Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Wangzhong CHEN"'
Publikováno v:
Iranian Journal of Public Health, Vol 45, Iss 10, Pp 1371-1372 (2016)
No Abstract
Externí odkaz:
https://doaj.org/article/7636a3400b1a48e98ebd71d2b9cc7ffc
Autor:
Wangzhong Chen, Kenneth A. Jacobson, Lak Shin Jeong, Bhalchandra V. Joshi, Yong-Chul Kim, Ga Eun Lee, Hyung Ryong Moon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:571-575
Analogues of the P2X 7 receptor antagonist KN-62, modified at the piperazine and arylsulfonyl groups, were synthesized and assayed at the human P2X 7 receptor for inhibition of BzATP-induced effects, that is, uptake of a fluorescent dye (ethidium bro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712e31984d420354027fd3dc3dac1559
https://doi.org/10.1016/j.bmcl.2007.11.077
https://doi.org/10.1016/j.bmcl.2007.11.077
Autor:
Wangzhong Chen, Kenneth A. Jacobson, Hak Sung Kim, Kyeong Lee, Aishe Chen, Soo-Kyung Kim, Zhan-Guo Gao, Bruce T. Liang, Gnana Ravi, Dov Barak, Seong Gon Kim
Publikováno v:
Drug Dev Res
Modification of the ribose moiety of nucleotides and nucleosides has provided new insights into structural and conformational requirements for ligands at P2Y nucleotide receptors and at adenosine receptors (ARs). Methanocarba derivatives (containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9372b350d350708a7f60a45b0ef9de73
https://doi.org/10.1002/ddr.10168
https://doi.org/10.1002/ddr.10168
Publikováno v:
Journal of Biological Chemistry. 277:46622-46631
We investigated the role of the eight acidic residues in the extracellular loops (exo-loops) of the seven-transmembrane domain of the human Ca(2+) receptor (hCaR) in receptor activation by Ca(2+) and in response to a positive allosteric modulator, NP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff9b608ee92612df80890d76b4e75a5
https://doi.org/10.1074/jbc.m207100200
https://doi.org/10.1074/jbc.m207100200
Autor:
Kyeong Lee, Zhan-Guo Gao, Carl R. Johnson, Thibaud Biadatti, Kenneth A. Jacobson, Wangzhong Chen, Soo-Kyung Kim, Dov Barak, Seong Gon Kim
Publikováno v:
J Med Chem
Mutagenesis of the human A(3) adenosine receptor (AR) suggested that certain amino acid residues contributed differently to ligand binding and activation processes. Here we demonstrated that various adenosine modifications, including adenine substitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b16f5a319ee67dc8829b5f0e2c1ee87
https://doi.org/10.1021/jm020211+
https://doi.org/10.1021/jm020211+
Publikováno v:
Bioconjugate chemistry. 13(5)
Chemically funtionalized analogues of antagonists of the P2X(7) receptor, an ATP-gated cation channel, were synthesized as tools for biophysical studies of the receptor. These functionalized congeners were intended for use in chemical conjugation wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cccf9a048a9730fe78d744cbb9f63c
https://pubmed.ncbi.nlm.nih.gov/12236792
https://pubmed.ncbi.nlm.nih.gov/12236792
Autor:
Yong-Chul Kim, Kenneth A. Jacobson, Lak Shin Jeong, Ga Eun Lee, Wangzhong Chen, Hyung Ryong Moon, Bhalchandra V. Joshi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:556
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::563cdb49372d373643f0868869e7fc7b
https://doi.org/10.1016/j.bmcl.2008.05.108
https://doi.org/10.1016/j.bmcl.2008.05.108
Autor:
Kenneth A. Jacobson, Hak Sung Kim, Gnana Ravi, Soo-Kyung Kim, Kyeong Lee, Aishe Chen, Wangzhong Chen, Seong Gon Kim, Dov Barak, Bruce T. Liang, Zhan-Guo Gao
Publikováno v:
Drug Development Research; Apr2003, Vol. 58 Issue 4, p330-339, 10p