Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Wangyong Shin"'
Autor:
Ryeonghwa Kang, Kyungdeok Kim, Yewon Jung, Sang-Han Choi, Chanhee Lee, Geun Ho Im, Miram Shin, Kwangmin Ryu, Subin Choi, Esther Yang, Wangyong Shin, Seungjoon Lee, Suho Lee, Zachary Papadopoulos, Ji Hoon Ahn, Gou Young Koh, Jonathan Kipnis, Hyojin Kang, Hyun Kim, Won-Ki Cho, Soochul Park, Seong-Gi Kim, Eunjoon Kim
Publikováno v:
PLoS Biology, Vol 22, Iss 5, p e3002596 (2024)
Autism spectrum disorders (ASD) frequently accompany macrocephaly, which often involves hydrocephalic enlargement of brain ventricles. Katnal2 is a microtubule-regulatory protein strongly linked to ASD, but it remains unclear whether Katnal2 knockout
Externí odkaz:
https://doaj.org/article/5c97fd7bf8714d0980f93431d5b5bc26
Autor:
Hyo Jae Kim, Jong-Eun Park, Wangyong Shin, Dayoung Seo, Seungmi Kim, Hyunji Kim, Jinsung Noh, Yonghee Lee, Hyunjin Kim, Young-Min Lim, Hyori Kim, Eun-Jae Lee
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Background Neuromyelitis optica spectrum disorder (NMOSD) stands out among CNS inflammatory demyelinating diseases (CIDDs) due to its unique disease characteristics, including severe clinical attacks with extensive lesions and its associatio
Externí odkaz:
https://doaj.org/article/ca4ebcd0c418437d8b9c84dbde31178a
Autor:
Lynkyung Choi, Wangyong Shin, Seungmi Kim, Hyunji Kim, Dayoung Seo, Seungjoon Lee, Hyojin Kang, Jae-Hong Lee, Sungyang Jo, Seungjoo Lee, Seung-Yong Yoon, Eun-Jae Lee, Eunjoon Kim
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S385-S386 (2023)
Externí odkaz:
https://doaj.org/article/d90f16774b9e48f2bbb3d8da5d979007
Autor:
Yoon Ok Jang, Hee-Sung Ahn, Thuy Nguyen Thi Dao, JeongYeon Hong, Wangyong Shin, Young-Min Lim, Sun Ju Chung, Jae-Hong Lee, Huifang Liu, Bonhan Koo, Myoung Gyu Kim, Kyunggon Kim, Eun-Jae Lee, Yong Shin
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-19 (2023)
Abstract Background Brain-derived exosomes released into the blood are considered a liquid biopsy to investigate the pathophysiological state, reflecting the aberrant heterogeneous pathways of pathological progression of the brain in neurological dis
Externí odkaz:
https://doaj.org/article/37ee104125cd41f198807336f876c788
Autor:
Eunkyung Lie, Yeji Yeo, Eun-Jae Lee, Wangyong Shin, Kyungdeok Kim, Kyung Ah Han, Esther Yang, Tae-Yong Choi, Mihyun Bae, Suho Lee, Seung Min Um, Se-Young Choi, Hyun Kim, Jaewon Ko, Eunjoon Kim
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
To elucidate the role of synaptic cell adhesion-like molecule 4 (SALM4) in altering synaptic function in the context of fear memory, Lie at al performed behavioural and electrophysiological assessments of SALM4 knockout mice undergoing cued fear, spa
Externí odkaz:
https://doaj.org/article/9c6821f43b5b415bb8a595e34ac8759f
Autor:
Sun-Gyun Kim, Suho Lee, Yangsik Kim, Jieun Park, Doyeon Woo, Dayeon Kim, Yan Li, Wangyong Shin, Hyunjeong Kang, Chaehyun Yook, Minji Lee, Kyungdeok Kim, Junyeop Daniel Roh, Jeseung Ryu, Hwajin Jung, Seung Min Um, Esther Yang, Hyun Kim, Jinju Han, Won Do Heo, Eunjoon Kim
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Alterations of the mTOR signalling pathway are associated with neurodevelopmental defects. Regulators of the mTOR kinase activity are not fully described. Here, the authors show that Tanc2, a scaffolding protein, acts as a direct inhibitor of mTOR ki
Externí odkaz:
https://doaj.org/article/2112da6461bf4b75bab1ac9b8695d0c5
Autor:
Sun-Gyun Kim, Suho Lee, Yangsik Kim, Jieun Park, Doyeon Woo, Dayeon Kim, Yan Li, Wangyong Shin, Hyunjeong Kang, Chaehyun Yook, Minji Lee, Kyungdeok Kim, Junyeop Daniel Roh, Jeseung Ryu, Hwajin Jung, Seung Min Um, Esther Yang, Hyun Kim, Jinju Han, Won Do Heo, Eunjoon Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/9ac653fc42424ff69c98a3ec718ba064
Autor:
Wangyong Shin, Kyungdeok Kim, Benjamin Serraz, Yi Sul Cho, Doyoun Kim, Muwon Kang, Eun-Jae Lee, Hyejin Lee, Yong Chul Bae, Pierre Paoletti, Eunjoon Kim
Publikováno v:
PLoS Biology, Vol 18, Iss 4, p e3000717 (2020)
Extensive evidence links Glutamate receptor, ionotropic, NMDA2B (GRIN2B), encoding the GluN2B/NR2B subunit of N-methyl-D-aspartate receptors (NMDARs), with various neurodevelopmental disorders, including autism spectrum disorders (ASDs), but the unde
Externí odkaz:
https://doaj.org/article/9bd6c39272704fa28da91839a3a974d8
Autor:
Kyungdeok Kim, Wangyong Shin, Muwon Kang, Suho Lee, Doyoun Kim, Ryeonghwa Kang, Yewon Jung, Yisul Cho, Esther Yang, Hyun Kim, Yong Chul Bae, Eunjoon Kim
Publikováno v:
eLife, Vol 9 (2020)
Synaptic adhesion molecules regulate synapse development and function. However, whether and how presynaptic adhesion molecules regulate postsynaptic NMDAR function remains largely unclear. Presynaptic LAR family receptor tyrosine phosphatases (LAR-RP
Externí odkaz:
https://doaj.org/article/392bae0356a04a2fb734b61ed90253a8
Autor:
Seung Min Um, Seungmin Ha, Hyejin Lee, Jihye Kim, Kyungdeok Kim, Wangyong Shin, Yi Sul Cho, Junyeop Daniel Roh, Jaeseung Kang, Taesun Yoo, Young Woo Noh, Yeonsoo Choi, Yong Chul Bae, Eunjoon Kim
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3839-3851 (2018)
Summary: Netrin-G ligand 2 (NGL-2)/LRRC4, implicated in autism spectrum disorders and schizophrenia, is a leucine-rich repeat-containing postsynaptic adhesion molecule that interacts intracellularly with the excitatory postsynaptic scaffolding protei
Externí odkaz:
https://doaj.org/article/d9b6e40f58624648aa75469ba139add9