Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Wanshan Ning"'
Autor:
Zhicheng Wang, Ying Gu, Lindan Huang, Shuai Liu, Qun Chen, Yunyun Yang, Guolin Hong, Wanshan Ning
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Cardiovascular disease, also known as circulation system disease, remains the leading cause of morbidity and mortality worldwide. Traditional methods for diagnosing cardiovascular disease are often expensive and time-consuming. So
Externí odkaz:
https://doaj.org/article/e2910fd8eb684a019908ecf6d7f01a9d
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2507-2515 (2024)
The incidence of early-onset colorectal cancer (EOCRC) has increased significantly worldwide. Uncovering biomarkers that are unique to EOCRC is of great importance to facilitate the prevention and detection of this growing cancer subtype. Although ef
Externí odkaz:
https://doaj.org/article/dcc0958b88474c11aeb05b8bcec8ed69
Autor:
Qihong Chen, Ruizhi Xu, Ying Gu, Jie Peng, Chiyuan Ma, Dubin Su, Shuai Liu, Dandan Ge, Yungang Yang, Wanshan Ning
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundTo counteract the COVID-19 pandemic, nonpharmaceutical interventions (NPIs) were implemented globally, exerting a profound influence on a wide spectrum of infectious diseases, encompassing respiratory tract infections (RTIs). Subsequent to
Externí odkaz:
https://doaj.org/article/a3ea14016cda448783d734b81d9d986b
Autor:
Ke Shui, Chenwei Wang, Xuedi Zhang, Shanshan Ma, Qinyu Li, Wanshan Ning, Weizhi Zhang, Miaomiao Chen, Di Peng, Hui Hu, Zheng Fang, Anyuan Guo, Guanjun Gao, Mingliang Ye, Luoying Zhang, Yu Xue
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Proteostasis is fundamental for maintaining organismal health. However, the mechanisms underlying its dynamic regulation and how its disruptions lead to diseases are largely unclear. Here, we conduct in-depth propionylomic profiling in Droso
Externí odkaz:
https://doaj.org/article/2db3598d0d114b6193e54fc623e0473a
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundOvarian cancer (OC) is a highly heterogeneous and malignant gynecological cancer, thereby leading to poor clinical outcomes. The study aims to identify and characterize clinically relevant subtypes in OC and develop a diagnostic model that
Externí odkaz:
https://doaj.org/article/4c865c5dda834c3e95932d91d5ade36a
Autor:
Zhu Han, Weizhi Zhang, Wanshan Ning, Chenwei Wang, Wankun Deng, Zhidan Li, Zehua Shang, Xiaofei Shen, Xiaohui Liu, Otto Baba, Tsuyoshi Morita, Lu Chen, Yu Xue, Da Jia
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Although autophagy has been linked to tumourigenesis, it is unclear how genomic alterations affect autophagy selectivity in tumours. Here, the authors establish a pipeline that integrates computational and experimental approaches to show that altered
Externí odkaz:
https://doaj.org/article/b297a2c17e62427299d5a53ccf1dcfaa
Autor:
Peiran Jiang, Wanshan Ning, Yunshu Shi, Chuan Liu, Saijun Mo, Haoran Zhou, Kangdong Liu, Yaping Guo
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4497-4509 (2021)
As a novel lactate-derived post-translational modification (PTM), lysine lactylation (Kla) is involved in diverse biological processes, and participates in human tumorigenesis. Identification of Kla substrates with their exact sites is crucial for re
Externí odkaz:
https://doaj.org/article/9d6f39c1d50848bfbdccb612ae628a81
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 18, Iss 2, Pp 194-207 (2020)
As an important protein acylation modification, lysine succinylation (Ksucc) is involved in diverse biological processes, and participates in human tumorigenesis. Here, we collected 26,243 non-redundant known Ksucc sites from 13 species as the benchm
Externí odkaz:
https://doaj.org/article/20d3c8addff14278a866d6ec1a8b0b37
Autor:
Yaping Guo, Wanshan Ning, Peiran Jiang, Shaofeng Lin, Chenwei Wang, Xiaodan Tan, Lan Yao, Di Peng, Yu Xue
Publikováno v:
Cells, Vol 9, Iss 5, p 1266 (2020)
Protein phosphorylation is essential for regulating cellular activities by modifying substrates at specific residues, which frequently interact with proteins containing phosphoprotein-binding domains (PPBDs) to propagate the phosphorylation signaling
Externí odkaz:
https://doaj.org/article/f363363bd4c543a3994c5861edd398a4
Autor:
Miaomiao Chen, Weizhi Zhang, Yujie Gou, Danyang Xu, Yuxiang Wei, Dan Liu, Cheng Han, Xinhe Huang, Chengzhi Li, Wanshan Ning, Di Peng, Yu Xue
Publikováno v:
Nucleic Acids Research.
Protein phosphorylation, catalyzed by protein kinases (PKs), is one of the most important post-translational modifications (PTMs), and involved in regulating almost all of biological processes. Here, we report an updated server, Group-based Predictio