Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Wanping, Geng"'
Autor:
Ning Li, William L Redmond, Brendan Curti, Shuhang Wang, Herui Yao, Erwei Song, Henry Yu, Giorgio Massimini, Ming-Hong Hu, Rongliang Lou, Wanping Geng, Sanlong Wang, Meiling Zhang, Rongchu Chen, Baotian Qin, John Mao, Shaoshan Wang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/7b531028babd4a6d95e0a4b089285ad9
Autor:
Henry Yu, Hong-Ming Hu, Rongliang Lou, Wanping Geng, Sanlong Wang, William Redmond, Yoshinobu Koguchi, Baotian Qin, John Mao, Shaoshan Wang
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c11132ab706e0188ab3dd3681735e734
https://doi.org/10.1136/jitc-2022-sitc2022.1171
https://doi.org/10.1136/jitc-2022-sitc2022.1171
Autor:
Wanping Geng, Christian Wichmann, Yit Wooi Goh, Angela Rigopoulos, Diana Cao, Linghui Li, Hui K Gan, Yan Lan, Nhi Huynh, Fiona Scott, Andrew M. Scott, Alexander Franklin McDonald, Anup Zutshi, Zhanqi Liu, Sylvia J. Gong, Nancy Guo, Uwe Ackermann, Ingrid Burvenich, Graeme O'Keefe
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 48:3075-3088
Τhis study aimed to optimize the 89Zr-radiolabelling of bintrafusp alfa investigational drug product and controls, and perform the in vitro and in vivo characterization of 89Zr-Df-bintrafusp alfa and 89Zr-Df-control radioconjugates. Bintrafusp alfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b05231523021590b3963635bb631ad8
https://doi.org/10.1007/s00259-021-05251-0
https://doi.org/10.1007/s00259-021-05251-0
Autor:
Yongjun Xue, Glen Hawthorne, Wanping Geng, James Vergis, Andrew P Mayer, Jonathan Wang, Christopher A. James, Lucas Westcott-Baker, Yvonne Katterle, Martin Paton, Jorge Quiroz, Julian Potter, Stephen Keller, Wenkui Li, Dave Christopher, Enaksha R Wickremsinhe, Eric Woolf, Guowen Liu, Joseph Pav
Publikováno v:
Bioanalysis. 13(3)
The use of quality control (QC) samples in bioanalysis is well established and consistent with regulatory guidance. However, a systematic evaluation of whether QC samples serve the intended purpose of improving data quality has not been undertaken. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e33250ce5da0134956c79ddf1a7c3a
https://pubmed.ncbi.nlm.nih.gov/33538614
https://pubmed.ncbi.nlm.nih.gov/33538614
Autor:
Ingrid Julienne Georgette, Burvenich, Yit Wooi, Goh, Nancy, Guo, Hui Kong, Gan, Angela, Rigopoulos, Diana, Cao, Zhanqi, Liu, Uwe, Ackermann, Christian Werner, Wichmann, Alexander Franklin, McDonald, Nhi, Huynh, Graeme Joseph, O'Keefe, Sylvia Jie, Gong, Fiona Elizabeth, Scott, Linghui, Li, Wanping, Geng, Anup, Zutshi, Yan, Lan, Andrew Mark, Scott
Publikováno v:
European journal of nuclear medicine and molecular imaging. 48(10)
Τhis study aimed to optimize theBintrafusp alfa (anti-PD-L1 human IgG1 antibody fused to TGF-β receptor II (TGF-βRII), avelumab (anti-PD-L1 human IgG1 control antibody), isotype control (mutated inactive anti-PD-L1 IgG1 control antibody), and trap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa1fe6362e079eb1d56756ea2c08ef25
https://pubmed.ncbi.nlm.nih.gov/33608805
https://pubmed.ncbi.nlm.nih.gov/33608805
Autor:
Heidi J. Einolf, Susanna Tse, Tonika Bohnert, Sirimas Sudsakorn, Ying-Hong Wang, David Moore, Jim Keirns, Ling He, Robert L. Walsky, Rangaraj Narayanan, Wanping Geng, Aarti Patel, Louis Leung, W. George Lai, Xiaoqing Yang, Ralph Stearns, Dieter Lang, Michael Sinz, Yuan Chen, Chuang Lu, Jan Wahlstrom, Ian Templeton
Publikováno v:
Drug Metabolism and Disposition. 44:1399-1423
Under the guidance of the International Consortium for Innovation and Quality in Pharmaceutical Development (IQ), scientists from 20 pharmaceutical companies formed a Victim Drug-Drug Interactions Working Group. This working group has conducted a rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ff752216b7095cfbd939b67f0dd8ae
https://doi.org/10.1124/dmd.115.069096
https://doi.org/10.1124/dmd.115.069096
Autor:
Robert Francis Kester, Linda Marcus, Marek M. Kabat, Lida Qi, Wang Ka, Michael Pignatello, Wendy Lea Corbett, Cheryl Spence, Franz M. Matschinsky, Lisa M. Garofalo, Roumen Nikolaev Radinov, Ramakanth Sarabu, David J Moore, Yi Ren, Nancy-Ellen Haynes, Zhenmin Liang, Fred Thomas Bizzarro, Darryl W. Hilliard, John Tengi, Wanping Geng, Stanley D. Hutchings, Thomas G. Steele, Joseph Grimsby, Mark T. Dvorozniak, Joseph F. Grippo, Kevin Richard Guertin, Paige Erin Mahaney, Jagdish Kumar Racha
Publikováno v:
Journal of Medicinal Chemistry. 55:7021-7036
Glucokinase (GK) activation as a potential strategy to treat type 2 diabetes (T2D) is well recognized. Compound 1, a glucokinase activator (GKA) lead that we have previously disclosed, caused reversible hepatic lipidosis in repeat-dose toxicology stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aaa5f9f792871c6acf6b9f50fdaa356
https://doi.org/10.1021/jm3008689
https://doi.org/10.1021/jm3008689
Autor:
Wanping Geng, Gopakumar Gopalakrishnan, Michael E. Dunn, Denise Coluccio, Lucette Doessegger, Gerard Hirkaler, Igor Mikaelian, Tanja S. Zabka, Brett H. Saladino, Thomas Singer, Rosemary Nicklaus, Steven E. Lipshultz
Publikováno v:
Toxicologic Pathology. 40:647-650
Myocardial mononuclear cell infiltrate is a spontaneous cardiac finding commonly identified in laboratory cynomolgus monkeys. The infiltrates are predominantly composed of macrophages with lesser lymphocytes and are not typically associated with hist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf4ec99b3739521c0f21ef18ca59425
https://doi.org/10.1177/0192623311436176
https://doi.org/10.1177/0192623311436176
Autor:
Rosemary Nicklaus, Denise Coluccio, Wanping Geng, Igor Mikaelian, Gerard Hirkaler, Lucette Doessegger, Michael E. Dunn, Steven E. Lipshultz, Micaela B. Reddy, Thomas Singer
Publikováno v:
Toxicological Sciences. 123:368-373
Recent improvements in assays have allowed serum cardiac troponin I (cTnI) to be measured at previously undetectable concentrations, which may have implications for cardiotoxicity studies. We characterized the pharmacokinetics of cTnI after a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8380b26a013ba41f88d8418f38be6e5f
https://doi.org/10.1093/toxsci/kfr190
https://doi.org/10.1093/toxsci/kfr190
Autor:
T. Visalli, R. Fernandes, L. Suter Dick, Jean-Christophe Hoflack, Holly Hilton, Michael E. Dunn, Wanping Geng, Denise Coluccio, Andreas Buness, B.W. Boyle, Rosemary Nicklaus, Igor Mikaelian, M. Giron, Gerard Hirkaler, Windy Berkofsky-Fessler, Charu Kanwal, Martin Sanders, Thomas Singer, M.O. Bachynsky
Publikováno v:
Toxicology Letters. 201:110-115
Rosiglitazone, a peroxisome proliferator-activated receptor γ (PPARγ) agonist of the thiazolidinedione class, is a major insulin-sensitizing drug widely used to treat type-2 diabetes. Rosiglitazone causes myocardial hypertrophy in rodents and incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03273ab49fccd31a2e1580982437785f
https://doi.org/10.1016/j.toxlet.2010.12.012
https://doi.org/10.1016/j.toxlet.2010.12.012