Výsledky vyhledávání - "Wanxiangfu Tang"

Akademický článek

Predicting Disease Progression in Inoperable Localized NSCLC Patients Using ctDNA Machine Learning Model

Autor: Yuqi Wu, Canjun Li, Yin Yang, Tao Zhang, Jianyang Wang, Wanxiangfu Tang, Ningyou Li, Hua Bao, Xin Wang, Nan Bi

Publikováno v: Cancer Medicine, Vol 13, Iss 20, Pp n/a-n/a (2024)

ABSTRACT Introduction There is an urgent clinical need to accurately predict the risk for disease progression in post‐treatment NSCLC patients, yet current ctDNA mutation profiling approaches are limited by low sensitivity. We represent a non‐inv

Externí odkaz: https://doaj.org/article/0e221c502cc74284abf3e3200c4af352

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Akademický článek

Comprehensive characterization of PKHD1 mutation in human colon cancer

Autor: Lu Han, Fangming Gong, Xuxiaochen Wu, Wanxiangfu Tang, Hua Bao, Yue Wang, Daizhenru Wang, Yulan Sun, Peng Li

Publikováno v: Cancer Medicine, Vol 13, Iss 1, Pp n/a-n/a (2024)

Abstract Introduction The PKHD1 (Polycystic Kidney and Hepatic Disease 1) gene is essential for producing fibrocystin or polyductin, which is crucial in various cellular functions. Mutations in PKHD1 have been found to be involved in the development

Externí odkaz: https://doaj.org/article/44fab72189964ca4bc6df256723e7967

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Akademický článek

Letter to the Editor: An ultra-sensitive assay using cell-free DNA fragmentomics for multi-cancer early detection

Publikováno v: Molecular Cancer, Vol 21, Iss 1, Pp 1-7 (2022)

Abstract Early detection can benefit cancer patients with more effective treatments and better prognosis, but existing early screening tests are limited, especially for multi-cancer detection. This study investigated the most prevalent and lethal can

Externí odkaz: https://doaj.org/article/2dcf7893a71f4321bbdf88e3c6d002b5

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Akademický článek

Multi-dimensional fragmentomic assay for ultrasensitive early detection of colorectal advanced adenoma and adenocarcinoma

Autor: Xiaoji Ma, Yikuan Chen, Wanxiangfu Tang, Hua Bao, Shaobo Mo, Rui Liu, Shuyu Wu, Hairong Bao, Yaqi Li, Long Zhang, Xue Wu, Sanjun Cai, Yang Shao, Fangqi Liu, Junjie Peng

Publikováno v: Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-4 (2021)

Abstract Previous studies on liquid biopsy-based early detection of advanced colorectal adenoma (advCRA) or adenocarcinoma (CRC) were limited by low sensitivity. We performed a prospective study to establish an integrated model using fragmentomic pro

Externí odkaz: https://doaj.org/article/73ad0b933794424d86201cbe0647e394

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Akademický článek

L1 retrotransposons exploit RNA m6A modification as an evolutionary driving force

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

L1 is a group of active retrotransposons in humans. Here the authors show that m6A modifications on L1 RNA increase translation efficiency and retrotransposition in human cells. M6A motifs are more enriched in evolutionary young L1s.

Externí odkaz: https://doaj.org/article/1961d00465714c29a8b1bed8e65a3309

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Akademický článek

Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma

Autor: Yan Huang, Xi Chen, Hua Bao, Xue Wu, Hongyun Zhao, Shaodong Hong, Yunpeng Yang, Wenfeng Fang, Yuxiang Ma, Yang Shao, Ao Wang, Qingguang Lin, Wanxiangfu Tang

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)

Background Anti-programmed death (PD)-1 therapy has recently been used in recurrent or metastatic (R/M) nasopharyngeal carcinoma (NPC). The long-term survival and its biomarkers responding to anti-PD-1 treatment in patients with R/M NPC remain unclea

Externí odkaz: https://doaj.org/article/2787801fbb5e49ca9398c379fbfb7449

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