Zobrazeno 1 - 10
of 841
pro vyhledávání: '"Wanqing WU"'
Autor:
Xiangwen Tan, Yaru Jing, Jiahao Wu, Jiatian Li, Zhenjie Yang, Wanqing Wu, Zhuofeng Ke, Huanfeng Jiang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Palladium-catalyzed directed C − H functionalization/cyclization is an effective approach for synthesizing nitrogen heterocycles. Imine, known for its ease of installation/removal, has been extensively used in the C–H activation of aldeh
Externí odkaz:
https://doaj.org/article/e54409c32e6d4d2089a29b02aa821116
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Palladium catalyzed tandem reaction represents a one-pot synthetic approach to efficiently synthesize complex functionalized molecules while reducing synthetic steps, aligning with the principles of green chemistry. However, achieving a dire
Externí odkaz:
https://doaj.org/article/a374d38d57274a319a3897d0fd0cb159
Autor:
Kanghui Duan, Fuxing Tan, Hongming Xie, Haiwang Liu, Yingjun Zhang, Huanfeng Jiang, Wanqing Wu
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100203- (2024)
In this study, 56 isoxazole derivatives were synthesized and their antitumor activity against 9 cancer cells, such as BXPC-3, MiaPaCa-2, PANC-1, MCF-7, HCT-116, HepG2, NCI-H460, A549 and B16 was detected. The results of pharmacological experiments in
Externí odkaz:
https://doaj.org/article/0adbbff9568d40c1bbc1e9fffb5099eb
Publikováno v:
Applied Artificial Intelligence, Vol 38, Iss 1 (2024)
ABSTRACTPeripheral blood cell detection is an essential component of medical practice and is used to diagnose and treat diseases, as well as to monitor the progress of therapies. Our objective is to construct an efficient deep learning model for peri
Externí odkaz:
https://doaj.org/article/d68520b5b8ec453399acada3bfa82ddb
Autor:
Jie Wu, Zhenxu Xiao, Mengjing Wang, Wanqing Wu, Xiaoxi Ma, Xiaoniu Liang, Li Zheng, Saineng Ding, Jianfeng Luo, Yang Cao, Zhen Hong, Jing Chen, Qianhua Zhao, Ding Ding
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background The blood-based biomarkers are approaching the clinical practice of Alzheimer’s disease (AD). Chronic kidney disease (CKD) has a potential confounding effect on peripheral protein levels. It is essential to characterize the impa
Externí odkaz:
https://doaj.org/article/eef79e8a538d4903a66ed6f9e9c8ab03
Publikováno v:
Aging and Health Research, Vol 4, Iss 1, Pp 100182- (2024)
Background: Evidence for the time trend of mortality with dementia from low- and middle-income countries is scarce. Objective: To explore the secular trend of dementia mortality in a Chinese community over 2 decades. Methods: The Shanghai Epidemiolog
Externí odkaz:
https://doaj.org/article/baa501f50d0b4eb8aea9497538e1e446
Autor:
Dongxin Da, Qianhua Zhao, Hao Zhang, Wanqing Wu, Xiaoli Zeng, Xiaoniu Liang, Yiwei Jiang, Zhenxu Xiao, Jin Yu, Saineng Ding, Li Zheng, Ying Zhang, Xiaogang Xu, Ding Ding
Publikováno v:
Journal of Oral Microbiology, Vol 15, Iss 1 (2023)
ABSTRACTThe association between the oral microbiome and mild cognitive impairment (MCI) remains unclear. This study aimed to investigate such an association among Chinese older adults. Participants without dementia were recruited from the community.
Externí odkaz:
https://doaj.org/article/12f158a5253c4863af9ba85387afef5e
Autor:
Zhenxu Xiao, Wanqing Wu, Xiaoxi Ma, Jie Wu, Xiaoniu Liang, Xiaowen Zhou, Yang Cao, Qianhua Zhao, Ding Ding
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract INTRODUCTION Blood biomarkers showed values for predicting future cognitive impairment. Evidence from the community‐based cohort was limited only in high‐income countries. METHODS This study included 1857 dementia‐free community reside
Externí odkaz:
https://doaj.org/article/2afe2d5369ca4fcaa55632c88d62a90d
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract This study aimed to determine whether blood neurofilament light chain (NfL) modifies the association of olfactory dysfunction (OD) with long‐term cognitive decline. A total of 1125 non‐demented older adults in the Shanghai Aging Study we
Externí odkaz:
https://doaj.org/article/a9e7ba70c3bd4da790c928f74f81c9d1
Autor:
Dongxin Da, Suyu Ge, Hao Zhang, Xiaoli Zeng, Yiwei Jiang, Jin Yu, Huning Wang, Wanqing Wu, Zhenxu Xiao, Xiaoniu Liang, Qianhua Zhao, Ding Ding, Ying Zhang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionThe loss of occlusal support due to tooth loss is associated with systemic diseases. However, there was little about the association between occlusal support and cognitive impairment. The cross-sectional study aimed to investigate their a
Externí odkaz:
https://doaj.org/article/8d7d6a12f9164e44bb8d2da6de775072