Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Wanwei Sun"'
Autor:
Guimin Zhao, Yanqi Li, Tian Chen, Feng Liu, Yi Zheng, Bingyu Liu, Wei Zhao, Xiaopeng Qi, Wanwei Sun, Chengjiang Gao
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011902 (2024)
Fungal infections have emerged as a major concern among immunocompromised patients, causing approximately 2 million deaths each year worldwide. However, the regulatory mechanisms underlying antifungal immunity remain elusive and require further inves
Externí odkaz:
https://doaj.org/article/60bf1e39a0a04c29b883199e9226c753
Autor:
Yanyun Du, Qianwen Peng, Du Cheng, Ting Pan, Wanwei Sun, Heping Wang, Xiaojian Ma, Ruirui He, Huazhi Zhang, Zhihui Cui, Xiong Feng, Zhiqiang Liu, Tianxin Zhao, Wenjun Hu, Lei Shen, Wenyang Jiang, Na Gao, Bradley N. Martin, Cun-Jin Zhang, Zhanguo Zhang, Chenhui Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Cancer cells producing ligands for the immune checkpoint molecules PD-1 and CTLA-4 is an important mechanism of tumour immune resistance. Here authors show that BTNL2 expression on cancer cells generates a dysfunctional tumour immune microenvironment
Externí odkaz:
https://doaj.org/article/bc2c48f5c4eb46b6b81e3b0918f911d1
Autor:
Yanyun Du, Rui Shi, Ying Zhang, Xiaomin Duan, Li Li, Jing Zhang, Fengze Wang, Ruixue Zhang, Hao Shen, Yue Wang, Zheng Wu, Qianwen Peng, Ting Pan, Wanwei Sun, Weijin Huang, Yue Feng, Hui Feng, Junyu Xiao, Wenjie Tan, Youchun Wang, Chenhui Wang, Jinghua Yan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Here the authors report the isolation and structural and biological characterization of a humanized angiotensin-converting enzyme 2 (ACE2)-blocking antibody, which exterts potent inhibitory activity against SARS-CoV and circulating global SARS-CoV-2
Externí odkaz:
https://doaj.org/article/97a9b5fb5db54f02ba7db4036da85f1f
Autor:
Jianwen Chen, Ruirui He, Wanwei Sun, Ru Gao, Qianwen Peng, Liwen Zhu, Yanyun Du, Xiaojian Ma, Xiaoli Guo, Huazhi Zhang, Chengcheng Tan, Junhan Wang, Wei Zhang, Xiufang Weng, Jianghong Man, Hermann Bauer, Qing K. Wang, Bradley N. Martin, Cun-Jin Zhang, Xiaoxia Li, Chenhui Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
TAGAP gene variants are linked to human autoimmunity. Here the authors identify TAGAP as a Dectin-1 and EphB2-binding protein mediating antifungal innate immune signaling and cytokine production, and demonstrate TAGAP in non-T cells promotes Th17 res
Externí odkaz:
https://doaj.org/article/69258493889b41e28feb66c907a43116
Autor:
Yi Gong, Xiaoyuan Wei, Wanwei Sun, Xin Ren, Jiao Chen, Jude Juventus Aweya, Hongyu Ma, Kok-Gan Chan, Yueling Zhang, Shengkang Li
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009837 (2021)
It is well known that exosomes could serve as anti-microbial immune factors in animals. However, despite growing evidences have shown that the homeostasis of the hemolymph microbiota was vital for immune regulation in crustaceans, the relationship be
Externí odkaz:
https://doaj.org/article/d6d5388b7c24422aaa85b398d0157f92
Autor:
Chuping Xie, Yaping Chen, Wanwei Sun, Jun Ding, Lizhen Zhou, Shasha Wang, Shuqi Wang, Yueling Zhang, Dashi Zhu, Xiaobo Wen, Songnian Hu, Shengkang Li
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114500 (2014)
Mud crab Scylla paramamosain is an economically important marine species in China. However, frequent outbreaks of infectious diseases caused by marine bacteria, such as Vibrio parahaemolyticus, result in great economic losses.Comparative de novo tran
Externí odkaz:
https://doaj.org/article/4c95c01e43084fa19f26dca446f5229b
Autor:
Huazhi Zhang, Zhihui Cui, Ting Pan, Huijun Hu, Ruirui He, Ming Yi, Wanwei Sun, Ru Gao, Heping Wang, Xiaojian Ma, Qianwen Peng, Xiong Feng, Shuyan Liang, Yanyun Du, Chenhui Wang
Publikováno v:
J Immunol
The receptor tyrosine kinase EPHB2 (EPH receptor B2) is highly expressed in many human cancer types, especially in gastrointestinal cancers, such as colorectal cancer. Several coding mutations of the EPHB2 gene have been identified in many cancer typ
Autor:
Fei Qin, Baoshan Cai, Runyu Cao, Xuemei Bai, Jiahua Yuan, Yuling Zhang, Yaxing Liu, Tian Chen, Feng Liu, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 12/26/2023, Vol. 120 Issue 52, p1-12, 31p
Autor:
Xiaojian Ma, Xi Tan, Bingbing Yu, Wanwei Sun, Heping Wang, Huijun Hu, Yanyun Du, Ruirui He, Ru Gao, Qianwen Peng, Zhihui Cui, Ting Pan, Xiong Feng, Junhan Wang, Chengqi Xu, Bin Zhu, Wei Liu, Chenhui Wang
Publikováno v:
Cellular and Molecular Immunology
Fungal infections cause ~1.5 million deaths each year worldwide, and the mortality rate of disseminated candidiasis currently exceeds that of breast cancer and malaria. The major reasons for the high mortality of candidiasis are the limited number of
Autor:
Xiaojian Ma, Zhihui Cui, Yue-Ying Wang, Songfang Wu, Yanyun Du, Huazhi Zhang, Ruirui He, Liwen Zhu, Cun-Jin Zhang, Chenhui Wang, Bradley N. Martin, Qianwen Peng, Heping Wang, Ru Gao, Jianwen Chen, Huijun Hu, Wanwei Sun
Publikováno v:
The Journal of Immunology. 206:2353-2365
IL-17A plays an essential role in the pathogenesis of many autoimmune diseases, including psoriasis and multiple sclerosis. Act1 is a critical adaptor in the IL-17A signaling pathway. In this study, we report that an anti-sense long noncoding RNA, TR