Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Wanzun Lin"'
Autor:
Ying Li, Jianmin Wang, Tingting Lin, Qin Ding, Youliang Weng, Wanzun Lin, Xiaosan Lin, Hanxuan Yang, Wenqian Xu, Hongmei Ying, Sufang Qiu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Background The landscape of the tumor microenvironment (TME) is intricately linked to the development of head and neck squamous cell carcinoma (HNSCC) and significantly influences immunotherapy efficacy. Recent research has underscored the pivotal ro
Externí odkaz:
https://doaj.org/article/f093237a56224e01aec2f0622cd7b15d
Autor:
Li Chen, Wanzun Lin, Haojiong Zhang, Shikai Geng, Ziyu Le, Fangzhu Wan, Qingting Huang, Huaiyuan Chen, Xingyu Liu, Jiade J. Lu, Lin Kong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-15 (2024)
Abstract Tribbles pseudokinase 3 (TRIB3) has been identified recently as a novel oncogene in several cancers. Still, further extensive research is imperative to elucidate its function and the molecular mechanisms underlying its involvement in the pro
Externí odkaz:
https://doaj.org/article/fd7ea6fe581c42ddb8e2d1dbd50e0f77
Autor:
Wanzun Lin, Li Chen, Haojiong Zhang, Xianxin Qiu, Qingting Huang, Fangzhu Wan, Ziyu Le, Shikai Geng, Anlan Zhang, Sufang Qiu, Long Chen, Lin Kong, Jiade J. Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
YTHDF1 is an m6A reader that binds to methylated RNA and facilitates translation. Here the authors show that tumor intrinsic YTHDF1 promotes tumorigenesis by regulating lysosomal proteolysis of MHC-I and that YTHDF1 targeting boosts anti-tumor immuni
Externí odkaz:
https://doaj.org/article/4b73dcf1c1ca49ba94758647df26f8a5
Autor:
Wanzun Lin, Jing Gao, Haojiong Zhang, Li Chen, Xianxin Qiu, Qingting Huang, Jiyi Hu, Lin Kong, Jiade J. Lu
Publikováno v:
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-15 (2022)
Abstract Background Inflammatory response is an important characteristic affecting prognosis and therapeutic response in lower-grade glioma (LGG). However, the molecular subtypes based on inflammatory response are still under exploitation. Methods Th
Externí odkaz:
https://doaj.org/article/e62ea722408c469bb9029cf80491ca82
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)
Abstract Background Malignant glioma, especially glioblastoma, is a highly aggressive disease with a dismal prognosis. Vacuole membrane protein 1 (VMP1) is a critical autophagy-associated protein with roles in oncogenesis and tumor progression. Howev
Externí odkaz:
https://doaj.org/article/f108516f102a4fb69b5816b2748e2af7
Publikováno v:
Molecular Therapy: Oncolytics, Vol 21, Iss , Pp 288-302 (2021)
Although the successful clinical trials of immunotherapy show promising strategies for many cancers, its application in glioma has lagged in comparison with the progress seen in other cancers. Both isocitrate dehydrogenase (IDH) mutations and 1p/19q
Externí odkaz:
https://doaj.org/article/7c4296df95ab45a1916e08630d4b118d
Autor:
Wanzun Lin, Yanyan Xu, Jing Gao, Haojiong Zhang, Yun Sun, Xianxin Qiu, Qingting Huang, Lin Kong, Jiade J. Lu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
B7 homolog 3 (B7-H3) is a recently found superfamily B7 molecule and therefore has significant involvement in immunological regulation. However, the relationships of B7-H3 expression with the tumor microenvironment (TME), response to immunotherapy, a
Externí odkaz:
https://doaj.org/article/e6661a7e03ca4ccfaa48fa044b332c9c
Autor:
Xiaochuan Chen, Chao Li, Ying Li, Shihong Wu, Wei Liu, Ting Lin, Miaomiao Li, Youliang Weng, Wanzun Lin, Sufang Qiu
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Glioma is the most common and aggressive type of primary brain malignant tumor with limited treatment approaches. Methyltransferase-like 7B (METTL7B) is associated with the pathogenesis of several diseases but is rarely studied in glioma. In this stu
Externí odkaz:
https://doaj.org/article/96812b2fa3f9431ab2c9440bbf361fbe
Autor:
Xinwen Wang, Liangming Wang, Weifeng Xu, Xinwu Wang, Dianshan Ke, Jinluan Lin, Wanzun Lin, Xiaochun Bai
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Accumulating evidence has supported that osteosarcoma is heterogeneous, and several subtypes have been identified based on genomic profiling. Immunotherapy is revolutionizing cancer treatment and is a promising therapeutic strategy. In contrast, few
Externí odkaz:
https://doaj.org/article/9131d5d0fab243c79fa88f11808ffa6c
Autor:
Wanzun Lin, Jun Liu, Juhui Chen, Jiancheng Li, Sufang Qiu, Jiayu Ma, Xiandong Lin, Lurong Zhang, Junxin Wu
Publikováno v:
EBioMedicine, Vol 49, Iss , Pp 133-144 (2019)
Background: Active immunotherapy is an effective, long-lasting, cheap, and safe approach to suppress cancer progression; however, the key issue is to develop appropriate tumour vaccines. Oncoproteins are up-regulated under various stress conditions a
Externí odkaz:
https://doaj.org/article/3991a138c8004462970ae103ebafb029