Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Wanli Smith"'
Autor:
Heng Huang, Lishan Lin, Tengteng Wu, Cheng Wu, Leping Zhou, Ge Li, Fengjuan Su, Fengyin Liang, Wenyuan Guo, Weineng Chen, Qiuhong Jiang, Yalun Guan, Xuejiao Li, Pingyi Xu, Yu Zhang, Wanli Smith, Zhong Pei
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Aquaporin-4 (AQP4) is essential for normal functioning of the brain’s glymphatic system. Impaired glymphatic function is associated with neuroinflammation. Recent clinical evidence suggests the involvement of glymphatic dysfunction in LRRK
Externí odkaz:
https://doaj.org/article/101cf4181b6947c9af12f66d347edaec
Autor:
Frederick C. Nucifora, Leslie G. Nucifora, Chee-Hoe Ng, Nicolas Arbez, Yajuan Guo, Elaine Roby, Vered Shani, Simone Engelender, Dong Wei, Xiao-Fang Wang, Tianxia Li, Darren J. Moore, Olga Pletnikova, Juan C. Troncoso, Akira Sawa, Ted M. Dawson, Wanli Smith, Kah-Leong Lim, Christopher A. Ross
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Mutations in LRRK2 are linked to Parkinson’s Disease. Here, the authors identify WSB1 as a LRRK2 interacting protein and find that it promotes LRRK2 aggregation in primary neurons and drosophila models via ubiquitin K27 and K29 linkages.
Externí odkaz:
https://doaj.org/article/0422154ec8e94aaeacb24bc6f49b8afd
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61013 (2013)
The effects of pyrroloquinoline quinine (PQQ) on RANKL-induced osteoclast differentiation and on wear particle-induced osteolysis were examined in this study. PQQ inhibited RANKL-mediated osteoclast differentiation in bone marrow macrophages (BMMs) i
Externí odkaz:
https://doaj.org/article/2058a82a46384f94b7385d3dcb6848a2
Autor:
Yi Huang, Heng Huang, Leping Zhou, Jiawei Li, Xiang Chen, Joseph Thomas, Xiaofei He, Wenyuan Guo, Yixuan Zeng, Boon Chuan Low, Fengyin Liang, Jinsheng Zeng, Christopher A Ross, Eng-King Tan, Wanli Smith, Zhong Pei
Publikováno v:
Human molecular genetics. 31(22)
The D620N mutation in vacuolar protein sorting protein 35 (VPS35) gene has been identified to be linked to late onset familial Parkinson disease (PD). However, the pathophysiological roles of VPS35-D620N in PD remain unclear. Here, we generated the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88c285ea1be8534d33278f5cdc72651
https://pubmed.ncbi.nlm.nih.gov/35766879
https://pubmed.ncbi.nlm.nih.gov/35766879
Publikováno v:
Bioscience Reports; Jul2020, Vol. 40 Issue 7, p1-10, 10p