Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Wanqu ZHU"'
Autor:
Leng Ni, Lijuan Liu, Wanqu Zhu, Richard Telljohann, Jing Zhang, Robert E. Monticone, Kimberly R. McGraw, Changwei Liu, Christopher H. Morrell, Pablo Garrido‐Gil, Jose Luis Labandeira‐Garcia, Edward G. Lakatta, Mingyi Wang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 17 (2022)
Background Age‐associated aortic remodeling includes a marked increase in intimal medial thickness (IMT), associated with signs of inflammation. Although aortic wall milk fat globule–epidermal growth factor VIII (MFG‐E8) increases with age, and
Externí odkaz:
https://doaj.org/article/bf073e5d078f47adae6b593d9d3cd4ae
Autor:
Mingyi Wang, Li Zhang, Wanqu Zhu, Jing Zhang, Soo Hyuk Kim, Yushi Wang, Leng Ni, Richard Telljohann, Robert E. Monticone, Kimberly McGraw, Lijuan Liu, Rafael de Cabo, Edward G. Lakatta
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 18 (2018)
Background Aging exponentially increases the incidence of morbidity and mortality of quintessential cardiovascular disease mainly due to arterial proinflammatory shifts at the molecular, cellular, and tissue levels within the arterial wall. Calorie r
Externí odkaz:
https://doaj.org/article/1cb3608c3ec6469ea847c976e5e863a8
Autor:
Mingyi Wang, richard telljohann, Leng Ni, Wanqu ZHU, Soo hyuk Kim, Lijuan Liu, JING ZHANG, Kimberly McGraw, Robert Monticone, Christopher Morrell, Edward G Lakatta
Publikováno v:
Circulation. 144
Background: Milk fat globule epidermal growth factor VIII (MFG-E8), a secreted membrane glycoprotein, is an inflammatory signaling molecule, promoting the proliferation and invasion of vascular smooth muscle cells in vitro. MFG-E8 also is a bridging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3b4794537e588549fb259527a3cff28
https://doi.org/10.1161/circ.144.suppl_1.9460
https://doi.org/10.1161/circ.144.suppl_1.9460
Autor:
Leng Ni, Lijuan Liu, Wanqu Zhu, Richard Telljohann, Jing Zhang, Robert E. Monticone, Kimberly R. McGraw, Changwei Liu, Christopher H. Morrell, Pablo Garrido-Gil, Jose Luis Labandeira-Garcia, Edward G. Lakatta, Mingyi Wang
BackgroundAngiotensin II (Ang II) and milk fat globule-epidermal growth factor VIII (MFG-E8) are involved in age-associated arterial remodeling; however, the inflammatory role of MFG-E8 in Ang II associated arterial remodeling with aging remains unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54c7fa71fb107400e24a1e1b78e4f433
https://doi.org/10.1101/2021.03.11.434767
https://doi.org/10.1101/2021.03.11.434767
Autor:
Jing Zhang, Robert E. Monticone, Soo Hyuk Kim, Roberta Giordo, Kimberly R. McGraw, Leng Ni, Richard Telljohann, Lijuan Liu, Wanqu Zhu, Gianfranco Pintus, Yushi Wang, Li Zhang, Chloe Ferris, Edward G. Lakatta, Mingyi Wang
Publikováno v:
Oncotarget. 9:27117-27132
The glycosylated protein vasorin physically interacts with the transforming growth factor-beta1 (TGF-β1) and functionally attenuates its fibrogenic signaling in the vascular smooth muscle cells (VSMCs) of the arterial wall. Angiotensin II (Ang II) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b50db39abf3af878938de697208f63
https://doi.org/10.18632/oncotarget.25499
https://doi.org/10.18632/oncotarget.25499
Autor:
Steven S. An, Edwin J. Yoo, Reynold A. Panettieri, Gaoyuan Cao, Wanqu Zhu, Christie A. Ojiaku, Blanca E. Himes, Maya Shumyatcher
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 58:575-584
Transforming growth factor β1 (TGF-β1), a cytokine whose levels are elevated in the airways of patients with asthma, perpetuates airway inflammation and modulates airway structural cell remodeling. However, the role of TGF-β1 in excessive airway n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e356a601467b33b27f78c087ca412603
https://doi.org/10.1165/rcmb.2017-0247oc
https://doi.org/10.1165/rcmb.2017-0247oc
Autor:
Jessie Huang, Byoung Choul Kim, Edward G. Lakatta, Mingyi Wang, Robert E. Monticone, Taekjip Ha, Abraham Isak, Steven S. An, Natalia Marchesan Bexiga, Wanqu Zhu
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Here we report exquisitely distinct material properties of primary vascular smooth muscle (VSM) cells isolated from the thoracic aorta of adult (8 months) vs. aged (30 months) F344XBN rats. Individual VSM cells derived from the aged animals showed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68e72840800c69f29f1d0019bc0b84b
http://link.springer.com/article/10.1038/s41598-018-20763-w
http://link.springer.com/article/10.1038/s41598-018-20763-w
Autor:
Siqi Tan, Sebastian F. Barreto-Ortiz, Robert N. Cole, Huilei Wang, Dan E. Berkowitz, Tatiana Boronina, Marc K. Halushka, Sandeep Jandu, Lakshmi Santhanam, Marcel J. Rauer, Kavitha Nandakumar, Steven S. An, Wanqu Zhu, Yehudit Bergman, Jochen Steppan
Publikováno v:
Am J Physiol Heart Circ Physiol
Vascular stiffening and its sequelae are major causes of morbidity and mortality in the elderly. The increasingly accepted concept of “smooth muscle cell (SMC) stiffness syndrome” along with matrix deposition has emerged in vascular biology to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a310d0ecc15dbdc1f1fc3c708a42140
https://europepmc.org/articles/PMC6692735/
https://europepmc.org/articles/PMC6692735/
Autor:
Lijuan Liu, Li Zhang, Mingyi Wang, Wanqu Zhu, Leng Ni, Jing Zhang, Richard Telljohann, Edward G. Lakatta, Rafael de Cabo, Soo Hyuk Kim, Yushi Wang, Kimberly R. McGraw, Robert E. Monticone
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Aging exponentially increases the incidence of morbidity and mortality of quintessential cardiovascular disease mainly due to arterial proinflammatory shifts at the molecular, cellular, and tissue levels within the arterial wall. Calorie r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5276dffc9d51c3ac7a4cebc8b33dfa4c
https://doi.org/10.1161/jaha.117.004303
https://doi.org/10.1161/jaha.117.004303
Autor:
Reynold A. Panettieri, A-Rum Yoon, Cruz R, Steven S. An, Wanqu Zhu, De Santiago B, Oliver Homann, William H. Aisenberg, Hwan Mee Yong, Stephen B. Liggett, Jennifer L. Pluznick, Rajkumar P, Lakshmi Santhanam, Oh Jj, Sullivan Jk, Niranjana Natarajan, Jessie Huang
Publikováno v:
Scientific Reports
Pathways that control, or can be exploited to alter, the increase in airway smooth muscle (ASM) mass and cellular remodeling that occur in asthma are not well defined. Here we report the expression of odorant receptors (ORs) belonging to the superfam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d6faeba24a255808c94f991162e52a