Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Wantanee Phuapradit"'
Autor:
Harpreet Sandhu, Siva Ram Kiran Vaka, Dipen Desai, Paras Jariwala, Aruna Railkar, Wantanee Phuapradit, Navnit Shah
Publikováno v:
Oral Drug Delivery for Modified Release Formulations. :181-204
Autor:
Wantanee Phuapradit, Siva Ram Kiran Vaka, Navnit Hargovindas Shah, Waseem Malick, Dipen Desai, Sandhu Harpreet K, Hossein Zia
Publikováno v:
Journal of pharmaceutical sciences. 107(1)
The objective of the study was to select solid-state plasticizers for hot-melt extrusion (HME) process. The physical and mechanical properties of plasticizers, in selected binary (polymer:plasticizer) and ternary (active pharmaceutical ingredient:pol
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 53:175-179
The use of a wax-based vehicle is one approach to stabilize a drug which is susceptible to hydrolysis and/or oxidation. The drug used in the study, as a microfine powder, is dispersed in the wax mixture and encapsulated in a soft gelatin capsule. To
Autor:
M. Serpil Kislalioglu, Wantanee Phuapradit, Ketan A. Mehta, A. Waseem Malick, Navnit Hargovindas Shah
Publikováno v:
Drug Development and Industrial Pharmacy. 28:275-285
Nifedipine (N) and nifedipine. Pluronic F-68 solid dispersion (SD) pellets were developed and characterizedfor drug release mechanisms from a multi-unit erosion matrix system for controlled release. Nifedipine was micronized using a jet mill. Solid d
Autor:
Jelena Djordjevic, Murali Mohan Bommana, Dipen Desai, Navnit Hargovindas Shah, Siva Ram Kiran Vaka, Wantanee Phuapradit
Publikováno v:
Advances in Delivery Science and Technology ISBN: 9781493915972
Pharmaceutical excipients play a significant role in stabilization of amorphous solid dispersions, as these systems are thermodynamically unstable. This chapter illustrates the challenges associated with amorphous solid dispersion stability and the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e11f2111b964f550caeda805ed2691d7
https://doi.org/10.1007/978-1-4939-1598-9_4
https://doi.org/10.1007/978-1-4939-1598-9_4
Release performance of a poorly soluble drug from a novel, Eudragit®-based multi-unit erosion matrix
Publikováno v:
International Journal of Pharmaceutics. 213:7-12
Mechanisms governing the release of drugs from controlled delivery systems are mainly diffusion, osmosis and erosion. For poorly soluble drugs, the existing mechanisms are limited to osmosis and matrix erosion, that are commonly observed in single un
Autor:
Wantanee Phuapradit, Ketan A. Mehta, M. Serpil Kislalioglu, Navnit Hargovindas Shah, A. Waseem Malick
Publikováno v:
Journal of Controlled Release. 63:201-211
The effect of drug loading, water required for granulation and spheronization time on porosity parameters (intrusion-extrusion isotherms, pore size distribution, total pore surface area, mean pore diameter, shape and morphology of pores) and drug rel
Publikováno v:
Drug Development and Industrial Pharmacy. 21:955-963
The application of a polymer film coat is a common practice in the preparation of controlled release dosage forms. In vitro characterization of the polymeric membrane is essential for optimization of the membrane formulation. Polymers selected in thi
Autor:
Wantanee Phuapradit, Albano Antonio A, Duk Soon Choi, Hung Tian, Harpreet K. Sandhu, Shalini Anand, Navnit Hargovindas Shah, K. Tang, Rodolfo Pinal, Raman Mahadevan Iyer, Ashish Chatterji, Hitesh Chokshi, Waseem Malick, Dharmendra Singhal
Publikováno v:
International journal of pharmaceutics. 438(1-2)
A novel method was developed to manufacture amorphous formulations of poorly soluble compounds that cannot be processed with existing methods such as spray drying and melt extrusion. The manufacturing process and the characterization of the resulting
Autor:
K. Iqbal, Martin Howard Infeld, Maria Oksana Bachynsky, Wantanee Phuapradit, Navnit Hargovindas Shah, A. W. Malick
Publikováno v:
Drug Development and Industrial Pharmacy. 20:873-888
Bioavailability of a sparingly soluble drug is often limited by the rate of dissolution of the drug substance. The drug in a micronized form is generally employed to maximize the bioavailability. However, the micronized drugs tend to agglomerates and