Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ward R. Richter"'
Publikováno v:
Toxicology. 128:135-141
Tri-n-butyl phosphate (TBP), an industrial chemical, was administered in the diet at concentrations of 0, 150, 1000 or 3500 ppm to groups of 50 male and 50 female CD-1 mice for 18 months. Survival, clinical signs and hematology parameters were unaffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33929d1606130d711341a892c636b404
https://doi.org/10.1016/s0300-483x(98)00056-0
https://doi.org/10.1016/s0300-483x(98)00056-0
Publikováno v:
Toxicology. 128:125-134
Tri-n-butyl phosphate (TBP, CAS No. 126-73-8), an industrial chemical, was administered in the diet at concentrations of 0, 200, 700 and 3000 ppm to groups of 50 male and 50 female Sprague-Dawley rats for 2 years. Body weights and food consumption we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3e82a34eded7ff0d4a49b7449dfd7dc
https://doi.org/10.1016/s0300-483x(98)00057-2
https://doi.org/10.1016/s0300-483x(98)00057-2
Autor:
Florence K. Kinoshita, Ward R. Richter, Richard S. Waritz, Marshall Steinberg, Catherine M. Kelly
Publikováno v:
Regulatory Toxicology and Pharmacology. 24:184-192
Historically, a direct and irreversible genotoxic reaction of a xenobiotic with DNA has been considered to be a universal and obligatory initiating event in the etiology of neoplasia, and it was assumed therefore that (1) there was no threshold other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f13985111beb28dc2772a21cf2da47a
https://doi.org/10.1006/rtph.1996.0124
https://doi.org/10.1006/rtph.1996.0124
Publikováno v:
Journal of the American College of Toxicology. 12:195-199
A single lifetime inhalation study of the effects of wholly vaporized unleaded gasoline has been conducted in the mouse. An elevation of hepatocellular tumors was reported only in females and only at the high treatment level (2056 ppm). Several repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::865ecba71b0a9b8a853190c41d5e5377
https://doi.org/10.3109/10915819309140639
https://doi.org/10.3109/10915819309140639
Publikováno v:
Journal of the American College of Toxicology. 12:119-126
An increased incidence of primary hepatocellular tumors was reported in female B6C3F1 mice following lifetime exposure to high levels (2056 ppm) of wholly vaporized unleaded gasoline. This effect was not observed in male mice, nor in females exposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95fd8d4c88800d291f37be9d18ece1b4
https://doi.org/10.3109/10915819309140630
https://doi.org/10.3109/10915819309140630
Autor:
Ward R. Richter, Joanne R. Kopplin
Publikováno v:
Pharmaceutical Sciences Encyclopedia
Outsourcing preclinical development and drug safety testing to Contract Research Organizations (CROs) has become very common in the biopharmaceutical, chemical, medical device, and food additive industries. Contract Research Organizations (CROs) cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0e5f1f74fa22aec19c9bba55944216
https://doi.org/10.1002/9780470571224.pse096
https://doi.org/10.1002/9780470571224.pse096
Autor:
Stuart Levin, Ward R. Richter
Publikováno v:
Toxicology and Applied Pharmacology. 27:680-684
A systematic method for the examination of urinary bladders in experimental animals has been devised. It consists of fixing the bladder in a partially distended state, methodically examining and dissecting it under a dissecting microscope, orienting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5782c2f6a1c6da04914a59304043e4
https://doi.org/10.1016/0041-008x(74)90047-7
https://doi.org/10.1016/0041-008x(74)90047-7
Publikováno v:
Toxicology and Applied Pharmacology. 35:137-145
Treatment of albino rats once daily for 6 weeks with graded doses of hexachlorophene led to pathologic changes in the white tracts of the central nervous system. These changes were dose related with respect to both incidence and severity and consiste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6a44b9150ad4b2dcbc4b0b7a42dea05
https://doi.org/10.1016/0041-008x(76)90119-8
https://doi.org/10.1016/0041-008x(76)90119-8
Autor:
Ward R. Richter, Sarah M. Moize
Publikováno v:
Journal of Ultrastructure Research. 9:1-9
During the course of our electron microscopic studies on the normal structure of transitional epithelium, we observed some characteristics of the cell wall which could provide for the epithelial stretching present in the distended urinary bladder. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c79d0fc7542588e167b6be11637ee15
https://doi.org/10.1016/s0022-5320(63)80032-5
https://doi.org/10.1016/s0022-5320(63)80032-5
Autor:
Ward R. Richter, John H. Thompson
Publikováno v:
Stain Technology. 35:145-148
A technique for hematoxylin-eosin staining in a Lipshaw tissue processor is described. Since the machine uses a 1 min minimum interval timer with a 20 min cycle and since the total time for the procedure is more than 20 min the timer must be permitte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e35cc791a47aef77a8efad8c7f5243c
https://doi.org/10.3109/10520296009114731
https://doi.org/10.3109/10520296009114731