Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Wangteng Wu"'
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Formation of vicinal, quaternary stereocentres is challenging, but such products are commonly encountered in nature. Here, the authors report a palladium catalysed process to form vicinal quaternary carbons via propargylation, including in enantiopur
Externí odkaz:
https://doaj.org/article/b6c82ba35c4b4f7f9e58b8e16e735bde
Autor:
Qida Hu, Shiyi Shao, Tingbo Liang, Wangteng Wu, Meng Wang, Xinyu Zhao, Junming Huang, Guping Tang
Publikováno v:
Biomaterials Science. 8:6579-6591
As one of the most malignant primary cancers, hepatocellular carcinoma (HCC) still lacks an efficient therapeutic strategy to date. Here, we developed a polymer-based nanoplatform PEI-βCD@Ad-CDM-PEG (PCACP) for functional microRNA (miRNA) therapy. P
Autor:
Xinyu Zhao, Yueming Wang, Nan Zhang, Qida Hu, Jiwei Huang, Yichu Yuan, Wangteng Wu, Piaopiao Jin
Publikováno v:
RSC Advances. 10:37826-37833
Purpose: Aiming to improve the drug loading capacity of dendritic nanoparticles and enhance delivery efficacy in drug-resistant cancer, we developed and optimized a more advanced dendritic, redox-responsive, supramolecular (Dr.S) system for intraveno
Publikováno v:
Advanced Synthesis & Catalysis. 361:3228-3233
Autor:
Shiyi Shao, Meng Wang, Guping Tang, Junming Huang, Xinyu Zhao, Tingbo Liang, Qida Hu, Hongzhen Bai, Wangteng Wu
Publikováno v:
Chemical Communications. 55:9363-9366
We developed a biodegradable, oncosensitive, megamer-based delivery system for miRNA therapy. The miRNA nanotherapeutics, activatable by stepwise stimulation of acidity and reduction mimicking tumor microenvironment, efficiently improve liver-specifi
Autor:
Xinyu Zhao, Wangteng Wu, Qihan Fu, Bingfeng Huang, Shiyi Shao, Risheng Que, Qida Hu, Piaopiao Jin
Publikováno v:
Japanese Journal of Clinical Oncology. 48:1058-1069
Background The effectiveness of combination therapy of transarterial chemoembolization and sorafenib for unresectable hepatocellular carcinoma are controversial in some studies. This meta-analysis aims to compare efficacy and safety, as well as regio
Publikováno v:
Nano letters. 20(1)
We herein propose a bioengineering approach where bacterial outer membrane vesicles (OMVs) were coated on drug-loaded polymeric micelles to generate an innovative nanomedicine for effective cancer immunotherapy and metastasis prevention. Whereas OMVs
Autor:
Tingbo Liang, Guping Tang, Shiyi Shao, Jianwei Wang, Xinyu Zhao, Junming Huang, Wangteng Wu, Qi Chen, Qida Hu, Hongzhen Bai, Piaopiao Jin, Meng Wang
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 317
Malignancies treated by insoluble targeted agents show low dose exposure and therapeutic responses, therefore easily develop drug resistance. Nanoparticle-modified drugs might disrupt chemoresistance by increasing dose exposure and altering resistanc
Publikováno v:
World Journal of Gastroenterology
BACKGROUND Liver cancer is the sixth most commonly diagnosed cancer and the fourth leading cause of cancer death worldwide. Socioeconomic development, indicated by the Human Development Index (HDI), is closely interconnected with public health. But t
Publikováno v:
Advanced Synthesis & Catalysis. 358:2791-2805
The palladium-catalyzed tandem reactions of 2,7-alkadiynylic carbonates with 2,3-allenyl sulfamides for the syntheses of fused tricycles such as 1,3,6,7,8,9-hexahydrofuro[3,4-h]isoquinoline, 2,3,6,7,8,9-hexahydro-1H-pyrrolo[3,4-h]isoquinoline, and 2,