Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Wanglin, Jiang"'
Autor:
Liang Ye, Chunmei Li, Wanglin Jiang, Yifei Yang, Wenyan Wang, Haibo Zhu, Zhengping Hu, Ning Li, Xiaobo Cen, Hongbo Wang, Jingwei Tian
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Opiates produce analgesia via G-protein signaling, and adverse effects, such as respiratory depression and decreased bowel motility, by β-arrestin pathway. Oliceridine, a G protein-biased MOR agonist, only presents modest safety advantages as compar
Externí odkaz:
https://doaj.org/article/171eca7687f743f59105a10c35232dfc
Autor:
Haibo Zhu, Wenyan Wang, Chunjie Sha, Wei Guo, Chunmei Li, Fengjuan Zhao, Hongbo Wang, Wanglin Jiang, Jingwei Tian
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Toludesvenlafaxine hydrochloride dihydrate is a novel chemical entity and a potential triple monoamine reuptake inhibitor. This study characterized the in vitro triple reuptake inhibition activity, antidepressant-like activity in animals, and pharmac
Externí odkaz:
https://doaj.org/article/c2ef94b8fc7948e1895c9b840b67c0ed
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Tirbanibulin (KX-01) is the first clinical Src inhibitor of the novel peptidomimetic class that targets the peptide substrate site of Src providing more specificity toward the Src kinase. This study assessed the impact of KX-01 on cobalt chloride (Co
Externí odkaz:
https://doaj.org/article/d85ce68a191b4bf0b46e99b542c09256
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Pulmonary rehabilitation mixture (PRM), a Chinese herbal medicine formula, has been used to treat pulmonary fibrosis for decades. In this study, we systematically evaluated the pharmacodynamic and pharmacokinetic performance of PRM. The phar
Externí odkaz:
https://doaj.org/article/121ab20e0e60459e8a32835b7b03323a
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Raltegravir, an inhibitor of human immunodeficiency virus-1 (HIV-1) integrase, has been used to treat HIV/acquired immunodeficiency syndrome; however, its therapeutic effects on pulmonary fibrosis have not been investigated. In this study, the in vit
Externí odkaz:
https://doaj.org/article/2cbec001c8a041898b61fb2da0cd912c
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 51, Iss 10 (2018)
Glucocorticoid insensitivity is an important barrier to the treatment of several inflammatory diseases, including acute lung injury (ALI). Saquinavir (SQV) is an inhibitor of the human immunodeficiency virus protease, and the therapeutic effects of S
Externí odkaz:
https://doaj.org/article/8c767fa05ba840e2a45df1acc17f746b
Autor:
Bin Liu, Hongyu Chen, Chunmei Li, Yana Guan, Wanglin Jiang, Hanrong Wang, Wei Guo, Wen Wen, Xiaobo Cen, Hongbo Wang, Jingwei Tian
Publikováno v:
Reproductive Toxicology. 119:108403
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c90d4099a39dfda23e6e1becc67117f6
https://doi.org/10.1016/j.reprotox.2023.108403
https://doi.org/10.1016/j.reprotox.2023.108403
Publikováno v:
Brazilian Journal of Medical and Biological Research v.55 2022
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Disruption of pulmonary endothelial permeability and associated barrier integrity increase the severity of acute respiratory distress syndrome (ARDS). This study investigated the potential ability of the human immunodeficiency virus-1 (HIV-1) integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb555dd6d4d673e896d7911ac6601c1
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100667
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100667
Autor:
Hongbo Wang, Aixia Zuo, Chunmei Li, Yang Zhang, Yonghai Wang, Wanglin Jiang, Jingwei Tian, Wentao Wu, Xiaochen Zhang, Wenyan Wang, Yifei Yang, Xiaobo Cen, Xin Che
Publikováno v:
European journal of medicinal chemistry. 228
Biased agonism refers to the ability of compounds to drive preferred signaling pathways and avoid adverse signaling pathways in a ligand-dependent manner for some G-protein–coupled receptors. It is thought that the separation of therapeutic efficac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e3acdfc6df4644e60b7af98f855e04
https://pubmed.ncbi.nlm.nih.gov/34802839
https://pubmed.ncbi.nlm.nih.gov/34802839
Autor:
Liang Ye, Zhengping Hu, Hui Wang, Haibo Zhu, Zhaoju Dong, Wanglin Jiang, Huijuan Zhao, Ning Li, Wei Mi, Wenyan Wang, Xihou Hu
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140281 (2015)
Tris-(2,3-dibromopropyl) isocyanurate (TDBP-TAZTO), an emerging brominated flame retardant, possesses the characteristics of candidate persistent organic pollutants and has displayed toxicity to fish and rodents. TDBP-TAZTO can pass through the blood
Externí odkaz:
https://doaj.org/article/61c23c958d9a4148b457fa9663986140