Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Wanhui Lin"'
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Epilepsy is a chronic neurological disorder characterized by recurrent seizures that significantly impact patients’ quality of life. Identifying predictors is crucial for early intervention. Objective: Electroencephalography (EEG) micro
Externí odkaz:
https://doaj.org/article/1b8842cd2cb94d06ace7ea1a3ea66b5a
Autor:
Xiangyi Wang, Wenting Xiong, Man Li, Luyan Wu, Yuying Zhang, Chaofeng Zhu, Wanhui Lin, Shenggen Chen, Huapin Huang
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundEpilepsy is one of the most prevalent serious brain disorders globally, impacting over 70 million individuals. Observational studies have increasingly recognized the impact of plasma lipidome on epilepsy. However, establishing a direct caus
Externí odkaz:
https://doaj.org/article/2beab3151a2b49beaa3627599f2cf719
Autor:
Mingxing Lin, Jiayin Gong, Luyan Wu, Xin Lin, Yuying Zhang, Wanhui Lin, Huapin Huang, Chaofeng Zhu
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
ObjectiveEpilepsy is a common neurological disorder characterized by recurrent epilepsy episodes. As a non-pharmacological treatment, the ketogenic diet has been widely applied in treating epilepsy. However, the exact therapeutic mechanism of the ket
Externí odkaz:
https://doaj.org/article/987e73f4460a458aaecd4df661bada96
Publikováno v:
Stem Cell Research, Vol 74, Iss , Pp 103268- (2024)
The human iPS cell line, hiPS-RTT (FJMUi002-A), is derived from peripheral blood mononuclear cells (PBMCs) from a 12-year-old female RTT patient carrying a heterozygous p. R133C (c.397C > T) mutation in the MeCP2 gene. The hiPS-RTT cell line was gene
Externí odkaz:
https://doaj.org/article/0c4f0d0ca0e54f2a9460a8f8639e1b7b
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Drug-resistant epilepsy (DRE) patients exhibit aberrant large-scale brain networks. Perampanel may be a therapeutic option for controlling seizures in these patients. Objective: We aim to explore the differences of resting-state electroen
Externí odkaz:
https://doaj.org/article/adce7184200c4176ab9756ffd6f9532d
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveThe objective of this study was to identify the factors that affect the efficacy of added perampanel for the treatment of drug-resistant epilepsy (DRE), and to develop a reliable nomogram to predict the benefit of this addition.MethodsA retr
Externí odkaz:
https://doaj.org/article/ea968423d13742c6af4dcfabf4ee9876
Autor:
Feng Lin, Jiarui Han, Teng Xue, Jilan Lin, Shenggen Chen, Chaofeng Zhu, Han Lin, Xianyang Chen, Wanhui Lin, Huapin Huang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Many studies report predictions for cognitive function but there are few predictions in epileptic patients; therefore, we established a workflow to efficiently predict outcomes of both the Mini-Mental State Examination (MMSE) and Montreal Co
Externí odkaz:
https://doaj.org/article/d06ade1ce43f4535aa529274a46757e4
Autor:
Feng Lin, Wanhui Lin, Chaofeng Zhu, Jilan Lin, Junge Zhu, Xu-Ying Li, Zhanjun Wang, Chaodong Wang, Huapin Huang
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with neuronal cell inclusions composed of neurofilaments and other abnormal aggregative proteins as pathological hallmarks. Approximately 90% of patien
Externí odkaz:
https://doaj.org/article/cd0b5198e3b1446ca8569dc63bcc28d2
Publikováno v:
Acta Epileptologica, Vol 2, Iss 1, Pp 1-8 (2020)
Abstract Background Electroencephalogram (EEG) is an important tool for the diagnosis of herpes simplex virus encephalitis (HSE). However, the diagnosis of non-convulsive status epilepticus (NCSE) in HSE is challenging without the help of continuous
Externí odkaz:
https://doaj.org/article/03e1a2a2a45b4bd997f622a4fbb822f7
Autor:
Chaofeng Zhu, Rong Lin, Changyun Liu, Mingzhu Huang, Feng Lin, Gan Zhang, Yuying Zhang, Junjie Miao, Wanhui Lin, Huapin Huang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Recent studies have documented that reduced M-current promotes epileptogenesis and attenuates synaptic remodeling. Neurite growth is closely related to the level of 5-HT6 receptor (5-HT6R) in the central nervous system. However, little research is av
Externí odkaz:
https://doaj.org/article/3224867a974f4d27a797c98cbb20aba5