Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Wankyu, Kim"'
Autor:
Jihee Kim, Gina Ryu, Jeongmin Seo, Miyeon Go, Gyungmin Kim, Sol Yi, Suwon Kim, Hana Lee, June-Yong Lee, Han Sung Kim, Min-Chan Park, Dong Hae Shin, Hyunbo Shim, Wankyu Kim, Soo Young Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Osteoarthritis (OA) is a progressive and irreversible degenerative joint disease that is characterized by cartilage destruction, osteophyte formation, subchondral bone remodeling, and synovitis. Despite affecting millions of patients, effect
Externí odkaz:
https://doaj.org/article/aaecf392acf84674abcd7e5c83bc4ee4
Autor:
Ju Hee Oh, Dae Won Jun, Hye Young Kim, Seung Min Lee, Eileen L. Yoon, Jungwook Hwang, Jung Hwan Park, Hanbi Lee, Wankyu Kim, Hyunsung Kim
Publikováno v:
Clinical and Molecular Hepatology, Vol 28, Iss 3, Pp 497-509 (2022)
Background/Aims We aimed to define an optimal target population and drug-specific biomarkers that may predict dipeptidyl peptidase (DPP)-4 inhibitor responses in non-alcoholic fatty liver disease (NAFLD). Methods An exploration study (study I) was pe
Externí odkaz:
https://doaj.org/article/df6858c4f9f14c0781d449633c22ed0d
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 35, Iss , Pp 100862- (2023)
Intrinsic or acquired radioresistance often limits the efficacy of radiation therapy (RT), thereby leading to local control failure. Cancerous cells have abnormal pH dynamics due to high metabolic demands, but it is unclear how pH dynamics contribute
Externí odkaz:
https://doaj.org/article/417343b4bec84bda8ffa875369fd7d4a
Autor:
Doo Ri Park, Jihee Kim, Gyeong Min Kim, Haeseung Lee, Minhee Kim, Donghyun Hwang, Hana Lee, Han-Sung Kim, Wankyu Kim, Min Chan Park, Hyunbo Shim, Soo Young Lee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Osteoarthritis (OA) is associated with cartilage disruption, but the underlying mechanisms remain unclear. Here, the authors show that expression of osteoclast-associated receptor (OSCAR) is associated with OA, that its genetic ablation or targeting
Externí odkaz:
https://doaj.org/article/5de8b89375a3490286669ccd5365ba62
Publikováno v:
Journal of Cheminformatics, Vol 11, Iss 1, Pp 1-8 (2019)
Abstract Drug discovery typically involves investigation of a set of compounds (e.g. drug screening hits) in terms of target, disease, and bioactivity. CSgator is a comprehensive analytic tool for set-wise interpretation of compounds. It has two uniq
Externí odkaz:
https://doaj.org/article/974589fb30194edab7d88dde51cd597f
Publikováno v:
Journal of Chemical Information and Modeling. 63:1429-1437
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c9cc33d7eb1acc29bdc6f11cd2ceafa
https://doi.org/10.1021/acs.jcim.2c01300
https://doi.org/10.1021/acs.jcim.2c01300
Autor:
Ok-Seon Kwon, Eun-Ji Kwon, Hyeon-Joon Kong, Jeong-Yoon Choi, Yun-Jeong Kim, Eun-Woo Lee, Wankyu Kim, Haeseung Lee, Hyuk-Jin Cha
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101719- (2020)
Erastin, a synthetic lethal compound against cancer expressing an oncogenic RAS, inhibits cystine/glutamate antiporters and causes ferroptosis. However, despite recent evidence for the mechanisms underlying ferroptosis, molecular biomarkers of erasti
Externí odkaz:
https://doaj.org/article/9f43a3232f5943e0bce94ef45fafad38
Autor:
Soon-Ki Hong, Haeseung Lee, Ok-Seon Kwon, Na-Young Song, Hyo-Ju Lee, Seungmin Kang, Jeong-Hwan Kim, Mirang Kim, Wankyu Kim, Hyuk-Jin Cha
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-7 (2018)
Abstract Even when targets responsible for chemoresistance are identified, drug development is often hampered due to the poor druggability of these proteins. We systematically analyzed therapy-resistance with a large-scale cancer cell transcriptome a
Externí odkaz:
https://doaj.org/article/fe9f31f955e54799840c26ecbf0213d0
Autor:
Seung-Ju Cho, Keun-Tae Kim, Ho-Chang Jeong, Ju-Chan Park, Ok-Seon Kwon, Yun-Ho Song, Joong-Gon Shin, Seungmin Kang, Wankyu Kim, Hyoung Doo Shin, Mi-Ok Lee, Sung-Hwan Moon, Hyuk-Jin Cha
Publikováno v:
Stem Cell Reports, Vol 11, Iss 5, Pp 1244-1256 (2018)
Summary: The selective survival advantage of culture-adapted human embryonic stem cells (hESCs) is a serious safety concern for their clinical application. With a set of hESCs with various passage numbers, we observed that a subpopulation of hESCs at
Externí odkaz:
https://doaj.org/article/592605e5a71c47feab63b767afa74cf0
Autor:
Jae Seok Jeong, Jin Young Choi, Jong Seung Kim, Seong Ok Park, Wankyu Kim, Yeo‐Gha Yoon, Hae Jin Park, Kyung Hwa Park, Doo Hwan Kim, Jung Mo Kim, Gou Young Koh, Seong Kug Eo, Yong Chul Lee
Publikováno v:
Allergy. 78:287-290
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c47a0a336f301adb512a9aaab799cd
https://doi.org/10.1111/all.15452
https://doi.org/10.1111/all.15452