Výsledky vyhledávání - "Wania Renata Santos"

Immunotherapy against murine experimental visceral leishmaniasis with the FML-vaccine

Autor: Valéria Marçal Felix de Lima, Wania Renata Santos, Clarisa B. Palatnik-de-Sousa, Marcos Palatnik, Edilma Paraguai de Souza, Ivan Augusto Aguiar

Publikováno v: Vaccine. 21:4668-4676

The fucose mannose ligand (Leishmania donovani FML)-saponin vaccine has earlier shown its immunoprophylactic potential against visceral leishmaniasis in the CB hamster (87.7% of parasite load reduction), Balb/c (84.4%) and Swiss albino mouse (85–93

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c64fe351017927dccd5dfc3fd0b380b
https://doi.org/10.1016/s0264-410x(03)00527-9

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Saponins, IL12 and BCG adjuvant in the FML-vaccine formulation against murine visceral leishmaniasis

Autor: Clarisa Beatriz Palatnik de Sousa, Edilma Paraguai de Souza, Robson R. Bernardo, Valéria Marçal Felix de Lima, Wania Renata Santos, Marcos Palatnik

Publikováno v: Vaccine. 21:30-43

The FML antigen of Leishmania donovani, in combination with either Riedel de Haen (R), QuilA, QS21 saponins, IL12 or BCG, was used in vaccination of an outbred murine model against visceral leishmaniasis (VL). Significant and specific increases in an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3f5d1e6f071decf53350837332afbd
https://doi.org/10.1016/s0264-410x(02)00444-9

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Long lasting protection against canine kala-azar using the FML-QuilA saponin vaccine in an endemic area of Brazil (S�o Gon�alo do Amarante, RN)

Autor: Elza M. Gomes, Kleber Giovanni Luz, V. O. da Silva, Marcos Palatnik, G.P. Borja-Cabrera, N N Correia Pontes, E Paraguai de Souza, C.B. Palatnik de Sousa, Wania Renata Santos

Publikováno v: Vaccine. 20:3277-3284

Naturally exposed dogs of an endemic area were vaccinated with the fucose mannose ligand (FML) antigen of Leishmania donovani in formulation with QuilA saponin. The 100% of vaccinees were seropositive to FML and showed intradermal reaction to L. dono

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c971456034afb10aafd39ab1e2fb726f
https://doi.org/10.1016/s0264-410x(02)00294-3

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Protective vaccination against murine visceral leishmaniasis using aldehyde-containing Quillaja saponaria sapogenins

Autor: J. P. Parente, B.P. da Silva, E Paraguai de Souza, C.B. Palatnik de Sousa, C.P. Casas, Marcos Palatnik, Luzineide W. Tinoco, Wania Renata Santos

Publikováno v: Vaccine. 22(19)

The presence of aldehyde groups at C-23 and C-24 of the triterpen aglycon moiety was disclosed in 1H NMR spectra of both the Riedel de Haen saponin (R) (delta 9.336) and Quillaja saponaria QuilA saponin (delta 9.348). The sign of the C-28 acylated li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc47f5a3b689b5ee2478c1c410b99852
https://pubmed.ncbi.nlm.nih.gov/15193411

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Vaccination of Swiss Albino mice against experimental visceral leishmaniasis with the FML antigen of Leishmania donovani

Autor: Wania Renata Santos, Marcos Palatnik, Clarisa Beatriz Palatnik de Sousa, Edilma Paraguai de Souza

Publikováno v: Vaccine. 17(20-21)

The FML antigen of Leishmania donovani in combination with saponin, aluminum hydroxide (Al(OH)3) and Freund's incomplete adjuvant (FIA) was used in vaccines tested in an outbred murine model of visceral leishmaniasis, either through intraperitoneal o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d20988c264ff89be42cf4f67989741
https://pubmed.ncbi.nlm.nih.gov/10418902

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Haemolytic activities of plant saponins and adjuvants. Effect of Periandra mediterranea saponin on the humoral response to the FML antigen of Leishmania donovani

Autor: Clarisa Beatriz Palatnik de Sousa, J. P. Parente, Wania Renata Santos, Marcos Palatnik, Ligia M.T. Peçanha, Robson R. Bernardo

Publikováno v: Vaccine. 15(9)

An 87.7% (P0.01) and 84% (P0.001) of protection against visceral leishmaniasis was achieved in CB hamsters and Balb/c mice, respectively, with saponin combined to the fucose-mannose ligand of Leishmania donovani (FML). However, an undesirable haemoly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becade8771fe87ffa6dffcc5058deb78
https://pubmed.ncbi.nlm.nih.gov/9261952

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The FML (Fucose Mannose Ligand) of Leishmania donovani: a new tool in diagnosis, prognosis, transfusional control and vaccination against human kala-azar

Autor: Kleber Luz, Linnete V. de Medeiros, Edilma Paraguai de Souza, Elza M. Gomes, Sirley R. de Macedo, Claris B. Palatnik de Sousa, Wania Renata Santos

Publikováno v: Revista da Sociedade Brasileira de Medicina Tropical v.29 n.2 1996
Revista da Sociedade Brasileira de Medicina Tropical
Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
Revista da Sociedade Brasileira de Medicina Tropical, Vol 29, Iss 2, Pp 153-163 (1996)
Revista da Sociedade Brasileira de Medicina Tropical, Volume: 29, Issue: 2, Pages: 153-163, Published: APR 1996

The Fucose-Mannose Ligand (FML) of Leishmania donovani is a complex glycoproteic fraction. Its potential use as a tool for diagnosis of human visceral leishmaniasis was tested with human sera from Natal, Rio Grande do Norte, Brazil. The FML-ELISA tes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d3f3c28c52d7f39d6b5983f18c26cb
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821996000200008

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