Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Wanwen Lan"'
Autor:
Aihua Hou, Wanwen Lan, Kai Pong Law, Ser Chin Jasmine Khoo, Min Qi Tin, Yoon Pin Lim, Louis Tong
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97402 (2014)
PURPOSE: Pterygium is a wing shaped fibrovascular growth on the ocular surface, characterized by fibrosis, angiogenesis, extracellular matrix remodeling, and inflammatory infiltrates. Epidemiologic studies have linked pterygium formation to various c
Externí odkaz:
https://doaj.org/article/31f9e314bf0d4d249c9c859433b2839d
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
Dry eye is a common health problem worldwide, causing significant discomfort and inconvenience to sufferers. The conventional treatment of dry eye via topical administration of eye drops is deemed palliative and unsatisfactory to many. Traditional Ch
Externí odkaz:
https://doaj.org/article/d251428619e04f5689046895249496d0
Autor:
Andri K Riau, Tina T Wong, Wanwen Lan, Sharon N Finger, Shyam S Chaurasia, Ai Hua Hou, Silin Chen, Shang Juan Yu, Louis Tong
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14687 (2011)
BACKGROUND: Pterygium is a common ocular surface disease characterized by abnormal epithelial and fibrovascular proliferation, invasion, and matrix remodeling. This lesion, which migrates from the periphery to the center of the cornea, impairs vision
Externí odkaz:
https://doaj.org/article/dace3dddf8ad4236b2270a83abf24fc2
Publikováno v:
FEBS letters. 592(7)
Long intergenic noncoding RNAs (lincRNAs) are not fully characterized in disease, although many are involved in controlling differentiation. We discovered and sequenced a novel 4.4 kb human lincRNA called linc-9432 in pterygium, an ocular disease cha
Publikováno v:
The Ocular Surface. 12:23-31
The S100 proteins are calcium-binding proteins that are exclusively expressed in vertebrates, where they interact with enzymes, cytoskeletal proteins, receptors, transcription factors, and nucleic acids to regulate proliferation, differentiation, apo
Autor:
Evelyn Png1, WanWen Lan1, Melisa Lazaroo1,2, Silin Chen1, Lei Zhou1, Louis Tong1,3,4 Louis.tong.h.t@snec.com.sg
Publikováno v:
Analytical & Bioanalytical Chemistry. Jul2011, Vol. 400 Issue 3, p767-775. 9p. 2 Diagrams, 1 Chart, 3 Graphs.
Publikováno v:
Medical Hypotheses. 81:927-930
Pterygium is a fibrovascular proliferative condition of the ocular surface with no known pathological mechanism. This condition affects vision due to dry eyes, astigmatism or physical occlusion of the visual axis for severe cases. The only definitive
Publikováno v:
The Ocular Surface. 10:137-148
The nuclear factor-κB (NF-κB) is a key transcription factor pathway that is responsible for many key biological processes, such as inflammation, apoptosis, stress response, corneal wound healing, angiogenesis, and lymphangiogenesis. Numerous recent
Publikováno v:
The Ocular Surface. 9:212-226
Many drugs used for chronic illnesses can contribute to dry eye syndrome, and elderly patients who have dry eye may concurrently be on systemic medications that worsen the condition. Such medications include anticholinergic drugs, eg, antidepressant,
Publikováno v:
Analytical and Bioanalytical Chemistry. 400:767-775
Transglutaminase (TGM)-2 is a ubiquitous protein with important cellular functions such as regulation of cytoskeleton, cell adhesion, apoptosis, energy metabolism, and stress signaling. We identified several proteins that may interact with TGM-2 thro