Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Ward, Juma R R"'
Autor:
Ambler, Rachel, Edmunds, Grace, Tan, Sin Lih, Cirillo, Silvia, Pernes, Jane I., Ruan, Xiongtao, Huete-Carrasco, Jorge, Wong, Carissa C W, Lu, Jiahe, Ward, Juma R R, Toti, Giulia, Hedges, Alan J, Dovedi, Simon, Murphy, Robert F., Morgan, David, Wuelfing, Christoph
Publikováno v:
Ambler, R, Edmunds, G, Tan, S L, Cirillo, S, Pernes, J I, Ruan, X, Huete-Carrasco, J, Wong, C C W, Lu, J, Ward, J R R, Toti, G, Hedges, A J, Dovedi, S, Murphy, R F, Morgan, D & Wuelfing, C 2020, ' PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and tumor target cells within the tumor ', Science Signaling, vol. 13, no. 649, eaau4815 . https://doi.org/10.1101/443788, https://doi.org/10.1126/scisignal.aau4518
CD8+ T cell killing of tumor cells is suppressed by the tumor microenvironment. Inhibitory receptors, prominently PD-1, are key mediators of this suppression. To discover cellular defects triggered by tumor exposure and associated PD-1 signaling, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbbb5b80ae7644b8465cffb946a15ef
https://hdl.handle.net/1983/88e99fd9-00a0-40a1-ba18-83917301221a
https://hdl.handle.net/1983/88e99fd9-00a0-40a1-ba18-83917301221a