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Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells.

Autor: Safi R; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Wardell SE; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Watkinson P; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Qin X; Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA., Lee M; Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA., Park S; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Krebs T; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Dolan EL; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Blattler A; Oncogenesis Thematic Research Center, Bristol Myers Squibb, San Diego, CA, USA., Tsuji T; Oncogenesis Thematic Research Center, Bristol Myers Squibb, San Diego, CA, USA., Nayak S; Oncogenesis Thematic Research Center, Bristol Myers Squibb, San Diego, CA, USA., Khater M; Informatics and Predictive Sciences, Bristol Myers Squibb, San Diego, CA, USA., Fontanillo C; Informatics and Predictive Sciences, Bristol Myers Squibb, San Diego, CA, USA., Newlin MA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Kirkland ML; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., Xie Y; Dana-Farber Cancer Institute, Boston, MA, USA., Long H; Dana-Farber Cancer Institute, Boston, MA, USA., Fink EC; Department of Cancer Biology, Loyola University, Maywood, IL, USA., Fanning SW; Department of Cancer Biology, Loyola University, Maywood, IL, USA., Runyon S; RTI International, Research Triangle Park, NC, USA., Brown M; Dana-Farber Cancer Institute, Boston, MA, USA., Xu S; Oncogenesis Thematic Research Center, Bristol Myers Squibb, San Diego, CA, USA., Owzar K; Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA., Norris JD; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA., McDonnell DP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA. Donald.McDonnell@duke.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Sep 03; Vol. 15 (1), pp. 7675. Date of Electronic Publication: 2024 Sep 03.

Development and Characterization of a Luciferase Labeled, Syngeneic Murine Model of Ovarian Cancer.

Autor: Russell S; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA., Lim F; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA., Peters PN; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Duke University School of Medicine, Durham, NC 27710, USA., Wardell SE; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA., Whitaker R; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Duke University School of Medicine, Durham, NC 27710, USA., Chang CY; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA., Previs RA; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Duke University School of Medicine, Durham, NC 27710, USA., McDonnell DP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA.

Publikováno v: Cancers [Cancers (Basel)] 2022 Aug 30; Vol. 14 (17). Date of Electronic Publication: 2022 Aug 30.

Inhibition of estrogen signaling in myeloid cells increases tumor immunity in melanoma.

Autor: Chakraborty B; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Byemerwa J; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Shepherd J; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Haines CN; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Baldi R; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Gong W; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Liu W; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Mukherjee D; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Artham S; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Lim F; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Bae Y; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Brueckner O; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Tavares K; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Wardell SE; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Hanks BA; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA., Perou CM; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Chang CY; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., McDonnell DP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2021 Dec 01; Vol. 131 (23).