autor:
Wardit Tigchelaar, Wiek H. van Gilst, Rudolf A. de Boer, Anne Margreet De Jong, Herman H W Silljé
Publikováno v:
BioEssays. 38:S136-S145
Depletion of mitochondrial endo/exonuclease G-like (EXOG) in cultured neonatal cardiomyocytes stimulates mitochondrial oxygen consumption rate (OCR) and induces hypertrophy via reactive oxygen species (ROS). Here, we show that neurohormonal stress tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b418e5bde26f6b4921dfbe0a9093f6b5
https://doi.org/10.1002/bies.201670914
https://doi.org/10.1002/bies.201670914
Autor:
Hongjuan Yu, Rudolf A. de Boer, Anne Margreet De Jong, Wardit Tigchelaar, Herman H W Silljé, Pim van der Harst, B. Daan Westenbrink, Wiek H. van Gilst
Publikováno v:
American journal of physiology-Cell physiology, 308(2), C155-C163. AMER PHYSIOLOGICAL SOC
Recently, a locus at the mitochondrial exo/endonuclease EXOG gene, which has been implicated in mitochondrial DNA repair, was associated with cardiac function. The function of EXOG in cardiomyocytes is still elusive. Here we investigated the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f85fad13937e4d4fd874390a5726cc
https://doi.org/10.1152/ajpcell.00227.2014
https://doi.org/10.1152/ajpcell.00227.2014
Autor:
Wiek H. van Gilst, Hongjuan Yu, Bo Lu, B. Daan Westenbrink, Rudolf A. de Boer, Herman H W Silljé, Wardit Tigchelaar
Publikováno v:
International Journal of Molecular Sciences; Volume 14; Issue 11; Pages: 21378-21393
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 14(11), 21378-21393. MDPI AG
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 14(11), 21378-21393. MDPI AG
Cardiac adaptation to unremitting physiological stress typically involves hypertrophic growth of cardiomyocytes, a compensatory response that often fails and causes heart disease. Gene array analysis identified AKIP1 (A Kinase Interacting Protein 1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0581768bd12b003b875bb302b78c0c2c
https://doi.org/10.3390/ijms141121378
https://doi.org/10.3390/ijms141121378
Autor:
Wardit, Tigchelaar, Anne Margreet, De Jong, Wiek H, van Gilst, Rudolf A, De Boer, Herman H W, Silljé
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 38
Depletion of mitochondrial endo/exonuclease G-like (EXOG) in cultured neonatal cardiomyocytes stimulates mitochondrial oxygen consumption rate (OCR) and induces hypertrophy via reactive oxygen species (ROS). Here, we show that neurohormonal stress tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f645e1dfcf75b72f86d0ecf5272dbcd3
https://pubmed.ncbi.nlm.nih.gov/27417117
https://pubmed.ncbi.nlm.nih.gov/27417117
Autor:
Willem P. T. Ruifrok, Wiek H. van Gilst, Wardit Tigchelaar, Bo Lu, Rudolf A. de Boer, Herman H W Silljé
Publikováno v:
European Journal of Heart Failure, 14(1), 5-13. Wiley
Aims Although cardiac diseases account for the highest mortality and morbidity rates in Western society, there is still a considerable gap in our knowledge of genes that contribute to cardiac (dys) function. Here we screened for gene expression profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645eb236a9a29a22151d2ea5b1f635cf
https://pubmed.ncbi.nlm.nih.gov/22143674
https://pubmed.ncbi.nlm.nih.gov/22143674
Publikováno v:
Cardiovascular Research. 103:S78.4-S79
Purpose: The heart is one of the most energy consuming organs. This energy is used to maintain proper contractile function and is produced mainly in the mitochondria by oxidative phosphorylation (OXPHOS). The production of reactive oxygen species (RO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5244c37cf6b69d674111192188ca4276
https://doi.org/10.1093/cvr/cvu091.107
https://doi.org/10.1093/cvr/cvu091.107
Autor:
Wiek H. van Gilst, Debby P.Y. Koonen, Wardit Tigchelaar, Herman H W Silljé, Rudolf A. de Boer, B. Daan Westenbrink, Hemal H. Patel, Hongjuan Yu
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80815 (2013)
PLoS ONE, 8(11):e80815. PUBLIC LIBRARY SCIENCE
PLoS ONE
PLoS ONE, 8(11):e80815. PUBLIC LIBRARY SCIENCE
PLoS ONE
A kinase interacting protein 1 (AKIP1) is a molecular regulator of protein kinase A and nuclear factor kappa B signalling. Recent evidence suggests AKIP1 is increased in response to cardiac stress, modulates acute ischemic stress response, and is loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d31f660d1c277052f61219be5bedf8
https://doi.org/10.1371/journal.pone.0080815
https://doi.org/10.1371/journal.pone.0080815
Autor:
Rudolf A. de Boer, Wiek H. van Gilst, Anne Margreet De Jong, Herman H W Silljé, Wardit Tigchelaar, Vincent W. Bloks
Publikováno v:
Journal of molecular and cellular cardiology, 97, 70-81. ELSEVIER SCI LTD
Cardiac hypertrophy is associated with growth and functional changes of cardiomyocytes, including mitochondrial alterations, but the latter are still poorly understood. Here we investigated mitochondrial function and dynamic localization in neonatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58872ea0982c20bbc9698dabe651261c