Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Wannaporn E. Boonseng"'
Autor:
Miguel Rivera, Mary E. Awad, Wannaporn E. Boonseng, Nicolo Riggi, Scott L. Pomeroy, James Kim, Nikki E. Rossetti, Shruthi Rengarajan, Beverly Naigles, Pablo Tamayo, Gaylor Boulay, Sowmya Iyer, Martin J. Aryee, Jill P. Mesirov, Tenley C. Archer, Angela Volorio
Publikováno v:
Cancer discovery, vol 7, iss 3
Cancer discovery
Cancer discovery
Medulloblastoma is the most frequent malignant pediatric brain tumor and is divided into at least four subgroups known as WNT, SHH, Group 3, and Group 4. Here, we characterized gene regulation mechanisms in the most aggressive subtype, Group 3 tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d08a8335197dcf26a56cda405cf9bcb6
https://escholarship.org/uc/item/1w17q5sn
https://escholarship.org/uc/item/1w17q5sn
Autor:
Nicolo Riggi, Anoop P. Patel, Martin J. Aryee, Vishal Thapar, Gaylor Boulay, Aurélie Formey, G. Petur Nielsen, Ivan Stamenkovic, Shawn M. Gillespie, Edward B. Cook, Nikki E. Rossetti, Melissa Gymrek, Mario L. Suvà, Birgit Knoechel, David T. Ting, Francis J. Hornicek, Bradley E. Bernstein, Esther Rheinbay, Vikram Deshpande, Wannaporn E. Boonseng, Ozgur Oksuz, Miguel Rivera
Publikováno v:
Cancer cell, vol. 26, no. 5, pp. 668-681
SummaryThe aberrant transcription factor EWS-FLI1 drives Ewing sarcoma, but its molecular function is not completely understood. We find that EWS-FLI1 reprograms gene regulatory circuits in Ewing sarcoma by directly inducing or repressing enhancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27644e8c251df925d6e8729c03419ab
https://europepmc.org/articles/PMC4492343/
https://europepmc.org/articles/PMC4492343/