Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Wanwan Shen"'
Autor:
Lei Wang, Zhu Chen, Yang Xiao, Xiao Shang, Haidong Liu, Wanwan Shen, Baiteng Zhao, Guobao Wang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/c9fc09e8e7fb4775baa884901e169e3d
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/6c9d138e9aab4d048fff220c1cfb410e
Autor:
Yunqian Qiao, Yangmin Qiu, Jie Ding, Nana Luo, Hao Wang, Xiaomin Ling, Jiya Sun, Zhihai Wu, Yisen Wang, Yanpeng Liu, Feifei Guo, Ta Sun, Wanwan Shen, Min Zhang, Dongdong Wu, Bingliang Chen, Wei Xu, Xuan Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The toxicity arising from generalised stimulation of T cells restricts applicability of CD137 agonists in cancer immune therapy. Here authors show that a bispecific antibody blocking PD-1 while activating CD137 efficiently restricts T cell activation
Externí odkaz:
https://doaj.org/article/5a74607a784c4173b05f771b90d4abb5
Publikováno v:
ACS Central Science, Vol 4, Iss 10, Pp 1326-1333 (2018)
Externí odkaz:
https://doaj.org/article/3300c0154cc9480c9af188b53ba0b7ec
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Proteins can serve as means of medical treatment, but their efficient delivery to cells is difficult. Here, the authors present a type of polymers, fluoroamphiphiles, acting as chemical chaperones that can facilitate the import of proteins into the i
Externí odkaz:
https://doaj.org/article/fad39cd185194ad39cc2d484c2bd4eb0
Autor:
Dongdong Wu, Yanpeng Liu, Xuan Wang, Ta Sun, Zhihai Wu, Yangmin Qiu, Jie Ding, Nana Luo, Yisen Wang, Yunqian Qiao, Wei Xu, Jiya Sun, Xiaomin Ling, Hao Wang, Feifei Guo, Wanwan Shen, Min Zhang, Bingliang Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
Expression of the cell surface receptor CD137 has been shown to enhance anti-cancer T cell function via engagement with its natural ligand 4-1BBL. CD137 ligation with engineered ligands has emerged as a cancer immunotherapy strategy, yet clinical dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2470532a839f4f4270968d8f3a43279b
https://doaj.org/article/5a74607a784c4173b05f771b90d4abb5
https://doaj.org/article/5a74607a784c4173b05f771b90d4abb5
Publikováno v:
CCS Chemistry. 2:146-157
There is a continuing quest to rationally fabricate polymeric biomaterials with both high transfection efficiency and minimal toxicity for the emerging opportunities in small interfering RNA (siRNA...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85b99adcb142245842d9cd52d0cdeed4
https://doi.org/10.31635/ccschem.020.201900084
https://doi.org/10.31635/ccschem.020.201900084
Publikováno v:
Journal of materials chemistry. B. 4(34)
Lipid modification has been widely applied to improve the gene delivery efficacy of cationic polymers. However, this strategy is often associated with relatively low efficacy and high toxicity due to the inherent features of lipids. Here, we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a337817e4016bda4afee28a90e8b3657
https://pubmed.ncbi.nlm.nih.gov/32263857
https://pubmed.ncbi.nlm.nih.gov/32263857
Publikováno v:
Journal of materials chemistry. B. 6(44)
Fluoropolymers have shown great promise in non-viral gene delivery. The current fluoropolymers developed for gene delivery are synthesized by grafting fluoroalkyls or fluoroaromatics onto cationic polymers. To expand the family of fluoropolymers for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b866a3c5968899baf3f8226f0e5f6fa5
https://pubmed.ncbi.nlm.nih.gov/32254635
https://pubmed.ncbi.nlm.nih.gov/32254635
Publikováno v:
Gene Therapy
Single-strand oligonucleotides provide promising potential as new therapeutics towards various diseases. However, the efficient delivery of oligonucleotide therapeutics is still challenging due to their susceptibility to nuclease degradation and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371aa5b2e054cf9cb07df5882188d23a
https://pubmed.ncbi.nlm.nih.gov/32366887
https://pubmed.ncbi.nlm.nih.gov/32366887