Výsledky vyhledávání - "Wanphiwat Chintrakulchai"

Akademický článek

Fine tuning of the net charge alternation of polyzwitterion surfaced lipid nanoparticles to enhance cellular uptake and membrane fusion potential

Autor: Keitaro Homma, Yutaka Miura, Motoaki Kobayashi, Wanphiwat Chintrakulchai, Masahiro Toyoda, Koichi Ogi, Junya Michinishi, Tomoyuki Ohtake, Yuto Honda, Takahiro Nomoto, Hiroyasu Takemoto, Nobuhiro Nishiyama

Publikováno v: Science and Technology of Advanced Materials, Vol 25, Iss 1 (2024)

ABSTRACTLipid nanoparticles (LNPs) coated with functional and biocompatible polymers have been widely used as carriers to deliver oligonucleotide and messenger RNA therapeutics to treat diseases. Poly(ethylene glycol) (PEG) is a representative materi

Externí odkaz: https://doaj.org/article/7f4de8771a724634a58888107d32e430

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Cancerous pH‐responsive polycarboxybetaine‐coated lipid nanoparticle for smart delivery of siRNA against subcutaneous tumor model in mice

Autor: Yi‐Jung Sung, Haochen Guo, Aria Ghasemizadeh, Xin Shen, Wanphiwat Chintrakulchai, Motoaki Kobayashi, Masahiro Toyoda, Koichi Ogi, Junya Michinishi, Tomoyuki Ohtake, Makoto Matsui, Yuto Honda, Takahiro Nomoto, Hiroyasu Takemoto, Yutaka Miura, Nobuhiro Nishiyama

Publikováno v: Cancer Science. 113:4339-4349

Lipid nanoparticles (LNPs) have been commonly used as a vehicle for nucleic acids, such as small interfering RNA (siRNA); the surface modification of LNPs is one of the determinants of their delivery efficiency especially in systemic administration.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8152e97a71a4798962357217e5a3e964
https://doi.org/10.1111/cas.15554

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