Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Wangtao Zhong"'
Autor:
Xiaotang Ma, Yan Wang, Yumeng Shi, Suqing Li, Jinhua Liu, Xiangyong Li, Wangtao Zhong, Qunwen Pan
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background/aims Vascular dementia (VD) results in cognition and memory deficit. Exosomes and their carried microRNAs (miRs) contribute to the neuroprotective effects of mesenchymal stromal cells, and miR-132-3p plays a key role in neuron pla
Externí odkaz:
https://doaj.org/article/7c4e783e80c84653b2492e801ce0049a
Autor:
Zhen Jing, Hao Li, Shengming Huang, Min Guan, Yongxin Li, Kui Lu, Jianzhou Wu, Wangtao Zhong, Li’an Huang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Endovascular treatment (EVT) has been accepted as the standard of care for patients with acute ischemic stroke. The aim of the present study was to compare clinical outcomes of patients who received EVT within and beyond 6 h from symptom ons
Externí odkaz:
https://doaj.org/article/168b59465938416d9530fd554b29ec16
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Pompe disease is an autosomal recessive hereditary lysosomal disorder and correlated with acid α-glucosidase enzyme (GAA) deficiencies, which lead to accumulation of glycogen in all tissues, most notably in skeletal muscles. Adult late-onset Pompe d
Externí odkaz:
https://doaj.org/article/923a5426f24c40c6ae3e7bb25a76824e
Autor:
Hua Tao, Zengqiang Chen, Jianhao Wu, Jun Chen, Yusen Chen, Jiawu Fu, Chaowen Sun, Haihong Zhou, Wangtao Zhong, Xu Zhou, Keshen Li
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Epilepsy is characterized by highly abnormal synchronous discharge of brain neurons, and ion channels are fundamental in the generation and modulation of neural excitability. Considering that abnormal methylation can either activate or repress genes,
Externí odkaz:
https://doaj.org/article/b4be49b3e14e47eabec1c4b3b14a107d
Autor:
Hua Tao, Xu Zhou, Jun Chen, Haihong Zhou, Lidan Huang, Yujie Cai, Jiawu Fu, Zhou Liu, Yanyan Chen, Chaowen Sun, Bin Zhao, Wangtao Zhong, Keshen Li
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Recent studies have reported patients who concurrently exhibit conditions of epilepsy and schizophrenia, indicating certain shared pathologies between them. This study aimed to investigate the genetic effects of the schizophrenia-related gene DTNBP1
Externí odkaz:
https://doaj.org/article/7280ed43a06c4c709b3b2e06cb462080
Publikováno v:
Neural Plasticity, Vol 2020 (2020)
Neurological diseases are a major threat to global public health and prosperity. The number of patients with neurological diseases is increasing due to the population aging and increasing life expectancy. Autophagy is one of the crucial mechanisms to
Externí odkaz:
https://doaj.org/article/497696b8eb8c4913b5fea6421027501e
Autor:
You Li, Linfa Chen, Shaoyu Yao, Jianya Chen, Weidong Hu, Mengxu Wang, Shaofeng Chen, Xinglan Chen, Shengnan Li, Xuefeng Gu, Guoda Ma, Bin Zhao, Wangtao Zhong, Keshen Li
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 6, Pp 2188-2199 (2018)
Background/Aims: Matrix metalloproteinase 9 (MMP9), a potent endopeptidase degrading extracellular matrix, plays a pivotal role in the pathogenesis of ischaemic stroke (IS). The present study was undertaken to determine the association of MMP9 gene p
Externí odkaz:
https://doaj.org/article/19befb25433844478a27466265ec50af
The Regulatory Role of Long Noncoding RNAs in Different Brain Cell Types Involved in Ischemic Stroke
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Stroke results in high morbidity and high mortality worldwide, with ischemic stroke accounting for 80% to 85%. As effective treatments for ischemic stroke remain limited because of the narrow therapeutic time window, a better understanding of the pat
Externí odkaz:
https://doaj.org/article/fb009453fb33418d9acbdc1622911c08
Autor:
Qunwen Pan, Jieyi Zheng, Donghui Du, Xiaorong Liao, Chunlian Ma, Yi Yang, Yanyu Chen, Wangtao Zhong, Xiaotang Ma
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Endothelial progenitor cells (EPCs) have shown the potential for treating ischemic stroke (IS), while microRNA-126 (miR-126) is reported to have beneficial effects on endothelial function and angiogenesis. In this study, we investigated the effects o
Externí odkaz:
https://doaj.org/article/37bbe75baa424905b35578fa6fdce4e2
Autor:
Hua Tao, Jianghao Zhao, Tingting Liu, Yujie Cai, Xu Zhou, Huaijie Xing, Yan Wang, Mingkang Yin, Wangtao Zhong, Zhou Liu, Keshen Li, Bin Zhao, Haihong Zhou, Lili Cui
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Unveiling the key mechanism of temporal lobe epilepsy (TLE) for the development of novel treatments is of increasing interest, and anti-inflammatory miR-146a is now considered a promising molecular target for TLE. In the current study, a C57BL/6 TLE
Externí odkaz:
https://doaj.org/article/200ee5bc4e0345eb91a964154fa2790d